| [劉俊揚] 期刊論文 |
2024-11-15 |
The effects of acetylated cordycepin derivatives on promoting vascular angiogenesis and attenuating myocardial ischemic injury |
- |
 |
| [郭呈欽] 期刊論文 |
2024-09-18 |
Crosstalk between FTH1 and PYCR1 dysregulates proline metabolism and mediates cell growth in KRAS-mutant pancreatic cancer cells |
- |
|
| [郭呈欽] 期刊論文 |
2024-05-24 |
Identification of gut microbiome signatures associated with indole pathway in tryptophan metabolism in patients undergoing hemodialysis |
- |
|
| [黃東明] 期刊論文 |
2023-11 |
Lysosomal-targeted doxorubicin delivery using RBC-derived vesicles to overcome drug-resistant cancer through mitochondrial-dependent cell death |
- |
|
| [張俊彥] 期刊論文 |
2023-03-28 |
Synthesis and structure–activity relationship of salvinal derivatives as potent microtubule inhibitors |
- |
|
| [郭靜娟] 期刊論文 |
2023-02-28 |
How to deal with frenemy NRF2: Targeting NRF2 for chemoprevention and cancer therapy |
- |
|
| [王淑麗] 期刊論文 |
2023-02-24 |
Prenatal exposure to parabens in relation to childhood obesity and the gut microbiome |
- |
|
| [其他] 期刊論文 |
2023-01-10 |
Enriched peripheral blood-derived mononuclear cells for treating knee osteoarthritis |
- |
|
| [郭靜娟] 期刊論文 |
2023-01 |
Two new chromones and a new coumarin from the fruit of Cnidium monnieri (L.) Cusson |
- |
|
| [郭呈欽] 期刊論文 |
2022-11-17 |
Pharmacometabolomic study of drug response to antihypertensive medications for hypertension marker identification in Han Chinese individuals in Taiwan |
- |
|
| [伍焜玉] 期刊論文 |
2022-11-07 |
Cancer-derived extracellular succinate: A driver of cancer metastasis |
- |
|
| [翁紹華] 期刊論文 |
2022-02-05 |
Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design |
- |
|
| [郭靜娟] 期刊論文 |
2022-01-17 |
Pilot study: Nutritional and preclinical safety investigation of fermented hispidin-enriched sanghuangporus sanghuang mycelia: A promising functional food material to improve sleep |
- |
|
| [褚志斌] 期刊論文 |
2022-01-01 |
Comparison of laboratory diagnosis, clinical manifestation, and management of pulmonary cryptococcosis: Report of the clinical scenario and literature review |
- |
|
| [郭靜娟] 期刊論文 |
2021-12-14 |
A novel NRF2/ARE inhibitor gossypol induces cytotoxicity and sensitizes chemotherapy responses in chemo-refractory cancer cells |
- |
|
| [李俊賢] 期刊論文 |
2021-11-22 |
Incorporation of au nanoparticles on ZnO/ZnS core shell nanostructures for UV Light/Hydrogen gas dual sensing enhancement |
- |
|
| [郭呈欽] 期刊論文 |
2021-11-08 |
Restoration of 5-methoxytryptophan protects against atherosclerotic chondrogenesis and calcification in ApoE(-/-) mice fed high fat diet |
- |
|
| [其他] 期刊論文 |
2021-10-29 |
Type-3 hyaluronan synthase attenuates tumor cells invasion in human mammary parenchymal tissues |
- |
|
| [王淑麗] 期刊論文 |
2021-10-27 |
Association between prenatal exposure to metals and atopic dermatitis among children aged 4 years in Taiwan |
- |
|
| [伍焜玉] 期刊論文 |
2021-10-22 |
Association of tumor hydroxyindole o-methyltransferase and serum 5-methoxytryptophan with long-term survival of hepatocellular carcinoma |
- |
|
| [李啟明] 期刊論文 |
2021-09 |
5-Methoxytryptophan attenuates postinfarct cardiac injury by controlling oxidative stress and immune activation |
- |
|
| [郭靜娟] 期刊論文 |
2021-08-12 |
Xanthine derivatives reveal an allosteric binding site in methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) |
- |
|
| [龔行健] 期刊論文 |
2021-06-04 |
Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes |
- |
|
| [郭靜娟] 期刊論文 |
2021-03-15 |
Tea polyphenol epigallocatechin-3-gallate inhibits cell proliferation in a patient-derived triple-negative breast cancer xenograft mouse model via inhibition of proline-dehydrogenase-induced effects |
- |
|
| [郭靜娟] 期刊論文 |
2021-03-11 |
c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation |
- |
|
| [王淑麗] 期刊論文 |
2021-03 |
Association between arsenic exposure, DNA damage, and urological cancers incidence: A long-term follow-up study of residents in an arseniasis endemic area of northeastern Taiwan |
- |
|
| [王淑麗] 期刊論文 |
2021-01 |
Maternal and childhood exposure to inorganic arsenic and airway allergy – A 15-Year birth cohort follow-up study |
- |
|
| [郭呈欽] 期刊論文 |
2020-10 |
The role of 5-methoxytryptophan in pediatric-onset lupus nephritis: A retrospective cohort study |
- |
|
| [郭靜娟] 期刊論文 |
2020-08 |
Two new diprenylated flavanones from Derris laxiflora Benth |
- |
|
| [劉俊揚] 期刊論文 |
2020-07 |
5-methoxytryptophan: An arsenal against vascular injury and inflammation |
- |
|
| [劉俊揚] 期刊論文 |
2020-04-24 |
Expression of Nik-related kinase in smooth muscle cells attenuates vascular inflammation and intimal hyperplasia |
- |
|
| [張俊彥] 期刊論文 |
2020-04-02 |
MiR-30a and miR-379 modulate retinoic acid pathway by targeting DNA methyltransferase 3B in oral cancer |
- |
|
| [伍素瑩] 期刊論文 |
2020-02-10 |
Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors |
- |
|
| [郭呈欽] 期刊論文 |
2020-01 |
Cancer-derived succinate promotes macrophage polarization and cancer metastasis via succinate receptor |
- |
|
| [郭靜娟] 期刊論文 |
2019-12-24 |
ERK activation modulates cancer stemness and motility of a novel mouse oral squamous cell carcinoma cell line |
- |
|
| [郭呈欽] 期刊論文 |
2019-12 |
Vanadium derivative exposure promotes functional alterations of VSMCs and consequent atherosclerosis via ROS/p38/NF-kappaB-Mediated IL-6 Production |
- |
|
| [蔣維棠] 期刊論文 |
2019-12 |
Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia |
- |
|
| [林秀芳] 期刊論文 |
2019-10-09 |
Tryptophan metabolite 5-methoxytryptophan ameliorates arterial denudation-induced intimal hyperplasia via opposing effects on vascular endothelial and smooth muscle cells |
- |
|
| [王淑麗] 期刊論文 |
2019-09 |
Urinary concentration correction methods for arsenic, cadmium, and mercury: A systematic review of practice-based evidence |
- |
|
| [郭靜娟] 期刊論文 |
2019-08 |
Melatonin promotes neuroblastoma cell differentiation by activating hyaluronan synthase 3-induced mitophagy |
- |
|
| [郭呈欽] 會議論文/會議摘要 |
2019-08 |
TLR2 promotes vsmc calcification via the concerted actions of OPG suppression and IL-6-mediated rankl induction |
- |
|
| [林嬪嬪] 期刊論文 |
2019-07 |
Persistent elevation of blood pressure by ambient coarse particulate matter after recovery from pulmonary inflammation in mice |
- |
|
| [褚志斌] 期刊論文 |
2019-07 |
Investigation of the relationship between non-ketotic hyperglycemia and hemichorea-hemiballism: A case report |
- |
|
| [翁紹華] 會議論文/會議摘要 |
2019-07 |
Use of integrated genomic analyses in patient-derived tumor model to discover new clinical indications for the multikinase inhibitor drug candidate, DBPR216 |
- |
|
| [王淑麗] 期刊論文 |
2019-05 |
Type 2 diabetes occurrence and mercury exposure – From the National Nutrition and Health Survey in Taiwan |
- |
|
| [夏興國] 會議論文/會議摘要 |
2019-05 |
A novel mechanism of miRNA-mediated CBX8 associated with tumorigenesis in head and neck squamous cell carcinoma |
- |
|
| [郭呈欽] 期刊論文 |
2019-03 |
TLR2 promotes vascular smooth muscle cell chondrogenic differentiation and consequent calcification via the concerted actions of osteoprotegerin suppression and IL-6-mediated RANKL induction |
- |
|
| [劉俊揚] 期刊論文 |
2019-02-01 |
Cordycepin suppresses endothelial cell proliferation, migration, angiogenesis, and tumor growth by regulating focal adhesion kinase and p53 |
- |
|
| [郭靜娟] 期刊論文 |
2018-12 |
Ubiquitin-conjugating enzyme E2 B regulates the ubiquitination of O(6)-methylguanine-DNA methyltransferase and BCNU sensitivity in human nasopharyngeal carcinoma cells |
- |
|
| [郭靜娟] 會議論文/會議摘要 |
2018-12 |
Establishment and characterization of novel syngeneic oral squamous cell carcinoma mouse cell lines |
- |
|
| [王淑麗] 期刊論文 |
2018-09 |
Early-life arsenic exposure promotes atherogenic lipid metabolism in adolescence: A 15-year birth cohort follow-up study in central Taiwan |
- |
|
| [伍焜玉] 期刊論文 |
2018-07 |
Restoration of hydroxyindole O-methyltransferase levels in human cancer cells induces a tryptophan metabolic switch and attenuates cancer progression |
- |
|
| [翁紹華] 會議論文/會議摘要 |
2018-07 |
4-Bromophenylhydrazinyl benzenesulfonylphenylureas inhibit indoleamine 2,3-dioxygenase in vitro and in vivo |
- |
|
| [謝興邦] 會議論文/會議摘要 |
2018-07 |
Clinical candidate DBPR112: A novel epidermal growth factor receptor inhibitor as a promising treatment for non-small cell lung cancer |
- |
|
| [郭靜娟] 會議論文/會議摘要 |
2018-07 |
Blockage of EGFR signaling repurposes tumor metabolism through suppression of glycolysis and Kreb cycle in head and neck cancer |
- |
|
| [張俊彥] 期刊論文 |
2018-06-15 |
2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition [Erratum: Organic and Biomolecular Chemistry. 2016 Jan;14(2):716-723.] |
- |
|
| [翁紹華] 期刊論文 |
2018-04 |
4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy |
- |
|
| [張俊彥] 期刊論文 |
2018-03-28 |
Novel microtubule inhibitor MPT0B098 inhibits hypoxia-induced epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma |
- |
|
| [劉俊揚] 會議論文/會議摘要 |
2018-01 |
Cordycepin suppresses angiogenesis through regulation of FAK and p53 signaling |
- |
|
| [郭靜娟] 期刊論文 |
2017-12 |
Enhanced B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II poison-resistant cancer cells |
- |
|
| [王淑麗] 期刊論文 |
2017-09 |
The decline in kidney function with chromium exposure is exacerbated with co-exposure to lead and cadmium |
- |
|
| [王淑麗] 期刊論文 |
2017-08-01 |
The association of arsenic metabolism with cancer, cardiovascular disease, and diabetes: A systematic review of the epidemiological evidence |
- |
|
| [郭靜娟] 期刊論文 |
2017-08 |
Hypoxia-induced downregulation of DUSP-2 phosphatase drives colon cancer stemness |
- |
|
| [謝興邦] 期刊論文 |
2017-07 |
Drug repurposing for chronic myeloid leukemia: In silico and in vitro investigation of DrugBank database for allosteric Bcr-Abl inhibitors |
- |
|
| [李秀珠] 期刊論文 |
2017-07 |
Design, synthesis, and evaluation of thiazolidine-2,4-dione derivatives as a novel class of glutaminase inhibitors |
- |
|
| [郭呈欽] 期刊論文 |
2017-06-10 |
Benzodiazepine and Z-drug use and risk of pneumonia in patients with chronic kidney disease: A population-based nested case-control study |
- |
|
| [張中和] 期刊論文 |
2017-06-07 |
Urinary glycated uromodulin in diabetic kidney disease |
- |
|
| [伍焜玉] 期刊論文 |
2017-05 |
Reply to letter: "5-Methoxytryptophan: A promising early marker for predicting post-myocardial infarction heart failure" |
- |
|
| [譚澤華] 期刊論文 |
2017-02 |
Dual-specificity phosphatase 6 deficiency regulates gut microbiome and transcriptome response against diet-induced obesity in mice |
- |
|
| [謝興邦] 期刊論文 |
2016-12 |
Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation |
- |
|
| [洪明秀] 會議論文/會議摘要 |
2016-12 |
Phenyl benzenesulfonylhydrazides: Selective indoleamine 2,3-dioxygenase inhibitors with potent in vivo pharmacodynamic activity and antitumor efficacy |
- |
|
| [伍焜玉] 期刊論文 |
2016-11-01 |
5-methoxytryptophan is a potential marker for post-myocardial infarction heart failure - a preliminary approach to clinical utility |
- |
|
| [郭呈欽] 期刊論文 |
2016-11 |
sn-1,2-diacylglycerols protect against lethal endotoxemia by controlling systemic inflammation |
- |
|
| [林秀芳] 期刊論文 |
2016-09-08 |
Heme oxygenase-1 deficiency exacerbates angiotensin II-induced aortic aneurysm in mice |
- |
|
| [洪文俊] 期刊論文 |
2016-08-31 |
The oncometabolite R-2-hydroxyglutarate activates NF-kappa B-dependent tumor-promoting stromal niche for acute myeloid leukemia cells |
- |
|
| [郭呈欽] 期刊論文 |
2016-08-24 |
TLR4-activated MAPK-IL-6 axis regulates vascular smooth muscle cell function |
- |
|
| [張俊彥] 期刊論文 |
2016-08 |
Desferal regulates hCtr1 and transferrin receptor expression through Sp1 and exhibits synergistic cytotoxicity with platinum drugs in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo |
- |
|
| [郭呈欽] 會議論文/會議摘要 |
2016-08 |
Toll-like receptor 2 promotes vascular calcification via the chondrogenic transdifferentiation of vascular smooth muscle cells |
- |
|
| [夏興國] 期刊論文 |
2016-07-01 |
MPT0B098, a microtubule inhibitor, suppresses JAK2/STAT3 signaling pathway through modulation of SOCS3 stability in oral squamous cell carcinoma |
- |
|
| [郭呈欽] 期刊論文 |
2016-07 |
Endothelium-derived 5-methoxytryptophan is a circulating anti-inflammatory molecule that blocks systemic inflammation |
- |
|
| [林嬪嬪] 期刊論文 |
2016-07 |
Changes of serum amino acid profiles by an epidermal growth factor receptor mutation and benzo[a]pyrene in mouse lung tumorigenesis |
- |
|
| [林秀芳] 期刊論文 |
2016-05-05 |
A novel protective function of 5-Methoxytryptophan in vascular injury |
- |
|
| [郭呈欽] 期刊論文 |
2016-05 |
TLR4 induces CREB-mediated IL-6 production via upregulation of F-spondin to promote vascular smooth muscle cell migration |
- |
|
| [伍焜玉] 期刊論文 |
2016-04-29 |
Inhibition of cancer cell epithelial mesenchymal transition by normal fibroblasts via production of 5-methoxytryptophan |
- |
|
| [伍焜玉] 期刊論文 |
2016-03-22 |
Endothelium-derived 5-methoxytryptophan protects endothelial barrier function by blocking p38 MAPK activation |
- |
|
| [劉誠珍] 期刊論文 |
2016-02 |
Differential modulation of methamphetamine-mediated behavioral sensitization by overexpression of Mu opioid receptors in nucleus accumbens and ventral tegmental area |
- |
|
| [張俊彥] 期刊論文 |
2016-01 |
2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition |
- |
|
| [翁紹華] 期刊論文 |
2016-01 |
Phenyl benzenesulfonylhydrazides exhibit selective Indoleamine 2,3-Dioxygenase inhibition with potent in vivo pharmacodynamic activity and antitumor efficacy |
- |
|
| [劉俊揚] 期刊論文 |
2015-12 |
Rho-associated kinase inhibitors promote the cardiac differentiation of embryonic and induced pluripotent stem cells |
- |
|
| [郭靜娟] 期刊論文 |
2015-12 |
Novel oxime-bearing coumarin derivatives act as potent Nrf2/ARE activators in vitro and in mouse model |
- |
|
| [郭呈欽] 期刊論文 |
2015-10 |
ADP-ribosylation factor 3 mediates cytidine-phosphate-guanosine oligodeoxynucleotide-induced responses by regulating toll-like receptor 9 trafficking |
- |
|
| [張俊彥] 期刊論文 |
2015-09 |
O6-Methylguanine DNA methyltransferase repairs platinum-DNA adducts following cisplatin treatment and predicts prognoses of nasopharyngeal carcinoma |
- |
|
| [郭靜娟] 期刊論文 |
2015-08 |
Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes |
- |
|
| [郭靜娟] 期刊論文 |
2015-08 |
Novel Nrf2/ARE activator, trans-coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38alpha/MAPKAPK-2 and PK-N3 signaling pathway |
- |
|
| [謝興邦] 會議論文/會議摘要 |
2015-08 |
Optimization of furanopyrimidine-based kinase inhibitors: Identification of a BTK kinase inhibitor for the treatment of B cell lymphoma |
- |
|
| [楊良棟] 期刊論文 |
2015-06-24 |
N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting |
- |
|
| [郭靜娟] 期刊論文 |
2015-05 |
Mechanistic basis of a combination D-penicillamine and platinum drugs synergistically inhibits tumor growth in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo |
- |
|
| [郭靜娟] 會議論文/會議摘要 |
2015-05 |
Enhanced antitumor activity of rapamycin and genipin, a UCP-2 inhibitor, in lung cancer |
- |
|
| [伍焜玉] 會議論文/會議摘要 |
2015-05 |
Control of lupus by novel tryptophan metabolite 5-methoxytryptophan |
- |
|
| [郭呈欽] 會議論文/會議摘要 |
2015-05 |
5-methoxytryptophan is a circulating anti-inflammatory molecule that controls lipopolysaccharide-induced systemic inflammation and sepsis |
- |
|
| [何英剛(2006-2011)] 期刊論文 |
2015-03-06 |
Buprenorphine, methadone, and morphine treatment during pregnancy: Behavioral effects on the offspring in rats |
- |
|
| [郭靜娟] 期刊論文 |
2015-01 |
Two new labdane-type diterpene acids from the wood of cunninghamia konishii |
- |
|
| [謝興邦] 會議論文/會議摘要 |
2014-11 |
Discovery of multiple kinases inhibitors, DBPR114, as the novel anti-cancer agent |
- |
|
| [夏興國] 會議論文/會議摘要 |
2014-11 |
Cytokine induces MIR-424 expression and modulates SOCS2/STAT5 signaling pathway in oral cancer |
- |
|
| [張俊彥] 會議論文/會議摘要 |
2014-10 |
Copper-chelator exerts synergistic interaction with platinum drugs through modulating copper transporters in oxaliplatin-resistant human gastric cancer cell |
- |
|
| [張俊彥] 期刊論文 |
2014-09 |
Concise syntheses of 7-anilino-indoline-N-benzenesulfonamides as antimitotic and vascular disrupting agents |
- |
|
| [郭靜娟] 期刊論文 |
2014-08 |
Two new acidic diterpenoids from the heartwood of Pinus massoniana LAMB |
- |
|
| [蔡坤志] 期刊論文 |
2014-07 |
Cancer/stroma interplay via cyclooxygenase-2 and indoleamine 2,3-dioxygenase promotes breast cancer progression |
- |
|
| [張俊彥] 期刊論文 |
2014-05 |
Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells |
- |
|
| [郭靜娟] 會議論文/會議摘要 |
2014-05 |
High expression of Hsp90-beta and GRP 94 association with poor survival in resected non-small cell lung cancer patients |
- |
|
| [張俊彥] 期刊論文 |
2014-04 |
Antimitotic and vascular disrupting agents: 2-hydroxy-3,4,5-trimethoxybenzophenones |
- |
|
| [郭呈欽] 會議論文/會議摘要 |
2014-04 |
Proliferating fibroblasts suppress cancer cell epithelial-to-mesenchymal transition (EMT) and migration via control inhibition of p300 HAT activation by 5-methoxytryptophan |
- |
|
| [伍焜玉] 期刊論文 |
2014-02 |
Quiescent and proliferative fibroblasts exhibit differential p300 HAT activation through control of 5-methoxytryptophan production |
- |
|
| [郭靜娟] 期刊論文 |
2013-12 |
Diterpenoids from the wood of Cunninghamia konishii |
- |
|
| [伍焜玉] 會議論文/會議摘要 |
2013-12 |
Fibroblasts suppress cancer cell p300 HAT activation and cell migration via 5-methoxytryptophan production |
- |
|
| [伍焜玉] 會議論文/會議摘要 |
2013-12 |
Quiescent and proliferative fibroblasts exhibit differential p300 HAT activation through control of 5-methoxytryptophan production |
- |
|
| [謝興邦] 專利 |
2013-11-21 |
治療癌症的醫藥組成物 |
- |
|
| [顏伶汝] 期刊論文 |
2013-11 |
Overexpression of galectin-9 in islets prolongs grafts survival via downregulation of Th1 responses |
- |
|
| [黃嘯谷] 會議論文/會議摘要 |
2013-11 |
Aryl hydrocarbon receptor (AhR) controls cellular redox and metabolic homeostasis in mast cells |
- |
|
| [郭靜娟] 期刊論文 |
2013-10 |
Histone deacetylase inhibition improved cardiac functions with direct antifibrotic activity in heart failure |
- |
|
| [郭靜娟] 期刊論文 |
2013-10 |
Gene expression profiling for analysis acquired oxaliplatin resistant factors in human gastric carcinoma TSGH-S3 cells: The role of IL-6 signaling and Nrf2/AKR1C axis identification |
- |
|
| [張俊彥] 期刊論文 |
2013-09 |
MPT0B098, a novel microtubule inhibitor that destabilizes the hypoxia-inducible factor-1α mrna through decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR [Erratum: Molecular Cancer Therapeutics. 2013 Jul;12(7):1202-1212.] |
- |
|
| [張俊彥] 期刊論文 |
2013-09 |
Furanylazaindoles: Potent anticancer agents in vitro and in vivo |
- |
|
| [劉柯俊] 期刊論文 |
2013-07-19 |
Surface alpha-enolase promotes extracellular matrix degradation and tumor metastasis and represents a new therapeutic target |
- |
|
| [張俊彥] 期刊論文 |
2013-07 |
MPT0B098, a novel microtubule inhibitor that destabilizes the hypoxia-inducible factor-1 alpha mRNA through decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR |
- |
|
| [郭靜娟] 期刊論文 |
2013-06 |
Heart failure and angiotensin II modulate atrial Pitx2c promotor methylation |
- |
|
| [郭靜娟] 期刊論文 |
2013-06 |
Aconitamide, a novel alkaloid from the roots of aconitum carmichaeli |
- |
|
| [郭靜娟] 期刊論文 |
2013-06 |
Two new lignans from the wood of cunninghamia konishii |
- |
|
| [劉紹興] 期刊論文 |
2013-04 |
Fine particulate air pollution and hospital admissions for myocardial infarction in a subtropical city: Taipei, Taiwan |
- |
|
| [郭靜娟] 期刊論文 |
2013-03-15 |
Analgesic and anti-inflammatory bioactivities of eburicoic acid and dehydroeburicoic acid isolated from antrodia camphorata on the inflammatory mediator expression in mice |
- |
|
| [張俊彥] 期刊論文 |
2013-03-12 |
A novel synthetic microtubule inhibitor, MPT0B214 exhibits antitumor activity in human tumor cells through mitochondria-dependent intrinsic pathway |
- |
|
| [其他] 期刊論文 |
2013-03 |
Parity, age at first birth, and risk of death from chronic rend failure: A cohort study of parous women in Taiwan |
- |
|
| [其他] 期刊論文 |
2013-01-16 |
The risk of upper gastrointestinal bleeding in patients treated with hemodialysis: A population-based cohort study |
- |
|
| [張俊彥] 期刊論文 |
2012-12 |
Arginine deprivation as a new treatment strategy for head and neck cancer |
- |
|
| [謝興邦] 期刊論文 |
2012-12 |
An efficient, mild and scalable synthesis of bioactive compounds containing the angelicin scaffold |
- |
|
| [郭靜娟] 期刊論文 |
2012-12 |
Application of Suzuki arylation, Sonogashira ethynylation and Rosenmund-von Braun cyanation in the exploration of substitution effects on the anticancer activity of 2-aroylquinolines |
- |
|
| [伍焜玉] 期刊論文 |
2012-11 |
TLR 2 induces vascular smooth muscle cell migration through cAMP response element-binding protein-mediated interleukin-6 production |
- |
|
| [其他] 期刊論文 |
2012-11 |
Death of a son is associated with risk of suicide among parous women in Taiwan: A nested case-control study |
- |
|
| [郭靜娟] 期刊論文 |
2012-10 |
Adlay (薏苡 yi yi; “soft-shelled job’s tears”, the seeds of Coix lachryma-jobi L. var. ma-yuen Stapf) is a potential cancer chemopreventive agent toward multistage carcinogenesis processes |
- |
|
| [其他] 期刊論文 |
2012-09 |
Statin use and the risk of bladder cancer: A population-based case-control study |
- |
|
| [伍焜玉] 期刊論文 |
2012-08-14 |
Control of cyclooxygenase-2 expression and tumorigenesis by endogenous 5-methoxytryptophan |
- |
|
| [其他] 期刊論文 |
2012-07 |
Statin use and the risk of kidney cancer: A population-based case-control study |
- |
|
| [郭呈欽] 期刊論文 |
2012-07 |
TLR9-mediated ARF6 activation is involved in advancing CpG ODN cellular uptake |
- |
|
| [伍焜玉] 期刊論文 |
2012-06 |
Lobe-specific calcium binding in calmodulin regulates endothelial nitric oxide synthase activation |
- |
|
| [張俊彥] 期刊論文 |
2012-04 |
Targeting cathepsin S induces tumor cell autophagy via the EGFR-Erk signaling pathway |
- |
|
| [其他] 期刊論文 |
2012-03 |
Risk of herpes zoster in patients treated with long-term hemodialysis: A matched cohort study |
- |
|
| [郭靜娟] 期刊論文 |
2012-03 |
4-Ketopinoresinol, a novel naturally occurring ARE activator, induces the Nrf2/HO-1 axis and protects against oxidative stress-induced cell injury via activation of PI3K/AKT signaling |
- |
|
| [王聲昌] 期刊論文 |
2012-03 |
Genome-wide association study of treatment refractory schizophrenia in Han Chinese |
- |
|
| [郭呈欽] 期刊論文 |
2012-02 |
Pivotal role of ADP-ribosylation factor 6 in toll-Like receptor 9-mediated immune signaling |
- |
|
| [郭靜娟] 期刊論文 |
2011-12-22 |
5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2 |
- |
|
| [張俊彥] 期刊論文 |
2011-12-15 |
Combination of arsenic trioxide and BCNU synergistically triggers redox-mediated autophagic cell death in human solid tumors |
- |
|
| [謝興邦] 專利 |
2011-11-15 |
Coumarin compounds and their use for treating cancer |
- |
|
| [劉界元(2003-2010)] 期刊論文 |
2011-11-01 |
Proteomic analysis of gemcitabine-induced drug resistance in pancreatic cancer cells |
- |
|
| [郭靜娟] 期刊論文 |
2011-10 |
Novel terpenoids from calocedrus macrolepis var. formosana |
- |
|
| [張俊彥] 期刊論文 |
2011-09 |
Synthesis and biological evaluation of 1-(4′-Indolyl and 6′-Quinolinyl) indoles as a new class of potent anticancer agents |
- |
|
| [郭靜娟] 會議論文/會議摘要 |
2011-09 |
DNA repair enzyme, O6-methylguanine DNa methyltransferase, modulates therapeutic efficacy of platinum drugs with radiation and its clinical significance |
- |
|
| [郭靜娟] 期刊論文 |
2011-06 |
Antimutagenic constituents of adlay ( Coix lachryma-jobi L. var. ma-yuen Stapf) with potential cancer chemopreventive activity |
- |
|
| [郭靜娟] 期刊論文 |
2011-06 |
Cytotoxic steroidal saponins from agave sisalana |
- |
|
| [謝興邦] 期刊論文 |
2011-04-28 |
Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents |
- |
|
| [郭靜娟] 期刊論文 |
2011-04 |
Concise syntheses of N-aryl-5,6,7-trimethoxyindoles as antimitotic and vascular disrupting agents: application of the copper-mediated Ullmann-type arylation |
- |
|
| [夏和雄(1996-2012)] 會議論文/會議摘要 |
2011-04 |
Activation of Akt/FoxO axis confers resistance to cisplatin in human nasopharyngeal carcinomas |
- |
|
| [郭靜娟] 會議論文/會議摘要 |
2011-04 |
Activation of NRF2/ABCC1 axis confers resistance to topoisomerase II poisons in human oral malignancies |
- |
|
| [張俊彥] 會議論文/會議摘要 |
2011-04 |
MPT0B098, a novel microtubule inhibitor, displays potent anti-angiogenic activity via destabilizing hypoxia-inducible factor-1alpha mRNA |
- |
|
| [張俊彥] 會議論文/會議摘要 |
2011-04 |
Targeting cathepsin S induces tumor cell autophagy via the EGFR-ERK signaling pathway |
- |
|
| [張俊彥] 期刊論文 |
2011-03-07 |
Synthesis and biological evaluation of 4-aroyl-6,7,8-trimethoxyquinolines as a novel class of anticancer agents |
- |
|
| [陳立宗] 期刊論文 |
2011-03-07 |
2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors |
- |
|
| [郭靜娟] 期刊論文 |
2011-01-26 |
Labdanecaryophyllic acid, a novel cytotoxic C35 terpenoid from Calocedrus macrolepis var. formosana |
- |
|
| [郭靜娟] 期刊論文 |
2010-08 |
Synthesis and biological evaluation of 7-arylindoline-1-benzenesulfonamides as a novel class of potent anticancer agents |
- |
|
| [郭靜娟] 期刊論文 |
2010-06-18 |
Cytotoxic C35 terpenoid cryptotrione from the bark of cryptomeria japonica |
- |
|
| [張文祥] 期刊論文 |
2010-06 |
Design and synthesis of alpha-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis |
- |
|
| [張俊彥] 期刊論文 |
2010-05 |
Chamaecypanone C, a novel skeleton microtubule inhibitor, with anticancer activity by trigger caspase 8-Fas/FasL dependent apoptotic pathway in human cancer cells |
- |
|
| [張俊彥] 期刊論文 |
2010-04 |
Arecoline arrests cells at prometaphase by deregulating mitotic spindle assembly and spindle assembly checkpoint: Implication for carcinogenesis |
- |
|
| [張俊彥] 期刊論文 |
2010-03-11 |
5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors |
- |
|
| [劉俊揚] 期刊論文 |
2010-01-30 |
Bortezomib suppresses focal adhesion kinase expression via interrupting nuclear factor-kappa B |
- |
|
| [郭靜娟] 期刊論文 |
2009-11-01 |
Effects of drying and extrusion on colour, chemical composition, antioxidant activities and mitogenic response of spleen lymphocytes of sweet potatoes |
- |
|
| [謝興邦] 期刊論文 |
2009-08-13 |
Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach |
- |
|
| [郭呈欽] 期刊論文 |
2009-08 |
F-spondin plays a critical role in murine neuroblastoma survival by maintaining IL-6 expression |
- |
|
| [伍素瑩] 期刊論文 |
2009-07-23 |
Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity |
- |
|
| [張俊彥] 期刊論文 |
2009-07-03 |
Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers |
- |
|
| [郭靜娟] 會議論文/會議摘要 |
2009-05 |
HQO-0601, an amide-containg 3, 4-dihydroquinolinone derivative, against human hematologic malignancies through inhibition of mammalian target of repamycin signaling pathway |
- |
|
| [張俊彥] 期刊論文 |
2009-04-17 |
Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents |
- |
|
| [謝興邦] 期刊論文 |
2008-12-25 |
Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents |
- |
|
| [張俊彥] 期刊論文 |
2008-08 |
Transcriptional repression of O-6-methylguanine DNA methyltransferase gene rendering cells hypersensitive to N,N '-bis(2-chloroethyl)-N-nitrosurea in camptothecin-resistant cells |
- |
|
| [張俊彥] 期刊論文 |
2008-07-24 |
Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors |
- |
|
| [郭呈欽] 期刊論文 |
2008-05-01 |
The roles of Tyr91 and Lys162 in general acid-base catalysis in the pigeon NADP+-dependent malic enzyme |
- |
|
| [張俊彥] 期刊論文 |
2008-02 |
A novel peroxisome proliferator-activated receptor alpha/gamma agonist, BPR1H0101, inhibits topoisomerase II catalytic activity in human cancer cells |
- |
|
| [張俊彥] 期刊論文 |
2007-11-15 |
Tamoxifen accelerates proteasomal degradation of O-6-methylguanine DNA methyltransferase in human cancer cells |
- |
|
| [梁啟銘(2006-2007)] 期刊論文 |
2007-11 |
Effects of CpG-B ODN on the protein expression profile of swine PBMC |
- |
|
| [張俊彥] 期刊論文 |
2007-10 |
A novel oral indoline-sulfonamide agent, N-[1-(4-Methoxy-benzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-Isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule |
- |
|
| [張俊彥] 期刊論文 |
2007-09-06 |
4-and 5-aroylindoles as novel classes of potent antitubulin agents |
- |
|
| [張俊彥] 期刊論文 |
2007-07-31 |
Combined modalities of resistance in an oxaliplatin-resistant human gastric cancer cell line with enhanced sensitivity to 5-fluorouracil |
- |
|
| [梁啟銘(2006-2007)] 期刊論文 |
2007-05 |
Involvement of heat shock protein (Hsp)90 beta but not Hsp90 alpha in antiapoptotic effect of CpG-B oligodeoxynucleotide |
- |
|
| [郭靜娟] 期刊論文 |
2007-02-26 |
Cytotoxic and novel skeleton compounds from the heartwood of Chamaecyparis obtusa var. formosana |
- |
|
| [郭靜娟] 期刊論文 |
2007-01 |
D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation |
- |
|
| [郭靜娟] 期刊論文 |
2006-11-27 |
C-35 terpenoids from the bark of Calocedrus macrolepis var. formosana with activity against human cancer cell lines |
- |
|
| [張俊彥] 期刊論文 |
2006-11-16 |
7-aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents |
- |
|
| [陳立宗] 會議論文/會議摘要 |
2006-11 |
Combined modalities of resistance in an oxaliplaitin-resistant human gastric cancer cell line with enhanced sensitivity |
- |
|
| [張俊彥] 會議論文/會議摘要 |
2006-11 |
D-501036, a novel selenophene-base triheterocycle derivative exhibits potent in vitro and in vivo anti-tumoral activity, which involves DNA-damage and ATM activation |
- |
|
| [張俊彥] 會議論文/會議摘要 |
2006-11 |
Tamoxifen induces degradation of the o6-methylguanine DNA methyltransferase protein via the ubiquitin-dependent proteosome pathway in human cancer cells |
- |
|
| [郭靜娟] 期刊論文 |
2006-10-19 |
2-amino and 2 '-aminocombretastatin derivatives as potent antimitotic agents |
- |
|
| [謝興邦] 期刊論文 |
2006-10 |
Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents |
- |
|
| [張俊彥] 會議論文/會議摘要 |
2006-02 |
DNA repair enzyme, O-6-methylguanine DNA methyltransferase, modulates cytotoxicity of camptothecin-derived topoisomerase I inhibitors |
- |
|
| [郭靜娟] 期刊論文 |
2005-02 |
Cytotoxic triterpenes from the aerial roots of Ficus microcarpa |
- |
|
| [郭靜娟] 期刊論文 |
2005-01 |
Four new 6-Nor-5(6 →7)abeo-abietane type diterpenes and antitumoral cytotoxic diterpene constituents from the bark of Taiwania cryptomerioides |
- |
|
| [李秀珠] 會議論文/會議摘要 |
2004-09 |
Drug design of BPR0L075 as an anticancer agent |
- |
|
| [張俊彥] 期刊論文 |
2004-07-15 |
A novel bis-benzylidenecyclopentanone derivative, BPR0Y007, inducing a rapid caspase activation involving upregulation of Fas (CD95/APO-1) and wild-type p53 in human oral epidermoid carcinoma cells |
- |
|
| [張俊彥] 期刊論文 |
2004-07-01 |
BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo |
- |
|
| [李秀珠] 會議論文/會議摘要 |
2004-07 |
Drug design for BPR0L075 as an anticancer agent |
- |
|
| [黃奇英(1998-2005)] 期刊論文 |
2004-02 |
Surfection: a new platform for transfected cell arrays |
- |
|
| [陳立宗] 期刊論文 |
2004-01-01 |
Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and -resistant human tumor cells |
- |
|
| [張俊彥] 期刊論文 |
2004-01 |
Three new oleanane-type triterpenes from Ludwigia octovalvis with cytotoxic activity against two human cancer cell lines |
- |
|
| [張俊彥] 期刊論文 |
2002-10-09 |
2,2 '-diphenyl-1-picrylhydrazyl radical-scavenging active components from adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) hulls |
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