| 2008-05 |
Bioassay-guided purification and identification of PPARa/gamma agonists from Chlorella sorokiniana |
Phytotherapy Research. 2008 May;22(5):605-613. |
 |
| 2008-04-15 |
Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus |
Biochemical Pharmacology. 2008 Apr;75(8):1601-1609. |
|
| 2008-03-13 |
Synthesis and biological evaluation of 1-methyl-2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors |
Journal of Medicinal Chemistry. 2008 Mar;51(5):1464-1468. |
|
| 2008-03-10 |
Reactions of 2-hydroxybenzophenones with Corey-Chaykovsky reagent |
Tetrahedron. 2008 Mar;64(11):2586-2595. |
|
| 2008-03-01 |
Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold |
Bioorganic and Medicinal Chemistry Letters. 2008 Mar;18(5):1623-1627. |
|
| 2008-02-11 |
一種抗病毒之醫藥組合物 |
I293248/2008-02-11 |
|
| 2008-02-07 |
First total syntheses of (+/-)-annuionone B and (+/-)-tanarifuranonol |
Organic Letters. 2008 Feb 7;10(3):449-452. |
|
| 2008-02 |
A novel peroxisome proliferator-activated receptor alpha/gamma agonist, BPR1H0101, inhibits topoisomerase II catalytic activity in human cancer cells |
Anti-Cancer Drugs. 2008 Feb;19(2):151-158. |
|
| 2007-12 |
Strategies of development of antiviral agents directed against influenza virus replication |
Current Pharmaceutical Design. 2007 Dec;13(34):3531-3542. |
|
| 2007-09-06 |
4-and 5-aroylindoles as novel classes of potent antitubulin agents |
Journal of Medicinal Chemistry. 2007 Sep;50(18):4548-4552. |
|
| 2007-07-31 |
Combined modalities of resistance in an oxaliplatin-resistant human gastric cancer cell line with enhanced sensitivity to 5-fluorouracil |
British Journal of Cancer. 2007 Jul;97(3):334-344. |
|
| 2007-07 |
Biotransformation of 6-methoxy-3-(3 ',4 ',5 '-trimethoxy-benzoyl)-1-hindole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes |
Drug Metabolism and Disposition. 2007 Jul;35(7):1042-1049. |
|
| 2007-07 |
Anti-influenza drug discovery |
Drugs of the Future. 2007 Jul;32(Suppl. A):97. |
|
| 2007-07 |
From bench to drug candidate: Design and synthesis of 5,6-fused heteroaromatics as anticancer agents |
Drugs of the Future. 2007 Jul;32(Suppl. A):34-35. |
|
| 2007-03-01 |
3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes |
Bioorganic and Medicinal Chemistry Letters. 2007 Mar;17(5):1274-1279. |
|
| 2007-02-08 |
Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells |
Cancer Letters. 2007 Feb;246(1-2):237-252. |
|
| 2007-02-01 |
Development and validation of a liquid chromatography-tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: Application to a pharmacokinetic study |
Journal of Chromatography B. 2007 Feb;846(1-2):162-168. |
|
| 2006-12 |
Pharmacokinetics of anti-SARS-CoV agent niclosamide and its analogs in rats |
Journal of Food and Drug Analysis. 2006 Dec;14(4):329-333. |
|
| 2006-11-16 |
7-aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents |
Journal of Medicinal Chemistry. 2006 Nov;49(23):6656-6659. |
|
| 2006-11 |
Combined modalities of resistance in an oxaliplaitin-resistant human gastric cancer cell line with enhanced sensitivity |
EJC Supplements. 2006 Nov;4(12):59. |
|
| 2006-10-19 |
Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists |
Journal of Medicinal Chemistry. 2006 Oct;49(21):6421-6424. |
|
| 2006-10 |
Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents |
ChemMedChem. 2006 Oct;1(10):1106-1118. |
|
| 2006-09 |
MEDI 416-3- 2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino -3-methyl-butyr amide analogs as DPP-IV inhibitors for the treatment of type-II diabetes |
Abstracts of Papers - American Chemical Society. 2006 Sep;232:MEDI 416. |
|
| 2006-08-24 |
Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease |
Journal of Medicinal Chemistry. 2006 Aug;49(17):5154-5161. |
|
| 2006-07 |
Antiviral drug discovery against SARS-CoV |
Current Medicinal Chemistry. 2006 Jul;13(17):2003-2020. |
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ORCID:0000-0002-1332-005X6
