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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/9075


    Title: 作為極光激酶抑制劑之稠合雙環嘧啶化合物
    Other Titles: Fused bicyclic pyrimidine compounds as aurora kinase inhibitors
    Authors: Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS
    Contributors: Institute of Biotechnology and Pharmaceutical Research
    Abstract: 本發明係有關於一種式(I)之稠合雙環嘧啶化合物：其中，R1、R3、R4、X1、X2、Y、Z、A、B、C、D、n、以及兩個鍵結定義於本文中。本發明亦揭露一種抑制極光激酶活性的方法，以及一種以這些化合物治療癌症的方法。 Fused bicyclic pyrimidine compounds of formula (I): wherein R1, R3, R4, X1, X2, Y, Z, A, B, C, D, n, and the two bonds are defined herein. Also disclosed are a method for inhibiting Aurora kinase activity and a method for treating cancer with these compounds.
    Date: 2012-05-11
    Relation: I363627/2012-05-11
    Link to: https://twpat1.tipo.gov.tw/tipotwoc/tipotwkm?!!FR_I363627
    Appears in Collections:[謝興邦] 專利
    [徐祖安] 專利
    [伍素瑩] 專利
    [趙宇生(2002-2013)] 專利

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