子类别 專利 [0/42] 期刊論文 [141/141] 會議論文/會議摘要 [30/48] 邻近社群 伍素瑩 [52/65] 其他 [58/60] 夏克山 [76/98] 岳嶽 [29/32] 張仲明 [7/9] 張俊彥 [18/18] 張竣評 [21/26] 徐祖安 [170/215] 李秀珠 [75/105] 李靜琪 [23/24] 林書玉 [19/20] 洪明秀 [31/40] 潘秀玲(2009-2013) [16/17] 王文傑 [13/15] 王鴻俊 [7/7] 石全(2014-2017) [35/39] 童俊維 [23/23] 紀雅惠 [21/25] 翁紹華 [22/24] 莊宏 [1/1] 葉修華 [24/25] 葉燈光 [133/152] 蔣維棠 [41/66] 趙宇生(2002-2013) [120/212] 郭靜娟 [49/55] 鄒倫 [28/29] 陳志豪 [31/52] 陳新(2002-2015) [53/67] 陳炯東 [180/212] 顏婉菁 [6/7] 許明珠(1997-2001) [3/10] 陳淑貞(1998-2001) [3/11] 陳華鍵(1997-2001) [9/9] 社群统计 近3年内发表的文件:13(5.63%) 含全文笔数:171(74.03%) 文件下载次数统计 下载大于0次:171(100.00%) 下载大于100次:168(98.25%) 全文下载总次数:101952(1.90%) 最后更新时间: 2024-12-01 10:22 上传排行 数据加载中..... 下载排行 数据加载中..... 最近上传 DBPR116, a prodrug of BPRMU191, in ... Discovery of dual MER/AXL kinase in... Macrophage-mediated controlled rele... Targeting cathepsin S promotes acti... Discovery of novel AXL and MER inhi... Influence of ring strain on the for... A dual nociceptin and mu opioid rec... Development of furanopyrimidine-bas... A critical overview of current prog... Recent advances in total synthesis ...

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日期	题名	關聯
2024-10-29	DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration	Journal of Medicinal Chemistry. 2024 Oct 29;Article in Press.
2024-06-24	Macrophage-mediated controlled release of cysteine protease inhibitor from PLGA-PEG/hydroxyapatite microspheres for targeting cathepsin S in Alzheimer's disease	European Polymer Journal. 2024 Jun 24;214:Article number 113151.
2024-06-24	Discovery of dual MER/AXL kinase inhibitors as bifunctional small molecules for inhibiting tumor growth and enhancing tumor immune microenvironment	Journal of Medicinal Chemistry. 2024 Jun 24;Article in Press.
2024-05-09	Targeting cathepsin S promotes activation of OLF1-BDNF/TrkB axis to enhance cognitive function	Journal of Biomedical Science. 2024 May 09;31:Article number 46.
2023-11-03	Influence of ring strain on the formation of rearrangement vs cyclization isotwistane products in the acyl radical reaction of bicyclo[2.2.2]octanone	Organic Letters. 2023 Nov 3;25(43):7757-7762.
2023-10-05	A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects	European Journal of Medicinal Chemistry. 2023 Oct 05;258:Article number 115608.
2023-10	Discovery of novel AXL and MER inhibitors as potential anticancer and immune modulator drugs	Annals of Oncology. 2023 Oct;34(Suppl. 2):S214.
2023-02-07	Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer	Journal of Medicinal Chemistry. 2023 Feb 7;66(4):2566-2588.
2022-09-12	A critical overview of current progress for COVID-19: Development of vaccines, antiviral drugs, and therapeutic antibodies	Journal of Biomedical Science. 2022 Sep 12;29:Article number 68.
2022-08-09	Recent advances in total synthesis of natural products by masked ortho-benzoquinones	Journal of the Chinese Chemical Society. 2022 Aug 09;69(8):1210-1222.
2022-05-09	Natural product myricetin is a pan-KDM4 inhibitor which with poly lactic-co-glycolic acid formulation effectively targets castration-resistant prostate cancer	Journal of Biomedical Science. 2022 May 9;29:Article number 29.
2022-04-06	Identification of entry inhibitors against delta and omicron variants of SARS-CoV-2	International Journal of Molecular Sciences. 2022 Apr 6;23(7):Article number 4050.
2022-01-21	Novel FLT3/AURK multikinase inhibitor is efficacious against sorafenib-refractory and sorafenib-resistant hepatocellular carcinoma	Journal of Biomedical Science. 2022 Jan 21;29:Article number 5.
2021-11-15	Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization	European Journal of Medicinal Chemistry. 2021 Nov 15;224:Article number 113673.
2021-10-14	Discovery of BPR1R024, an orally active and selective CSF1R inhibitor that exhibits antitumor and immunomodulatory activity in a murine colon tumor model	Journal of Medicinal Chemistry. 2021 Oct 14;64(19):14477-14497.
2021-07-16	Colloidal assemblies composed of polymeric micellar/emulsified systems integrate cancer therapy combining a tumor-associated antigen vaccine and chemotherapeutic regimens	Nanomaterials. 2021 Jul 16;11(7):Article number 1844.
2021-04-16	Development of a robust scale-up synthetic route for BPR1K871: A clinical candidate for the treatment of acute myeloid leukemia and solid tumors	Organic Process Research and Development. 2021 Apr 16;25(4):817-830.
2021-04-13	Chlorinated briarane diterpenoids from octocoral Briareum stechei (Kükenthal, 1908)	Tetrahedron Letters. 2021 Apr 13;69:Article number 152976.
2021-02-22	Mimicking H3 substrate arginine in the design of G9a lysine methyltransferase inhibitors for cancer therapy: A computational study for structure-based drug design	ACS Omega. 2021 Feb 22;6(9):6100-6111.
2021-01-31	Briarenols W-Z: Chlorine-containing polyoxygenated briaranes from octocoral briareum stechei (Kükenthal, 1908)	Marine Drugs. 2021 Jan 31;19(2):Article number 77.
2021-01-15	One-pot synthesis of dibenzo[b,f]oxepines and total synthesis of bauhinoxepin C	Journal of Organic Chemistry. 2021 Jan 15;86(2):1955-1963.
2021-01	Overcoming vincristine resistance in cancer: Computational design and discovery of piperine-inspired P-glycoprotein inhibitors	Chemical Biology and Drug Design. 2021 Jan;97(1):51-66.
2020-12-10	Tumor-agnostic inhibitors in oncology: A new phase for precision medicine	Journal of the Chinese Chemical Society. 2020 Dec 10;67(12):2216-2224.
2020-08	Design of a potent anticancer lead inspired by natural products from traditional Indian medicine	Journal of Biomolecular Structure and Dynamics. 2020 Aug;38(12):3563-3577.
2020-07	Design of drug-like hepsin inhibitors against prostate cancer and kidney stones	Acta Pharmaceutica Sinica B. 2020 Jul;10(7):1309-1320.

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