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Rosmarinic acid interferes with inf...
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Development of robust genotype 1a h...
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A potent, selective, and orally bio...
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2022-08
Rosmarinic acid interferes with influenza virus A entry and replication by decreasing GSK3beta and phosphorylated AKT expression levels
Journal of Microbiology, Immunology, and Infection. 2022 Aug;55(4):598-610.
2020-12
Rosmarinic acid exhibits broad anti-enterovirus A71 activity by inhibiting the interaction between the five-fold axis of capsid VP1 and cognate sulfated receptors
Emerging Microbes and Infections. 2020 Dec;9(1):1194-1205.
2019-12
A novel flavivirus entry inhibitor, BP34610, discovered through high-throughput screening with dengue reporter viruses
Antiviral Research. 2019 Dec;172:Article number 104636.
2019-04-01
A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus
European Journal of Medicinal Chemistry. 2019 Apr 1;167:245-268.
2018-09
Development of robust genotype 1a hepatitis C replicons harboring adaptive mutations for facilitating the antiviral drug discovery and study of virus replication
Journal of Virological Methods. 2018 Sep;259:10-17.
2017-12
Stimulatory actions of a novel thiourea derivative on large-conductance, calcium-activated potassium channels
Journal of Cellular Physiology. 2017 Dec;232(12):3409-3421.
2017-06
Mutagenesis of dengue virus protein NS2A revealed a novel domain responsible for virus-induced cytopathic effect and interactions between NS2A and NS2B transmembrane segments
Journal of Virology. 2017 Jun;91(12):Article number e01836-16.
2017-01
A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide
Journal of Medicinal Chemistry. 2017 Jan;60(1):228-247.
2016-07
In vitro and in vivo studies of a potent capsid-binding inhibitor of enterovirus 71
Journal of Antimicrobial Chemotherapy. 2016 Jul;71(7):1922-1932.
2015-07-29
脯氨酸衍生物
ZL201080002506.6/2015-07-29
2015-05-29
Proline derivatives
JP5753185/2015-05-29
2014-09-01
治療阿茲海默症或帕金森氏症之醫藥組成物
I450716/2014-09-01
2014-03-11
脯胺酸衍生物
I429645/2014-03-11
2014-01
A novel dengue virus inhibitor, BP13944, discovered by high-throughput screening with dengue virus replicon cells selects for resistance in the viral NS2B/NS3 protease
Antimicrobial Agents and Chemotherapy. 2014 Jan;58(1):110-119.
2013-04-09
Proline derivatives
US8415482B2/2013-04-09
2013-02
Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems
Antimicrobial Agents and Chemotherapy. 2013 Feb; 57(2):723-733.
2012-06-12
Treatment of neurodegenerative disorders with thiourea compounds
US8198284B2/2012-06-12
2012-04-11
咪唑啉酮及咪唑啉硫酮衍生物
I361808/2012-04-11
2012-03-01
C型肝炎病毒抑制劑
I359137/2012-03-01
2012-01
Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor
Antimicrobial Agents and Chemotherapy. 2012 Jan;56(1):44-53.
2011-07-26
Hepatitis C virus inhibitors
US7985763B2/2011-07-26
2011-05-10
Imidazolidinone and imidazolidinethione derivatives
US7939523B2/2011-05-10
2011-04
Antitumor effect of BPR-DC-2, a novel synthetic cyclic cyanoguanidine derivative, involving the inhibition of MDR-1 expression and down-regulation of p-AKT and PARP-1 in lung cancer
Investigational New Drugs. 2011 Apr;29(2):195-206.
2011-04
Isatin-beta-thiosemicarbazones as potent herpes simplex virus inhibitors
Bioorganic and Medicinal Chemistry Letters. 2011 Apr;21(7):1948-1952.
2011-03-01
Thiourea derivatives
US7897764B2/2011-03-01
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