國家衛生研究院 NHRI:
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    顯示項目26-50 / 52. (共3頁)
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    日期題名關聯
    2011-01 Novel dengue virus-specific NS2B/NS3 protease inhibitor, BP2109, discovered by a high-throughput screening assay Antimicrobial Agents and Chemotherapy. 2011 Jan;55(1):229-238.
    2011-01 BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities Cancer Science. 2011 Jan;102(1):182-191.
    2010-10 Modulation of microglial immune responses by a novel thiourea derivative Chemico-Biological Interactions. 2010 Oct;188(1):228-236.
    2010-09-01 Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors Bioorganic and Medicinal Chemistry. 2010 Sep ;18(17):6414-6421.
    2010-08-21 硫尿化合物及抑制C型肝炎病毒感染之方法 I329102/2010-08-21
    2010-05-11 咪唑啉酮化合物 I324594/2010-05-11
    2009-11-01 Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors Bioorganic and Medicinal Chemistry Letters. 2009 Nov 1;19(21):6063-6068.
    2009-08-01 Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitors Bioorganic and Medicinal Chemistry Letters. 2009 Aug 1;19(15):4134-4138.
    2009-07 Novel antiviral agent DTriP-22 targets RNA-dependent RNA polymerase of enterovirus 71 Antimicrobial Agents and Chemotherapy. 2009 Jul;53(7):2740-2747.
    2009-04-01 Design, synthesis, and anti-HCV activity of thiourea compounds Bioorganic and Medicinal Chemistry Letters. 2009 Apr 1;19(7):1950-1955.
    2009-03-10 Imidazolidinone compounds US7501445B2/2009-03-10
    2008-10-15 Analogues of 2-phenyl-ethenesulfonic acid phenyl ester have dual functions of inhibiting expression of inducible nitric oxide synthase and activating peroxisome proliferator-activated receptor gamma Bioorganic and Medicinal Chemistry Letters. 2008 Oct 15;18(20):5676-5679.
    2008-05 Antiviral activity of pyridyl imidazolidinones against enterovirus 71 variants Journal of Biomedical Science. 2008 May;15(3):291-300.
    2007-08-21 Imidazolidinone compounds US7259174B2/2007-08-21
    2007-06-01 咪唑啉酮化合物 I281919/2007-06-01
    2006-10-31 Imidazolidinone compounds US7129359B2/2006-10-31
    2006-08-01 抗腸病毒化合物 I259083/2006-08-01
    2005-10-01 Synthesis and antipicornavirus activity of (R)- and (S)-1-[5-(4 '-chlorobiphenyl-4-yloxy)-3-methylpentyl]-3-pyridin-4-yl-imidazolidin-2-one Bioorganic and Medicinal Chemistry Letters. 2005 Oct;15(19):4206-4211.
    2005-05-19 Design, synthesis, and antipicornavirus activity of 1-[5-(4-arylphenoxy)alkyl]-3-pyridin-4-ylimidazolidin-2-one derivatives Journal of Medicinal Chemistry. 2005 May;48(10):3522-3535.
    2004-11-09 Anti-enterovirus compounds US6815444B2/2004-11-09
    2004-10-18 Synthesis and antienteroviral activity of a series of novel, oxime ether-containing pyridyl imidazolidinones Bioorganic and Medicinal Chemistry Letters. 2004 Oct;14(20):5051-5056.
    2004-09 Mutation in enterovirus 71 capsid protein VP1 confers resistance to the inhibitory effects of pyridyl imidazolidinone Antimicrobial Agents and Chemotherapy. 2004 Sep;48(9):3523-3529.
    2004-06-01 咪唑啉酮化合物 203254/2004-06-01
    2004-05-17 Design, synthesis, and structure-activity relationships of pyrazolo[3,4-d]pyrimidinies: a novel class of potent enterovirus inhibitors Bioorganic and Medicinal Chemistry Letters. 2004 May;14(10):2519-2525.
    2004-03-16 Imidazolidinone compounds US6706739B2/2004-03-16

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