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    Showing items 51-100 of 212. (5 Page(s) Totally)
    << < 1 2 3 4 5 > >>
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    DateTitleRelation
    2013-11-21 治療癌症的醫藥組成物 I415852/2013-11-21
    2013-11-13 Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice Journal of Medicinal Chemistry. 2013 Nov 13;56(24):9920-9933.
    2013-11 BPR0C305, an orally active microtubule-disrupting anticancer agent Anticancer Drugs. 2013 Nov;24(10):1047-1057.
    2013-10-01 喹啉化合物及包含其之治療病毒感染之醫藥組成物 I410245/2013-10-01
    2013-09-27 Pyrrolidine derivatives RU2494094C2/2013-09-27
    2013-09-11 噻吩化合物及其醫藥組成物 I408136/2013-09-11
    2013-08-21 Fused multicyclic compounds as protein kinase inhibitors EP2331530B1/2013-08-21
    2013-08-13 Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors US8507502B2/2013-08-13
    2013-07-16 Dibenzo[f,h]isoquinoline derivatives US8486959B2/2013-07-16
    2013-07-01 做為蛋白質激酶抑制劑之稠合多環化合物 I400242/2013-07-01
    2013-06-28 Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor Journal of Medicinal Chemistry. 2013 Jun 28;56(13):5247-5260.
    2013-06-05 Anticancer oral formulation EP2310363B1/2013-06-05
    2013-06 c-Jun-mediated anti-cancer mechanisms of tylophorine Carcinogenesis. 2013 Jun;34(6):1304-1314.
    2013-06 Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) Bioorganic and Medicinal Chemistry. 2013 Jun;21(11):2856-2867.
    2013-05 Characterization of an efficient dengue virus replicon for development of assays of discovery of small molecules against dengue virus Antiviral Research. 2013 May;98(2):228-241.
    2013-05 Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules Proceedings of the National Academy of Sciences of the United States of America. 2013 May;110(19):E1779-E1787.
    2013-05 Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors Journal of Medicinal Chemistry. 2013 May;56(10):3889-3903.
    2013-04-30 Pyrrolidine derivatives 164613/2013-04-30
    2013-04-13 Exploration of the role of tylophorine E ring in anti-Coronavirus activity-Tylophorine derived dibenzoquinolines impart multi-biological activities as orally active agents FASEB Journal. 2013 Apr 13;27:lb71.
    2013-04-09 Proline derivatives US8415482B2/2013-04-09
    2013-04-07 BPR000K, a novel Aurora kinase inhibitor Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 300-MEDI.
    2013-04-07 3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 87-MEDI.
    2013-04-07 Development drug candidate targeting EGFR kinase: DBPR112 Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 299-MEDI.
    2013-04 Tylophorine induces c-Jun protein accumulation through two discrete prolonged pathways NF-kappaB/PKCdelta/JNK and PI3K/PDK1/PP2A/eEF2 to promote G1 arrest in carcinoma cells FASEB Journal. 2013 Apr;27:lb74.
    2013-04 Identification of a quinone compound inhibits human glutaminase activity and induces autophagy in carcinoma cells FASEB Journal. 2013 Apr;27:lb70.
    2013-04 Design and synthesis of Aurora kinase inhibitors as anticancer agents Abstracts of Papers - American Chemical Society. 2013 Apr;245:Article number 301-MEDI.
    2013-03-27 Thiophene compounds EP2068870/2013-03-27
    2013-02-11 吡咯啉啶化合物 I385163/2013-02-11
    2013-02-11 抗癌口服藥學組成物 I384984/2013-02-11
    2013-02-11 作為酪胺酸激酶抑制劑之稠合雙環及多環嘧啶化合物 I385174/2013-02-11
    2013-02 Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems Antimicrobial Agents and Chemotherapy. 2013 Feb; 57(2):723-733.
    2013-01-15 Imidazol-4-one and imidazole-4-thione compounds US8354442B2/2013-01-15
    2013-01 3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor ChemMedChem. 2013 Jan;8(1):136-148.
    2012-12-13 Synthesis and biological evaluation of tylophorine-derived dibenzoquinolines as orally active agents: Exploration of the role of tylophorine e ring on biological activity Journal of Medicinal Chemistry. 2012 Dec 13;55(23):10363-10377.
    2012-12 An efficient, mild and scalable synthesis of bioactive compounds containing the angelicin scaffold Journal of the Chinese Chemical Society. 2012 Dec;59(12):1548-1554.
    2012-11 BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia European Journal of Cancer. 2012 Nov;48(Suppl. 6):53-54.
    2012-09 Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization ChemMedChem. 2012 Sep;7(9):1546-1550.
    2012-09 Putative tumor metastasis-associated genes in human gastric cancer International Journal of Oncology. 2012 Sep;41(3):1068-1084.
    2012-07-04 噻吩化合物 ZL200780036897.1/2012-07-04
    2012-07 Induction of fatty acid oxidation resists weight gain, ameliorates hepatic steatosis and reduces cardiometabolic risk factors International Journal of Obesity. 2012 Jul;36(7):999-1006.
    2012-06-15 Pyrrolidine derivatives 587911/2012-06-15
    2012-06-12 Treatment of neurodegenerative disorders with thiourea compounds US8198284B2/2012-06-12
    2012-06-07 3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) Bioorganic and Medicinal Chemistry Letters. 2012 Jun 7;22(14):4654-4659.
    2012-06 EGFR and myosin II inhibitors cooperate to suppress EGFR-T790M-mutant NSCLC cells Molecular Oncology. 2012 Jun;6(3):299-310.
    2012-05-11 作為極光激酶抑制劑之稠合雙環嘧啶化合物 I363627/2012-05-11
    2012-04-21 吡咯啉啶化合物 I362388/2012-04-21
    2012-04-11 咪唑啉酮及咪唑啉硫酮衍生物 I361808/2012-04-11
    2012-03-25 Design, synthesis, and SAR studies of duel FLT-3 and Aurora kinase inhibitors Abstracts of Papers - American Chemical Society. 2012 Mar 25;243:Article number 48-MEDI.
    2012-03-20 Fused bicyclic pyrimidine compounds as aurora kinase inhibitors US8138194B2/2012-03-20
    2012-03-01 C型肝炎病毒抑制劑 I359137/2012-03-01

    Showing items 51-100 of 212. (5 Page(s) Totally)
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