Making use of a tandem free radical cyclization process mediated by Mn(OAc)3 as a key operation, the total synthesis of retrojusticidin B, justicidin E, and helioxanthin has been concisely achieved in four or five steps in an overall yield of 45, 33 and 44%, respectively, from a common starting material 5.
Date:
2015-06-15
Relation:
Journal of Organic Chemistry. 2015 Jun 15;80(13):6708-6714.
