| 2023-03-17 |
A convenient diels-alder approach toward potential polyketide-like antibiotics using alpha-activated alpha,Beta-unsaturated 4,4-dimethyl-1-tetralones as dienophiles |
Molecules. 2023 Mar 17;28(6):Article number 2739. |
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| 2023-01 |
Modulating the affinity and signaling bias of cannabinoid receptor 1 antagonists |
Bioorganic Chemistry. 2023 Jan;130:Article number 106236. |
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| 2022-10-03 |
Protective effect of CXCR4 antagonist DBPR807 against ischemia-reperfusion injury in a rat and porcine model of myocardial infarction: Potential adjunctive therapy for percutaneous coronary intervention |
International Journal of Molecular Sciences. 2022 Oct 3;23(19):Article number 11730. |
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| 2022-03-02 |
Discovery of potential neuroprotective agents against paclitaxel-induced peripheral neuropathy |
Journal of Medicinal Chemistry. 2022 Mar 2;65(6):4767-4782. |
|
| 2021-07-21 |
Anionic diels-alder chemistry of cyclic sodium dien-1-olates delivering highly stereoselective and functionalized polycyclic adducts |
Organic Letters. 2021 Jul 21;23(15):5709-5713. |
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| 2021-03-30 |
A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment |
Proceedings of the National Academy of Sciences of the United States of America. 2021 Mar 30;118(13):Article number e2015433118. |
|
| 2021-03-02 |
Total synthesis of landomycins Q and R and related core structures for exploration of the cytotoxicity and antibacterial properties |
RSC Advances. 2021 Mar 2;11(16):9426-9432. |
|
| 2020-09-25 |
Protective effect of CXCR4 antagonist CX807 in a rat model of hemorrhagic stroke |
International Journal of Molecular Sciences. 2020 Sep 25;21(19):Article number 7085. |
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| 2020-04 |
Development of a cross-conjugated vinylogous [4+2] anionic annulation and application to the total synthesis of natural antibiotic (±)-ABX |
Angewandte Chemie. 2020 Apr;59(16):6540-6545. |
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| 2020-02-10 |
Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors |
Journal of Medicinal Chemistry. 2020 Feb 10;63(4):1642-1659. |
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| 2020-01-16 |
Development of a cross-conjugated vinylogous [4+2] anionic annulation and application to the total synthesis of natural antibiotic (±)-ABX |
Advanced Materials. 2020 Jan 16;132(16):6602-6607. |
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| 2020-01-06 |
Biosynthetic engineering of the antifungal, anti-MRSA auroramycin |
Microbial Cell Factories. 2020 Jan 6;19:Article number 3. |
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| 2019-07-11 |
Linker optimization and therapeutic evaluation of phosphatidylserine-targeting zinc dipicolylamine-based drug conjugates |
Journal of Medicinal Chemistry. 2019 Jul 11;62(13):6047-6062. |
|
| 2019-05 |
Characterization, dynamics, and mechanism of CXCR4 antagonists on a constitutively active mutant |
Cell Chemical Biology. 2019 May;26(5):662-673.e7. |
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| 2019-01-01 |
Fluorine-18 isotope labeling for positron emission tomography imaging. Direct evidence for DBPR211 as a peripherally restricted CB1 inverse agonist |
Bioorganic and Medicinal Chemistry. 2019 Jan 1;27(1):216-223. |
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| 2018-12-07 |
Temperature-controlled thiation of alpha-Cyano-beta-Alkynyl carbonyl derivatives for de vovo synthesis of 2-Aminothiophenes and thieno[2,3- c]isothiazoles |
Journal of Organic Chemistry. 2018 Dec 7;83(23):14688-14697. |
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| 2018-08 |
Auroramycin: A potent antibiotic from streptomyces roseosporus by CRISPR-Cas9 activation |
Chembiochem: A European Journal of Chemical Biology. 2018 Aug;19(16):1716-1719. |
|
| 2018-07 |
Harnessing CXCR4 antagonists in stem cell mobilization, HIV infection, ischemic diseases, and oncology |
Medicinal Research Reviews. 2018 Jul;38(4):1188-1234. |
|
| 2018-07 |
Synergic effect of curcumin and its structural analogue (Monoacetylcurcumin) on anti-influenza virus infection |
Journal of Food and Drug Analysis. 2018 Jul;26(3):1015-1023. |
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| 2018-05-22 |
Total synthesis of tetarimycin A, (±)-Naphthacemycin A9, and (±)-Fasamycin A: structure-activity relationship studies against drug-resistant bacteria |
Journal of Organic Chemistry. 2018 May 22;83(12):6508-6523. |
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| 2018-02-08 |
Development of stem-cell-mobilizing agents targeting CXCR4 receptor for peripheral blood stem cell transplantation and beyond |
Journal of Medicinal Chemistry. 2018 Feb 8;61(3):818-833. |
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| 2017-07 |
Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates |
Bioconjugate Chemistry. 2017 Jul;28(7):1878-1892. |
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| 2017-04 |
A novel CXCR4 antagonist CX549 induces neuroprotection in stroke brain |
Cell Transplantation. 2017 Apr;26(4):571-583. |
|
| 2016-12-08 |
Bromomethylthioindole inspired carbazole hybrids as promising class of anti-MRSA agents |
ACS Medicinal Chemistry Letters. 2016 Dec 8;7(12):1191-1196. |
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| 2016-11-18 |
Cobalt(II)-catalyzed aerobic oxidation of terminal-capped alkynyl alpha-cyano alkanone systems. An oxygen-mediated radical chain reaction |
Journal of Organic Chemistry. 2016 Nov 18;81(22):10759-10768. |
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| 2016-01 |
Synthesis of (E)-oxindolylidene acetate using tandem palladium-catalyzed Heck and alkoxycarbonylation reactions |
Organic and Biomolecular Chemistry. 2016 Jan;14(1):220-228. |
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| 2016-01 |
Important hydrogen bond networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) inhibitor design revealed by crystal structures of imidazoleisoindole derivatives with IDO1 |
Journal of Medicinal Chemistry. 2016 Jan;59 (1):282-293. |
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| 2015-08-14 |
Studies on antibiotics active against resistant bacteria. Total synthesis of MRSA-active tetarimycin A and its analogues |
Organic Letters. 2015 Aug 14;17(17):4248-4251. |
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| 2015-06-15 |
Synthesis and evaluation of 3-ylideneoxindole acetamides as potent anticancer agents |
European Journal of Medicinal Chemistry. 2015 Jun 15;98:1-12. |
|
| 2015-06-15 |
The total synthesis of retrojusticidin B, justicidin E, and helioxanthin |
Journal of Organic Chemistry. 2015 Jun 15;80(13):6708-6714. |
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| 2015-05 |
A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis |
Diabetes, Obesity and Metabolism. 2015 May;17(5):495-504. |
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| 2015-03 |
Stem cell mobilizers targeting chemokine receptor CXCR4: Renoprotective application in acute kidney injury |
Journal of Medicinal Chemistry. 2015 Mar;58(5):2315-2325. |
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| 2015-02 |
Function-oriented development of CXCR4 antagonists as selective human immunodeficiency virus (HIV)-1 entry inhibitors |
Journal of Medicinal Chemistry. 2015 Feb;58(3):1452-1465. |
|
| 2014-10 |
Manganese(III)-catalyzed oxidative cyclization of aryl 1-cyanoalk-5-ynyl ketone systems: A convenient and general approach to cyclopenta[b]naphthalene derivatives |
Advanced Synthesis and Catalysis. 2014 Oct;356(14-15):3025-3038. |
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| 2014-03 |
Double michael addition reactions of the nazarov reagent with 2-cyano-2-cycloalkenones: An alternative approach to cis-fused bicyclic systems |
Synlett. 2014 Mar;25(4):543-546. |
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| 2013-11-13 |
Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice |
Journal of Medicinal Chemistry. 2013 Nov 13;56(24):9920-9933. |
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| 2013-04 |
Palladium(0)/copper(I)-catalyzed tandem cyclization of aryl 1-cyanoalk-5-ynyl ketone system: Rapid assembly of cyclopenta[b]naphthalene and benzo[b]fluorene derivatives |
Advanced Synthesis and Catalysis. 2013 Apr;355(7):1323-1337. |
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| 2012-12 |
Tandem cyclization of alpha-Cyano alpha-Alkynyl aryl ketones induced by tert-Butyl hydroperoxide and tetrabutylammonium iodide |
Organic Letters. 2012 Dec;14(23):6024-6027. |
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| 2012-11-20 |
Beckmann rearrangement of ketoximes induced by phenyl dichlorophosphate at ambient temperature |
Molecules. 2012 Nov 20;17(11):13662-13672. |
|
| 2012-07 |
Induction of fatty acid oxidation resists weight gain, ameliorates hepatic steatosis and reduces cardiometabolic risk factors |
International Journal of Obesity. 2012 Jul;36(7):999-1006. |
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| 2012-07 |
K2CO3/NaI-induced cyclization of omega-bromo alpha-cyano ketones: A new annulation approach for the formation of carbalkoxycyclohexane ring system |
Synlett. 2012 Jul;23(11):1653-1656. |
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| 2012-05 |
Palladium(II) acetate mediated oxidative cyclization of omega-unsaturated alpha-cyano ketones for facile construction of methylenecyclohexane ring system |
Organic & Biomolecular Chemistry. 2012 May;10(23):4609-4617. |
|
| 2012-02 |
Discovery of novel stem cell mobilizers that target the CXCR4 receptor |
ChemMedChem. 2012 Feb;7(2):209-212. |
|
| 2011-07 |
Conia-ene annulation of the alpha-cyano Beta-TMS-capped alkynyl cycloalkanone system and its synthetic application |
Organic and Biomolecular Chemistry. 2011 Jul;9(13):4778-4781. |
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| 2011-06 |
Hot topic: Opportunities and potential challenges for the treatment of metabolic syndrome |
Current Topics In Medicinal Chemistry. 2011 Jun;11(12):1420. |
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| 2011-03-04 |
Autoxidative annulation cascade of the alpha-cyano beta-TMS-capped alkynyl cycloalkanone system |
Organic Letters. 2011 Mar 4;13(5):896-899. |
|
| 2010-10 |
Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities |
Pharmacological Research. 2010 Oct;62(4):337-343. |
|
| 2010-09 |
Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophe n-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist |
ChemMedChem. 2010 Sep;5(9):1439-1443. |
|
| 2010-08 |
Total synthesis of (-)-Isopisiferin: Confirmation of absolute configuration |
Journal of Organic Chemistry. 2010 Aug;2010(22):4271-4275. |
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| 2010-06 |
General approach to 2,3-dibenzyl-gamma-butyrolactone lignans: application to the total synthesis of (+/-)-5 '-methoxyyatein, (+/-)-5 '-methoxyclusin, and (+/-)-4 '-hydroxycubebinone |
European Journal of Organic Chemistry. 2010 Jun;2010(18):3473-3480. |
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