國家衛生研究院 NHRI:
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 12145/12927 (94%)
造訪人次 : 911942      線上人數 : 1046
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧:
  • 您可在西文檢索詞彙前後加上"雙引號",以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋,建議至進階搜尋限定作者欄位,可獲得較完整資料
  • 進階搜尋
    主頁登入上傳說明關於NHRI管理 到手機版

    子類別

    報告 [0/1]
    專利 [0/9]
    期刊論文 [69/69]
    會議論文/會議摘要 [6/26]

    鄰近社群


    伍素瑩 [52/65]
    其他 [58/60]
    夏克山 [76/98]
    岳嶽 [29/32]
    張仲明 [7/9]
    張俊彥 [18/18]
    張竣評 [21/26]
    徐祖安 [170/215]
    李靜琪 [23/24]
    林書玉 [19/20]
    洪明秀 [31/40]
    潘秀玲(2009-2013) [16/17]
    王文傑 [13/15]
    王鴻俊 [7/7]
    石全(2014-2017) [35/39]
    童俊維 [23/23]
    紀雅惠 [21/25]
    翁紹華 [22/24]
    莊宏 [1/1]
    葉修華 [24/25]
    葉燈光 [133/152]
    蔣維棠 [41/66]
    謝興邦 [171/231]
    趙宇生(2002-2013) [120/212]
    郭靜娟 [49/55]
    鄒倫 [28/29]
    陳志豪 [31/52]
    陳新(2002-2015) [53/67]
    陳炯東 [180/212]
    顏婉菁 [6/7]
    許明珠(1997-2001) [3/10]
    陳淑貞(1998-2001) [3/11]
    陳華鍵(1997-2001) [9/9]

    社群統計


    近3年內發表的文件:5(4.76%)
    含全文筆數:75(71.43%)

    文件下載次數統計
    下載大於0次:75(100.00%)
    下載大於100次:73(97.33%)
    檔案下載總次數:47664(0.89%)

    最後更新時間: 2024-12-01 13:30

    上傳排行

    資料載入中.....

    下載排行

    資料載入中.....

    RSS Feed RSS Feed
    跳至:
    或輸入年份:
    由新到舊排序 由最舊的開始

    顯示項目1-50 / 105. (共3頁)
    1 2 3 > >>
    每頁顯示[10|25|50]項目

    日期題名關聯
    2024-02-15 Vitamin B12 inhibits peptidylarginine deiminases and ameliorates rheumatoid arthritis in CAIA mice Biochemical and Biophysical Research Communications. 2024 Feb 15;704:Article number 149668.
    2023-07-20 Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin Biochemical Pharmacology. 2023 Jul 20;215:Article number 115688.
    2023-01-19 The synergistic inhibition of coronavirus replication and induced cytokine production by ciclesonide and the tylophorine-based compound dbq33b [Erratum:Pharmaceutics. 2022 Jul 21;14(7):Article number 1511.] Pharmaceutics. 2023 Jan 19;15(2):Article number 342.
    2022-07-21 The synergistic inhibition of coronavirus replication and induced cytokine production by ciclesonide and the tylophorine-based compound dbq33b Pharmaceutics. 2022 Jul 21;14(7):Article number 1511.
    2022-02-17 Tyrphostin AG1024 suppresses coronaviral replication by downregulating JAK1 via an IR/IGF-1R independent proteolysis mediated by Ndfip1/2_NEDD4-like E3 ligase itch Pharmaceuticals. 2022 Feb 17;15(2):Article number 241.
    2021-08-13 Remdesivir and cyclosporine synergistically inhibit the human coronaviruses OC43 and SARS-CoV-2 Frontiers in Pharmacology. 2021 Aug 13;12:Article number 706901.
    2020-12-14 Inhibition of SARS-CoV-2 by highly potent broad-spectrum anti-coronaviral tylophorine-based derivatives Frontiers in Pharmacology. 2020 Dec 14;11:Article number 606097.
    2020-12 Natural cardenolides suppress coronaviral replication by downregulating JAK1 via a Na(+)/K(+)-ATPase independent proteolysis[Erratum:Biochemical Pharmacology. 2020 Oct;180:Article number 114122.] Biochemical Pharmacology. 2020 Dec;182:Article number 114287.
    2020-10 Natural cardenolides suppress coronaviral replication by downregulating JAK1 via a Na(+)/K(+)-ATPase independent proteolysis Biochemical Pharmacology. 2020 Oct;180:Article number 114122.
    2020-08-20 Discovery of M protease inhibitors encoded by SARS-CoV-2 Antimicrobial Agents and Chemotherapy. 2020 Aug 20;64(9):e00872-20.
    2020-08 Polyketide synthase gene expression in relation to chloromonilicin and melanin production in Monilinia fructicola Phytopathology. 2020 Aug;110(8):1465-1475.
    2020-08 Artificial intelligence approach fighting COVID-19 with repurposing drugs Biomedical Journal. 2020 Aug;43(4):355-362.
    2020-08 Repurposing old drugs as antiviral agents for coronaviruses Biomedical Journal. 2020 Aug;43(4):368-374.
    2020-02 The cardenolides ouabain and reevesioside A promote FGF2 secretion and subsequent FGFR1 phosphorylation via converged ERK1/2 activation Biochemical Pharmacology. 2020 Feb;172:Article number 113741.
    2020-02 Tylophorine-based compounds are therapeutic in rheumatoid arthritis by targeting the caprin-1 ribonucleoprotein complex and inhibiting expression of associated c-Myc and HIF-1alpha Pharmacological Research. 2020 Feb;152:Article number 104581.
    2019-08-06 Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: An identification of a novel oncotarget[Erratum: Oncotarget. 2015 Feb;6(4):2148-2163.] Oncotarget. 2019 Aug 6;10(47):4919.
    2018-10 The cardenolide ouabain suppresses coronaviral replication via augmenting a Na(+)/K(+)-ATPase-dependent PI3K_PDK1 axis signaling Toxicology and Applied Pharmacology. 2018 Oct;56:90-97.
    2017-10 Identification of anti-viral activity of the cardenolides, Na+/K+-ATPase inhibitors, against porcine transmissible gastroenteritis virus Toxicology and Applied Pharmacology. 2017 Oct;332:129-137.
    2017-07 Design, synthesis, and evaluation of thiazolidine-2,4-dione derivatives as a novel class of glutaminase inhibitors Journal of Medicinal Chemistry. 2017 Jul;60(13):5599-5612.
    2017-06-22 Targeting coronaviral replication and cellular JAK2 mediated dominant NF-kappaB activation for comprehensive and ultimate inhibition of coronaviral activity Scientific Reports. 2017 Jun 22;7:Article number 4105.
    2017-05-22 Bioactive composition of Reevesia formosana root and stem with cytotoxic activity potential RSC Advances. 2017 May 22;7(43):27040-27047.
    2016-10 Cytotoxic cardenolides and sesquiterpenoids from the fruits of Reevesia formosana Phytochemistry. 2016 Oct;130:282-290.
    2016-04 Discovery and development of tylophorine derived dibenzoquinolines-33b compounds into therapeutic agents The FASEB Journal. 2016 Apr;30(1, Suppl.):Meeting Abstract lb56.
    2016-02-22 Guidelines for the use and interpretation of assays for monitoring autophagy [Erratum to: Autophagy. 2016 Jan 2;12(1):1-222.] Autophagy. 2016 Feb 22;12(2):443.
    2016-01-02 Guidelines for the use and interpretation of assays for monitoring autophagy Autophagy. 2016 Jan 2;12(1):1-222.
    2015-07 Biological evaluation of secondary metabolites from the root of machilus obovatifolia Chemistry and Biodiversity. 2015 Jul;12(7):1057-1067.
    2015-04 Tylophorine compounds exert anti-cancer activity by targeting a ribonucleoprotein complex containing caprin-1 and c-Myc mRNA FASEB Journal. 2015 Apr;29(1, Suppl.):Abstract number LB132
    2015-02 Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: An identification of a novel oncotarget Oncotarget. 2015 Feb;6(4):2148-2163.
    2014-11 Chemical constituents and cytotoxic activities from the fruits of Reevesia formosana Planta Medica. 2014 Nov;80(16):1541.
    2014-11 Chemical constituents and cytotoxic activities from the root and the stem of Reevesia formosana Planta Medica. 2014 Nov;80(16):1541.
    2014-08 Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells Oncotarget. 2014 Aug;5(15):6087-6101.
    2014-05-11 二苯並〔f,h〕異喹啉衍生物及其醫藥組成物 I436983/2014-05-11
    2014-03-21 菲并吲哚啶類似物 I430794/2014-03-21
    2014-01 A novel dengue virus inhibitor, BP13944, discovered by high-throughput screening with dengue virus replicon cells selects for resistance in the viral NS2B/NS3 protease Antimicrobial Agents and Chemotherapy. 2014 Jan;58(1):110-119.
    2013-07-16 Dibenzo[f,h]isoquinoline derivatives US8486959B2/2013-07-16
    2013-06 c-Jun-mediated anti-cancer mechanisms of tylophorine Carcinogenesis. 2013 Jun;34(6):1304-1314.
    2013-05-14 Phenanthroindolizidine analogues US8440649B2/2013-05-14
    2013-04-13 Exploration of the role of tylophorine E ring in anti-Coronavirus activity-Tylophorine derived dibenzoquinolines impart multi-biological activities as orally active agents FASEB Journal. 2013 Apr 13;27:lb71.
    2013-04 Tylophorine induces c-Jun protein accumulation through two discrete prolonged pathways NF-kappaB/PKCdelta/JNK and PI3K/PDK1/PP2A/eEF2 to promote G1 arrest in carcinoma cells FASEB Journal. 2013 Apr;27:lb74.
    2013-04 Identification of a quinone compound inhibits human glutaminase activity and induces autophagy in carcinoma cells FASEB Journal. 2013 Apr;27:lb70.
    2013-03 Cytotoxic cardenolide glycosides from the root of Reevesia formosana Phytochemistry. 2013 Mar;87:86-95.
    2012-12-13 Synthesis and biological evaluation of tylophorine-derived dibenzoquinolines as orally active agents: Exploration of the role of tylophorine e ring on biological activity Journal of Medicinal Chemistry. 2012 Dec 13;55(23):10363-10377.
    2011-11 Isolation and biological activities of phenanthroindolizidine and septicine alkaloids from the formosan tylophora ovata Planta Medica. 2011 Nov;77(17):1932-1938.
    2011-01 Novel dengue virus-specific NS2B/NS3 protease inhibitor, BP2109, discovered by a high-throughput screening assay Antimicrobial Agents and Chemotherapy. 2011 Jan;55(1):229-238.
    2011-01 Antitubercular resorcinol analogs and benzenoid C-glucoside from the roots of ardisia cornudentata Planta Medica. 2011 Jan;77(1):60-65.
    2010-11 Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus Antiviral Research. 2010 Nov;88(2):160-168.
    2010-11 Cytotoxic Sesquiterpenes from Magnolia kachirachirai Chemistry and Biodiversity. 2010 Nov;7(11):2737-2747.
    2010-10-11 乙烯磺酸鹽化合物 I331523/2010-10-11
    2010-09 Cytotoxic flavonoids from the leaves of cryptocarya chinensis Journal of Natural Products. 2010 Sep;73(9): 1470-1475.
    2010-04-20 A new butanolide and a new secobutanolide from Litsea lii var. nunkao-tahangensis Natural Product Research. 2010 Apr 20;24(7):647-656.

    顯示項目1-50 / 105. (共3頁)
    1 2 3 > >>
    每頁顯示[10|25|50]項目

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋