| 2022-08 |
Rosmarinic acid interferes with influenza virus A entry and replication by decreasing GSK3beta and phosphorylated AKT expression levels |
Journal of Microbiology, Immunology, and Infection. 2022 Aug;55(4):598-610. |
 |
| 2020-12 |
Rosmarinic acid exhibits broad anti-enterovirus A71 activity by inhibiting the interaction between the five-fold axis of capsid VP1 and cognate sulfated receptors |
Emerging Microbes and Infections. 2020 Dec;9(1):1194-1205. |
|
| 2019-12 |
A novel flavivirus entry inhibitor, BP34610, discovered through high-throughput screening with dengue reporter viruses |
Antiviral Research. 2019 Dec;172:Article number 104636. |
|
| 2019-04-01 |
A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus |
European Journal of Medicinal Chemistry. 2019 Apr 1;167:245-268. |
|
| 2018-09 |
Development of robust genotype 1a hepatitis C replicons harboring adaptive mutations for facilitating the antiviral drug discovery and study of virus replication |
Journal of Virological Methods. 2018 Sep;259:10-17. |
|
| 2017-12 |
Stimulatory actions of a novel thiourea derivative on large-conductance, calcium-activated potassium channels |
Journal of Cellular Physiology. 2017 Dec;232(12):3409-3421. |
|
| 2017-06 |
Mutagenesis of dengue virus protein NS2A revealed a novel domain responsible for virus-induced cytopathic effect and interactions between NS2A and NS2B transmembrane segments |
Journal of Virology. 2017 Jun;91(12):Article number e01836-16. |
|
| 2017-01 |
A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide |
Journal of Medicinal Chemistry. 2017 Jan;60(1):228-247. |
|
| 2016-07 |
In vitro and in vivo studies of a potent capsid-binding inhibitor of enterovirus 71 |
Journal of Antimicrobial Chemotherapy. 2016 Jul;71(7):1922-1932. |
|
| 2014-01 |
A novel dengue virus inhibitor, BP13944, discovered by high-throughput screening with dengue virus replicon cells selects for resistance in the viral NS2B/NS3 protease |
Antimicrobial Agents and Chemotherapy. 2014 Jan;58(1):110-119. |
|
| 2013-02 |
Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems |
Antimicrobial Agents and Chemotherapy. 2013 Feb; 57(2):723-733. |
|
| 2012-01 |
Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor |
Antimicrobial Agents and Chemotherapy. 2012 Jan;56(1):44-53. |
|
| 2011-04 |
Antitumor effect of BPR-DC-2, a novel synthetic cyclic cyanoguanidine derivative, involving the inhibition of MDR-1 expression and down-regulation of p-AKT and PARP-1 in lung cancer |
Investigational New Drugs. 2011 Apr;29(2):195-206. |
|
| 2011-04 |
Isatin-beta-thiosemicarbazones as potent herpes simplex virus inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2011 Apr;21(7):1948-1952. |
|
| 2011-01 |
Novel dengue virus-specific NS2B/NS3 protease inhibitor, BP2109, discovered by a high-throughput screening assay |
Antimicrobial Agents and Chemotherapy. 2011 Jan;55(1):229-238. |
|
| 2011-01 |
BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities |
Cancer Science. 2011 Jan;102(1):182-191. |
|
| 2010-10 |
Modulation of microglial immune responses by a novel thiourea derivative |
Chemico-Biological Interactions. 2010 Oct;188(1):228-236. |
|
| 2010-09-01 |
Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors |
Bioorganic and Medicinal Chemistry. 2010 Sep ;18(17):6414-6421. |
|
| 2009-11-01 |
Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2009 Nov 1;19(21):6063-6068. |
|
| 2009-08-01 |
Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2009 Aug 1;19(15):4134-4138. |
|
| 2009-07 |
Novel antiviral agent DTriP-22 targets RNA-dependent RNA polymerase of enterovirus 71 |
Antimicrobial Agents and Chemotherapy. 2009 Jul;53(7):2740-2747. |
|
| 2009-04-01 |
Design, synthesis, and anti-HCV activity of thiourea compounds |
Bioorganic and Medicinal Chemistry Letters. 2009 Apr 1;19(7):1950-1955. |
|
| 2008-10-15 |
Analogues of 2-phenyl-ethenesulfonic acid phenyl ester have dual functions of inhibiting expression of inducible nitric oxide synthase and activating peroxisome proliferator-activated receptor gamma |
Bioorganic and Medicinal Chemistry Letters. 2008 Oct 15;18(20):5676-5679. |
|
| 2008-05 |
Antiviral activity of pyridyl imidazolidinones against enterovirus 71 variants |
Journal of Biomedical Science. 2008 May;15(3):291-300. |
|
| 2005-10-01 |
Synthesis and antipicornavirus activity of (R)- and (S)-1-[5-(4 '-chlorobiphenyl-4-yloxy)-3-methylpentyl]-3-pyridin-4-yl-imidazolidin-2-one |
Bioorganic and Medicinal Chemistry Letters. 2005 Oct;15(19):4206-4211. |
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