鄰近類別 會議論文/會議摘要 [23/37] 專利 [0/18] 類別統計 近3年內發表的文件:19(12.10%) 含全文筆數:157(100.00%) 文件下載次數統計 下載大於0次:157(100.00%) 下載大於100次:153(97.45%) 檔案下載總次數:84733(86.94%) 最後更新時間: 2024-11-29 01:31 上傳排行 資料載入中..... 下載排行 資料載入中..... 最近上傳 DBPR116, a prodrug of BPRMU191, in ... Discovery of a mu-opioid receptor m... Discovery of a long half-life AURKA... Postfermented tea extract potently ... Natural fucoidans inhibit coronavir... Development of furanopyrimidine-bas... The synergistic inhibition of coron... Omicron-specific mRNA vaccine induc... BPR0C261, an analogous of microtubu... Protective effect of CXCR4 antagoni...

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日期	題名	關聯
2024-10-29	DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration	Journal of Medicinal Chemistry. 2024 Oct 29;Article in Press.
2024-07-17	Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia	Cell Chemical Biology. 2024 Jul 17;Article in Press.
2024-06-01	Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus	Molecular Cancer Therapeutics. 2024 Jun 01;23(6):766-779.
2024-02-16	Postfermented tea extract potently alleviates glucose metabolism disorders in vitro and in vivo	ACS Food Science and Technology. 2024 Feb 16;4(2):479-490.
2023-07-20	Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin	Biochemical Pharmacology. 2023 Jul 20;215:Article number 115688.
2023-02-07	Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer	Journal of Medicinal Chemistry. 2023 Feb 7;66(4):2566-2588.
2023-01-19	The synergistic inhibition of coronavirus replication and induced cytokine production by ciclesonide and the tylophorine-based compound dbq33b [Erratum:Pharmaceutics. 2022 Jul 21;14(7):Article number 1511.]	Pharmaceutics. 2023 Jan 19;15(2):Article number 342.
2022-12-05	Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation	European Journal of Medicinal Chemistry. 2022 Dec 5;243:Article number 114728.
2022-12-02	Omicron-specific mRNA vaccine induced cross-protective immunity against ancestral SARS-CoV-2 infection with low neutralizing antibodies	Journal of Medical Virology. 2022 Dec 2;95:Article number e28370.
2022-11-15	BPR0C261, an analogous of microtubule disrupting agent D-24851 enhances the radiosensitivity of human non-small cell lung cancer cells via p53-dependent and p53-independent pathways	International Journal of Molecular Sciences. 2022 Nov 15;23(22):Article number 14083.
2022-11-01	Peritoneal effluent MicroRNA profile for detection of encapsulating peritoneal sclerosis	Clinica Chimica Acta. 2022 Nov 1;536:45-55.
2022-11	Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone	Bioorganic Chemistry. 2022 Nov;128:Article number 105905.
2022-10-13	Targeting the phosphatidylserine-immune checkpoint with a small-molecule maytansinoid conjugate	Journal of Medicinal Chemistry. 2022 Oct 13;65(19):12802-12824.
2022-10-03	Protective effect of CXCR4 antagonist DBPR807 against ischemia-reperfusion injury in a rat and porcine model of myocardial infarction: Potential adjunctive therapy for percutaneous coronary intervention	International Journal of Molecular Sciences. 2022 Oct 3;23(19):Article number 11730.
2022-07-21	The synergistic inhibition of coronavirus replication and induced cytokine production by ciclesonide and the tylophorine-based compound dbq33b	Pharmaceutics. 2022 Jul 21;14(7):Article number 1511.
2022-06-21	Synthesis and evaluation of small molecule drug conjugates harnessing thioester-linked maytansinoids	Pharmaceutics. 2022 Jun 21;14(7):Article number 1316.
2022-05-02	Furin and TMPRSS2 resistant spike induces robust humoral and cellular immunity against SARS-CoV-2 lethal infection	Frontiers in Immunology. 2022 May 2;13:Article number 872047.
2022-03-02	Discovery of potential neuroprotective agents against paclitaxel-induced peripheral neuropathy	Journal of Medicinal Chemistry. 2022 Mar 2;65(6):4767-4782.
2022-02-15	Click chemistry and multicomponent reaction for linker diversification of zinc dipicolylamine-based drug conjugates	Frontiers in Chemistry. 2022 Feb 15;9:Article number 822587.
2021-12	Implanted islet mass influences the effects of dipeptidyl peptidase-IV inhibitor LAF237 on transplantation outcomes in diabetic mice	Biomedical Journal. 2021 Dec;44(6 Suppl 2):S210-S217.
2021-11-15	Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization	European Journal of Medicinal Chemistry. 2021 Nov 15;224:Article number 113673.
2021-10-14	Discovery of BPR1R024, an orally active and selective CSF1R inhibitor that exhibits antitumor and immunomodulatory activity in a murine colon tumor model	Journal of Medicinal Chemistry. 2021 Oct 14;64(19):14477-14497.
2021-10-01	Engineering nano- and microparticles as oral delivery vehicles to promote intestinal lymphatic drug transport	Advanced Materials. 2021 Oct 01;201:Article number 2104139.
2021-08-13	Remdesivir and cyclosporine synergistically inhibit the human coronaviruses OC43 and SARS-CoV-2	Frontiers in Pharmacology. 2021 Aug 13;12:Article number 706901.
2021-08-01	DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity	Life Sciences. 2021 Aug 1;278:Article number 119574.

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