Collection Patents [0/18] Periodical Articles [157/157] Conference Papers/Meeting Abstract [23/37] Siblings Su-Ying Wu [52/65] Others [58/60] Kak-Shan Shia [76/98] Yueh Andrew Yueh [29/32] Chung-Ming Chang [7/9] Jang-Yang Chang [18/18] Chun-Ping Chang [21/26] John Tsu-An Hsu [170/215] Shiow-Ju Lee [75/105] Jinq-Chyi Lee [23/24] Shu-Yu Lin [19/20] Ming-Shiu Hung [31/40] Shiow-Lin Pan(2009-2013) [16/17] Wen-Chieh Wang [13/15] Hung-Jung Wang [7/7] Chuan Shih(2014-2017) [35/39] Chun-Wei Tung [23/23] Ya-Hui Chi [21/25] Shau-Hua Ueng [22/24] Hong Zhuang [1/1] Shiu-Hwa Yeh [24/25] Teng-Kuang Yeh [133/152] Weir-Torn Jiaang [41/66] Hsing-Pang Hsieh [171/231] Yu-Sheng Chao(2002-2013) [120/212] Ching-Chuan Kuo [49/55] Lun Kelvin Tsou [28/29] Jyh-Haur Chern [31/52] Xin Chen(2002-2015) [53/67] Wan-Ching Yen [6/7] Ming-Chu Hsu(1997-2001) [3/10] Shu-Jung Chen(1998-2001) [3/11] Hua-Chien Chen(1997-2001) [9/9] Community Statistics Item counts issued in 3 years:19(8.96%) Items With Fulltext:180(84.91%) Download counts of the item Download times greater than 0:180(100.00%) Download times greater than 100:176(97.78%) Total Bitstream Download Counts:97564(1.82%) Last Update: 2024-12-01 08:25 Top Upload Loading... Top Download Loading... Recent Submissions DBPR116, a prodrug of BPRMU191, in ... Discovery of a mu-opioid receptor m... Discovery of a long half-life AURKA... Postfermented tea extract potently ... Natural fucoidans inhibit coronavir... Development of furanopyrimidine-bas... The synergistic inhibition of coron... Omicron-specific mRNA vaccine induc... BPR0C261, an analogous of microtubu... Protective effect of CXCR4 antagoni...

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Showing items 1-50 of 212. (5 Page(s) Totally) 1 2 3 4 5 > >> View [10|25|50] records per page

Date	Title	Relation
2024-10-29	DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration	Journal of Medicinal Chemistry. 2024 Oct 29;Article in Press.
2024-07-17	Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia	Cell Chemical Biology. 2024 Jul 17;Article in Press.
2024-06-01	Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus	Molecular Cancer Therapeutics. 2024 Jun 01;23(6):766-779.
2024-02-16	Postfermented tea extract potently alleviates glucose metabolism disorders in vitro and in vivo	ACS Food Science and Technology. 2024 Feb 16;4(2):479-490.
2023-07-20	Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin	Biochemical Pharmacology. 2023 Jul 20;215:Article number 115688.
2023-02-07	Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer	Journal of Medicinal Chemistry. 2023 Feb 7;66(4):2566-2588.
2023-01-19	The synergistic inhibition of coronavirus replication and induced cytokine production by ciclesonide and the tylophorine-based compound dbq33b [Erratum:Pharmaceutics. 2022 Jul 21;14(7):Article number 1511.]	Pharmaceutics. 2023 Jan 19;15(2):Article number 342.
2022-12-05	Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation	European Journal of Medicinal Chemistry. 2022 Dec 5;243:Article number 114728.
2022-12-02	Omicron-specific mRNA vaccine induced cross-protective immunity against ancestral SARS-CoV-2 infection with low neutralizing antibodies	Journal of Medical Virology. 2022 Dec 2;95:Article number e28370.
2022-11-15	BPR0C261, an analogous of microtubule disrupting agent D-24851 enhances the radiosensitivity of human non-small cell lung cancer cells via p53-dependent and p53-independent pathways	International Journal of Molecular Sciences. 2022 Nov 15;23(22):Article number 14083.
2022-11-01	Peritoneal effluent MicroRNA profile for detection of encapsulating peritoneal sclerosis	Clinica Chimica Acta. 2022 Nov 1;536:45-55.
2022-11	Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone	Bioorganic Chemistry. 2022 Nov;128:Article number 105905.
2022-10-13	Targeting the phosphatidylserine-immune checkpoint with a small-molecule maytansinoid conjugate	Journal of Medicinal Chemistry. 2022 Oct 13;65(19):12802-12824.
2022-10-03	Protective effect of CXCR4 antagonist DBPR807 against ischemia-reperfusion injury in a rat and porcine model of myocardial infarction: Potential adjunctive therapy for percutaneous coronary intervention	International Journal of Molecular Sciences. 2022 Oct 3;23(19):Article number 11730.
2022-07-21	The synergistic inhibition of coronavirus replication and induced cytokine production by ciclesonide and the tylophorine-based compound dbq33b	Pharmaceutics. 2022 Jul 21;14(7):Article number 1511.
2022-06-21	Synthesis and evaluation of small molecule drug conjugates harnessing thioester-linked maytansinoids	Pharmaceutics. 2022 Jun 21;14(7):Article number 1316.
2022-05-02	Furin and TMPRSS2 resistant spike induces robust humoral and cellular immunity against SARS-CoV-2 lethal infection	Frontiers in Immunology. 2022 May 2;13:Article number 872047.
2022-03-02	Discovery of potential neuroprotective agents against paclitaxel-induced peripheral neuropathy	Journal of Medicinal Chemistry. 2022 Mar 2;65(6):4767-4782.
2022-02-15	Click chemistry and multicomponent reaction for linker diversification of zinc dipicolylamine-based drug conjugates	Frontiers in Chemistry. 2022 Feb 15;9:Article number 822587.
2021-12	Implanted islet mass influences the effects of dipeptidyl peptidase-IV inhibitor LAF237 on transplantation outcomes in diabetic mice	Biomedical Journal. 2021 Dec;44(6 Suppl 2):S210-S217.
2021-11-15	Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization	European Journal of Medicinal Chemistry. 2021 Nov 15;224:Article number 113673.
2021-10-14	Discovery of BPR1R024, an orally active and selective CSF1R inhibitor that exhibits antitumor and immunomodulatory activity in a murine colon tumor model	Journal of Medicinal Chemistry. 2021 Oct 14;64(19):14477-14497.
2021-10-01	Engineering nano- and microparticles as oral delivery vehicles to promote intestinal lymphatic drug transport	Advanced Materials. 2021 Oct 01;201:Article number 2104139.
2021-08-13	Remdesivir and cyclosporine synergistically inhibit the human coronaviruses OC43 and SARS-CoV-2	Frontiers in Pharmacology. 2021 Aug 13;12:Article number 706901.
2021-08-01	DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity	Life Sciences. 2021 Aug 1;278:Article number 119574.
2021-08	A noninvasive gut-to-brain oral drug delivery system for treating brain tumors	Advanced Materials. 2021 Aug;33(34):Article number e2100701.
2021-05-19	Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins	Journal of Medicinal Chemistry. 2021 May 19;64(11):7312-7330.
2021-01	BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy	Translational Oncology. 2021 Jan;14(1):Article number 100897.
2021-01	Potent and orally active purine-based fetal hemoglobin inducers for treating Beta-thalassemia and sickle cell disease	European Journal of Medicinal Chemistry. 2021 Jan;209:Article number 112938.
2020-12-14	Inhibition of SARS-CoV-2 by highly potent broad-spectrum anti-coronaviral tylophorine-based derivatives	Frontiers in Pharmacology. 2020 Dec 14;11:Article number 606097.
2020-11	Molecular profiling of afatinib-resistant non-small cell lung cancer cells in vivo derived from mice	Pharmacological Research. 2020 Nov;161:Article number 105183.
2020-10-08	Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery	Scientific Reports. 2020 Oct 8;10:Article number 16771.
2020-10	A bubble bursting-mediated oral drug delivery system that enables concurrent delivery of lipophilic and hydrophilic chemotherapeutics for treating pancreatic tumors in rats	Biomaterials. 2020 Oct;255:Article number 120157.
2020-08-20	Discovery of M protease inhibitors encoded by SARS-CoV-2	Antimicrobial Agents and Chemotherapy. 2020 Aug 20;64(9):e00872-20.
2020-08	Artificial intelligence approach fighting COVID-19 with repurposing drugs	Biomedical Journal. 2020 Aug;43(4):355-362.
2020-08	Repurposing old drugs as antiviral agents for coronaviruses	Biomedical Journal. 2020 Aug;43(4):368-374.
2020-08	BPR6K609: An Aurora kinase inhibitor targeting small cell lung cancer with MYC amplification	Cancer Research. 2020 Aug;80(16):1937.
2020-02-18	Impacts of intralipid on nanodrug abraxane therapy and on the innate immune system	Scientific Reports. 2020 Feb 18;10:Article number 2838.
2019-12	A novel flavivirus entry inhibitor, BP34610, discovered through high-throughput screening with dengue reporter viruses	Antiviral Research. 2019 Dec;172:Article number 104636.
2019-12	Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia	Journal of Medicinal Chemistry. 2019 Dec;62(24):11135-11150.
2019-11-27	Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer	Journal of Medicinal Chemistry. 2019 Nov 27;62(22):10108-10123.
2019-10	Inhibition of Rspo-Wnt pathway facilitates checkpoint blockade therapy by anti-RSPO3 antibody (DBPR117)	Annals of Oncology. 2019 Oct;30(Suppl. 5):191.
2019-09	Effects of boschnaloside from Boschniakia rossica on dysglycemia and islet dysfunction in severely diabetic mice through modulating the action of glucagon-like peptide-1	Phytomedicine. 2019 Sep;62:Article number 152946.
2019-08-27	A dengue virus type 2 (DENV-2) NS4B-interacting host factor, SERP1, reduces DENV-2 production by suppressing viral RNA replication	Viruses. 2019 Aug 27;11(9):Article number 787.
2019-07-11	Linker optimization and therapeutic evaluation of phosphatidylserine-targeting zinc dipicolylamine-based drug conjugates	Journal of Medicinal Chemistry. 2019 Jul 11;62(13):6047-6062.
2019-07	Citronellol induces necroptosis of human lung cancer cells via TNF-alpha pathway and reactive oxygen species accumulation	In Vivo. 2019 Jul-Aug;33(4):1193-1201.
2019-07	Use of integrated genomic analyses in patient-derived tumor model to discover new clinical indications for the multikinase inhibitor drug candidate, DBPR216	Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 4626.
2019-07	BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy	Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 227.
2019-07	An Aurora kinase inhibitor BPR6K471 inhibits tumor growth and reduces the cancer stem cell-like properties of small cell lung cancer	Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 3851.
2019-06-15	Strategies for improving diabetic therapy via alternative administration routes that involve stimuli-responsive insulin-delivering systems	Advanced Drug Delivery Reviews. 2019 Jan 15;139(SI):71-82.

Showing items 1-50 of 212. (5 Page(s) Totally) 1 2 3 4 5 > >> View [10|25|50] records per page