國家衛生研究院 NHRI:
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    近3年内发表的文件:13(5.63%)
    含全文笔数:171(74.03%)

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    显示项目76-100 / 231. (共10页)
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    日期题名關聯
    2014-03-20 Fused bicyclic pyrimidine compounds as aurora kinase inhibitors JP5502072/2014-03-20
    2014-03 DBPR112, a potent and selective EGFR kinase inhibitor in preclinical study Abstracts of Papers - American Chemical Society. 2014 Mar;247:Article number 315-MEDI.
    2014-03 Efficient virtual screening using ligand efficiency based approach Abstracts of Papers - American Chemical Society. 2014 Mar;247:Article number 55-MEDI.
    2013-11-21 治療癌症的醫藥組成物 I415852/2013-11-21
    2013-11 A development drug candidate targeting EGFR kinase for lung cancer: DBPR112 Journal of Thoracic Oncology. 2013 Nov;8(Suppl. 2):S779-S780.
    2013-11 Peptide-mediated liposomal doxorubicin enhances drug delivery efficiency and therapeutic efficacy in lung cancer animal models Journal of Thoracic Oncology. 2013 Nov;8(Suppl. 2):S779.
    2013-10-01 喹啉化合物及包含其之治療病毒感染之醫藥組成物 I410245/2013-10-01
    2013-09-22 A novel Aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatment [Erratum:International Journal of Biological Sciences. 2013 Apr 29;9(4):403-411] International Journal of Biological Sciences. 2013 Sep 22;9(9):947.
    2013-08-21 Fused multicyclic compounds as protein kinase inhibitors EP2331530B1/2013-08-21
    2013-08-13 Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors US8507502B2/2013-08-13
    2013-07-25 Pronounced induction of endoplasmic reticulum stress and tumor suppression by surfactant-free poly(lactic-co-glycolic acid) nanoparticles via modulation of the PI3K signaling pathway International Journal of Nanomedicine. 2013 Jul 25;2013(8):2689-2707.
    2013-07-01 做為蛋白質激酶抑制劑之稠合多環化合物 I400242/2013-07-01
    2013-06-28 Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor Journal of Medicinal Chemistry. 2013 Jun 28;56(13):5247-5260.
    2013-06 An antimitotic and antivascular agent BPR0L075 overcomes multidrug resistance and induces mitotic catastrophe in paclitaxel-resistant ovarian cancer cells PLoS ONE. 2013 Jun;8(6):Article number e65686.
    2013-05 Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules Proceedings of the National Academy of Sciences of the United States of America. 2013 May;110(19):E1779-E1787.
    2013-05 Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors Journal of Medicinal Chemistry. 2013 May;56(10):3889-3903.
    2013-04-29 A novel Aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatment International Journal of Biological Sciences. 2013 Apr 29;9(4):403-411.
    2013-04-07 BPR000K, a novel Aurora kinase inhibitor Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 300-MEDI.
    2013-04-07 Kinase-focused library: Design and synthesis of pyrimidines derivatives bearing amino substituents using high throughput parallel synthesis Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 298-MEDI
    2013-04-07 3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 87-MEDI.
    2013-04-07 Development drug candidate targeting EGFR kinase: DBPR112 Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 299-MEDI.
    2013-04 Design and synthesis of Aurora kinase inhibitors as anticancer agents Abstracts of Papers - American Chemical Society. 2013 Apr;245:Article number 301-MEDI.
    2013-02-20 Parallel screening of Wild-Type and drug-resistant targets for anti-resistance neuraminidase inhibitors PLoS ONE. 2013 Feb 20;8(2):Article number e56704.
    2013-02-11 作為酪胺酸激酶抑制劑之稠合雙環及多環嘧啶化合物 I385174/2013-02-11
    2013-01 3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor ChemMedChem. 2013 Jan;8(1):136-148.

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