| 2011-07 |
Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) |
Bioorganic and Medicinal Chemistry. 2011 Jul;19(14):4173-4182 . |
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| 2011-05 |
Quercetin and rutin reduced the bioavailability of cyclosporine from Neoral, an immunosuppressant, through activating P-glycoprotein and CYP 3A4 |
Journal of Agricultural and Food Chemistry. 2011 May;59(9):4644-4648. |
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| 2011-01-13 |
Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes |
Journal of Medicinal Chemistry. 2011 Jan 13;54(1):166-178. |
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| 2011-01 |
BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities |
Cancer Science. 2011 Jan;102(1):182-191. |
|
| 2010-12 |
Discovery of non-glycoside sodium-dependent glucose Co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening |
Journal of Medicinal Chemistry. 2010 Dec;53(24):8770-8774. |
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| 2010-11 |
Self-assembled pH-sensitive nanoparticles: A platform for oral delivery of protein drugs |
Advanced Functional Materials. 2010 Nov;20(21):3695-3700. |
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| 2010-11 |
Do neutrophils play a role in establishing liver abscesses and distant metastases caused by Klebsiella pneumoniae? |
PLoS ONE. 2010 Nov;5(11):Article number e15005. |
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| 2010-10-28 |
Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency |
Journal of Medicinal Chemistry. 2010 Oct 28;53(20):7316-7326. |
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| 2010-09 |
Intravenous paclitaxel against metastasis of human gastric tumors of diffuse type |
Cancer Chemotherapy and Pharmacology. 2010 Sep;66(4):773-783. |
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| 2010-07 |
Antiangiogenic Activities and Cisplatin-combined Antitumor Activities of BPR0L075 |
Anticancer Research. 2010 Jul;30(7):2813-2822. |
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| 2010-06-15 |
(2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV |
Bioorganic and Medicinal Chemistry Letters. 2010 Jun 15;20(12):3596-3600. |
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| 2010-03 |
Sex differences in high-fat diet-induced obesity, metabolic alterations and learning, and synaptic plasticity deficits in mice |
Obesity. 2010 Mar;18(3):463-469. |
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| 2010-03 |
Synthesis and biological activities of 2-Amino-1-arylidenamino imidazoles as orally active anticancer agents |
Journal of Medicinal Chemistry. 2010 Mar;53(6):2409-2417. |
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| 2010-02 |
Antitumor activities and pharmacokinetics of silatecans DB-67 and DB-91 |
Pharmacological Research. 2010 Feb;61(2):108-115. |
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| 2010-02 |
Abnormal expressions of circadian-clock and circadian clock-controlled genes in the livers and kidneys of long-term, high-fat-diet-treated mice |
International Journal of Obesity. 2010 Feb;34(2):227-239. |
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| 2009-10 |
(1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases |
Journal of the Chinese Chemical Society. 2009 Oct;56(5):1048-1055. |
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| 2009-08-13 |
Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach |
Journal of Medicinal Chemistry. 2009 Aug 13;52(15):4941-4945. |
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| 2009-07-23 |
Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity |
Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4221-4233. |
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| 2009-07 |
Effect of taurine supplementation on cytochrome P450 2E1 and oxidative stress in the liver and kidneys of rats with streptozotocin-induced diabetes |
Food and Chemical Toxicology. 2009 Jul;47(7):1703-1709. |
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| 2009-04-01 |
Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2009 Apr 1;19(7):1908-1912. |
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| 2009-04 |
In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery |
Biomaterials. 2009 Apr;30(12):2329-2339. |
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| 2009-03-15 |
Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors |
Bioorganic and Medicinal Chemistry. 2009 Mar 15;17(6):2388-2399. |
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| 2009-03 |
Non-lethal Candida albicans cph1/cph1 efg1/efg1 mutant partially protects mice from systemic infections by lethal wild-type cells |
Mycological Research. 2009 Mar;113(3):388-390. |
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| 2008-11-28 |
Anti-angiogenic action of 5,5-diphenyl-2-thiohydantoin-N10 (DPTH-N10) |
Cancer Letters. 2008 Nov 28;271(2):294-305. |
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| 2008-09 |
Human breast tumor cells express multimodal imaging reporter genes |
Molecular Imaging and Biology. 2008 Sep;10(5):253-263. |
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| 2008-07-09 |
Enhanced oral bioavailability of paclitaxel by D-alpha-tocopheryl polyethylene glycol 400 succinate in mice |
International Journal of Pharmaceutics. 2008 Jul;359(1-2):174-181. |
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| 2008-06 |
Oral delivery of peptide drugs using nanoparticles self-assembled by poly(gamma-glutamic acid) and a chitosan derivative functionalized by trimethylation |
Bioconjugate Chemistry. 2008 Jun;19(6):1248-1255. |
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| 2008-03 |
Decreased expression of UK114 is related to the differentiation status of human hepatocellular carcinoma |
Cancer Epidemiology Biomarkers and Prevention. 2008 Mar;17(3):535-542. |
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| 2008-02-28 |
Shengmai San reduces hepatic lipids and lipid peroxidation in rats fed on a high-cholesterol diet |
Journal of Ethnopharmacology. 2008 Feb;116(1):49-57. |
|
| 2007-08 |
A randomised placebo-controlled trial of a traditional chinese herbal formula in the treatment of primary dysmenorrhoea |
PLoS ONE. 2007 Aug;2(8):Article number e719. |
|
| 2007-07 |
Biotransformation of 6-methoxy-3-(3 ',4 ',5 '-trimethoxy-benzoyl)-1-hindole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes |
Drug Metabolism and Disposition. 2007 Jul;35(7):1042-1049. |
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| 2007-03-14 |
Novel nanoparticles for oral insulin delivery via the paracellular pathway |
Nanotechnology. 2007 Mar;18(10):Article number 105102. |
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| 2007-03-01 |
3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes |
Bioorganic and Medicinal Chemistry Letters. 2007 Mar;17(5):1274-1279. |
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| 2007-03 |
Effects of paclitaxel and doxorubicin in histocultures of hepatocelular carcinomas |
Journal of Biomedical Science. 2007 Mar;14(2):233-244. |
|
| 2007-02-01 |
Development and validation of a liquid chromatography-tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: Application to a pharmacokinetic study |
Journal of Chromatography B. 2007 Feb;846(1-2):162-168. |
|
| 2007-01 |
Preparation and characterization of nanoparticles shelled with chitosan for oral insulin delivery |
Biomacromolecules. 2007 Jan;8(1):146-152. |
|
| 2006-12 |
Pharmacokinetics of anti-SARS-CoV agent niclosamide and its analogs in rats |
Journal of Food and Drug Analysis. 2006 Dec;14(4):329-333. |
|
| 2006-11-25 |
The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes |
Life Sciences. 2006 Nov;79(26):2432-2440. |
|
| 2006-08 |
Impaired phagocytosis of capsular serotypes K1 or K2 Klebsiella pneumoniae in type 2 diabetes mellitus patients with poor glycemic control |
Journal of Clinical Endocrinology and Metabolism. 2006 Aug;91(8):3084-3087. |
|
| 2006-07 |
Non-lethal Candida albicans cph1/cph1 efg1/efg1 transcription factor mutant establishing restricted zone of infection in a mouse model of systemic infection |
International Journal of Immunopathology and Pharmacology. 2006 Jul-Sep;19(3):561-565. |
|
| 2006-06-15 |
Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2006 Jun;16(12):3268-3272. |
|
| 2006-05-04 |
Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities |
Journal of Medicinal Chemistry. 2006 May;49(9):2703-2712. |
|
| 2006-03 |
Paclitaxel-loaded poly(gamma-glutamic acid)-poly(lactide) nanoparticles as a targeted drug delivery system for the treatment of liver cancer |
Biomaterials. 2006 Mar;27(9):2051-2059. |
|
| 2006-03 |
Paclitaxel-loaded poly(gamma-glutamic acid)-poly(lactide) nanoparticles as a targeted drug delivery system against cultured HepG2 cells |
Bioconjugate Chemistry. 2006 Mar;17(2):291-299. |
|
| 2006-01-12 |
2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV |
Journal of Medicinal Chemistry. 2006 Jan;49(1):373-380. |
|
| 2005-12-29 |
Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities |
Journal of Medicinal Chemistry. 2005 Dec;48(26):8194-8208. |
|
| 2005-05 |
Loading of a novel angiogenic agent, ginsenoside Rg(1) in an acellular biological tissue for tissue regeneration |
Tissue Engineering. 2005 May;11(5-6):835-846. |
|
| 2005-04 |
A natural compound (ginsenoside Re) isolated from Panax ginseng as a novel angiogenic agent for tissue regeneration |
Pharmaceutical Research. 2005 Apr;22(4):636-646. |
|
| 2005-03 |
Preparation of nanoparticles composed of chitosan/poly-gamma-glutamic acid and evaluation of their permeability through Caco-2 cells |
Biomacromolecules. 2005 Mar;6(2):1104-1112. |
|
| 2004-08-10 |
Inhibition of human vascular endothelial cells proliferation by terbinafine |
International Journal of Cancer. 2004 Aug;111(1):51-59. |
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