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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/9111


    Title: 作為酪胺酸激酶抑制劑之稠合雙環及多環嘧啶化合物
    Other Titles: Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors
    Authors: Hsieh, HP;Coumar, MS;Chao, YS;Hsu, TA;Lin, WH;Chen, YR
    Contributors: Institute of Biotechnology and Pharmaceutical Research;Institute of Molecular and Genomic Medicine
    Abstract: 本發明係有關於一種式(I)之稠合雙環或多環化合物:其中,A、B、C、X、Y、m及n係定義於本文中。本發明亦揭露一種抑制EGFR激酶活性的方法,以及一種以這些化合物治療癌症之方法。Fused bicyclic or tricyclic compounds of formula (I): wherein A, B, C, X, Y, m, and n are defined herein. Also disclosed are a method for inhibiting EGFR kinase activity and a method for treating cancer with these compounds.
    Date: 2013-02-11
    Relation: I385174/2013-02-11
    Link to: https://twpat1.tipo.gov.tw/tipotwoc/tipotwkm?!!FR_I385174
    Appears in Collections:[謝興邦] 專利
    [趙宇生(2002-2013)] 專利
    [徐祖安] 專利
    [陳怡榮] 專利

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