2014-01-08 |
Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer |
PLoS ONE. 2014 Jan 8;9(1):Article number e83160. |
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2013-11 |
BPR0C305, an orally active microtubule-disrupting anticancer agent |
Anticancer Drugs. 2013 Nov;24(10):1047-1057. |
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2013-10 |
Noninvasive imaging oral absorption of insulin delivered by nanoparticles and its stimulated glucose utilization in controlling postprandial hyperglycemia during OGTT in diabetic rats |
Journal of Controlled Release. 2013 Oct;172(2):513-522. |
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2013-10 |
Combination therapy via oral co-administration of insulin- and exendin-4-loaded nanoparticles to treat type 2 diabetic rats undergoing OGTT |
Biomaterials. 2013 Oct;34(32):7994-8001. |
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2013-07 |
Andrographis paniculata extract and andrographolide modulate the hepatic drug metabolism system and plasma tolbutamide concentrations in rats |
Evidence-Based Complementary and Alternative Medicine. 2013 Jul;2013:Article number 982689. |
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2013-06-28 |
Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor |
Journal of Medicinal Chemistry. 2013 Jun 28;56(13):5247-5260. |
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2013-06 |
Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) |
Bioorganic and Medicinal Chemistry. 2013 Jun;21(11):2856-2867. |
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2013-06 |
Candida albicans ENO1 null mutants exhibit altered drug susceptibility, hyphal formation, and virulence |
Journal of Microbiology. 2013 Jun;51(3):345-351. |
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2013-05 |
H2O2 accumulation mediates differentiation capacity alteration, but not proliferative decline in senescent human fetal mesenchymal stem cells |
Antioxidants and Redox Signaling. 2013 May;18(15):1895-1905. |
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2013-05 |
Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules |
Proceedings of the National Academy of Sciences of the United States of America. 2013 May;110(19):E1779-E1787. |
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2013-01-23 |
In vivo imaging of brain infarct with the novel fluorescent probe psvue 794 in a rat middle cerebral artery occlusion-reperfusion model |
Molecular Imaging. 2013 Jan 23;12(1):8-16. |
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2013-01 |
Effects of pH on molecular mechanisms of chitosan–integrin interactions and resulting tight-junction disruptions |
Biomaterials. 2013 Jan;34(3):784-793. |
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2012-09 |
Elucidating the signaling mechanism of an epithelial tight-junction opening induced by chitosan |
Biomaterials. 2012 Sep;33(26):6254-6263. |
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2012-09 |
Synthesis and biological evaluation of novel C-indolylxylosides as sodium-dependent glucose co-transporter 2 inhibitors |
European Journal of Medicinal Chemistry. 2012 Sep;55:32-38. |
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2012-09 |
Putative tumor metastasis-associated genes in human gastric cancer |
International Journal of Oncology. 2012 Sep;41(3):1068-1084. |
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2012-09 |
HDAC inhibitors augmented cell migration and metastasis through induction of PKCs leading to identification of low toxicity modalities for combination cancer therapy |
Clinical Cancer Research. 2012 Sep;18(17):4691-4701. |
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2012-06-07 |
3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) |
Bioorganic and Medicinal Chemistry Letters. 2012 Jun 7;22(14):4654-4659. |
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2012-04 |
Securin enhances the anti-cancer effects of 6-Methoxy-3-(3′,4′,5′-Trimethoxy-Benzoyl)-1H-Indole (BPR0L075) in human colorectal cancer cells |
PLoS ONE. 2012 Apr;7(4):Article number e36006. |
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2012-03 |
R432 is a key residue for the multiple functions of Ndt80p in Candida albicans |
Cellular and Molecular Life Sciences. 2012 Mar;69(6):1011-1023. |
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2012-02 |
Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents |
Investigational New Drugs. 2012 Feb;30(1):164-175. |
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2012-02 |
Discovery of novel stem cell mobilizers that target the CXCR4 receptor |
ChemMedChem. 2012 Feb;7(2):209-212. |
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2012-01 |
BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML |
British Journal of Cancer. 2012 Jan;106(3):475-481. |
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2011-11 |
Effects of chitosan-nanoparticle-mediated tight junction opening on the oral absorption of endotoxins |
Biomaterials. 2011 Nov;32(33):8712-8721. |
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2011-10 |
Antiproliferative effects of N-heterocyclic indolyl glyoxylamide derivatives on human lung cancer cells |
Anticancer Research. 2011 Oct;31(10):3407-3415. |
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2011-07 |
Immune response and pathophysiological features of Klebsiella pneumoniae liver abscesses in an animal model |
Laboratory Investigation. 2011 Jul;91(7):1029-1039. |
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