國家衛生研究院 NHRI:
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    近3年内发表的文件:19(12.10%)
    含全文笔数:157(100.00%)

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    最后更新时间: 2024-12-01 14:05


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    日期题名關聯
    2019-03 Mutagenesis of the dengue virus NS4A protein reveals a novel cytosolic N-terminal domain responsible for virus-induced cytopathic effects and intramolecular interactions within the N-terminus of NS4A Journal of General Virology. 2019 Mar;100(3):457-470.
    2019-01 CSC-3436 inhibits TWIST-induced epithelial-mesenchymal transition via the suppression of Twist/Bmi1/Akt pathway in head and neck squamous cell carcinoma Journal of Cellular Physiology. 2019 Jan;234(6):9118-9129.
    2019-01 CCM111 prevents hepatic fibrosis via cooperative inhibition of TGF-Beta Wnt and STAT3 signaling pathways Journal of Food and Drug Analysis. 2019 Jan;27(1):184-194.
    2018-08-24 BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor Cancer Science. 2018 Nov;109(11):3591-3601.
    2018-07 An intestinal "Transformers"-like nanocarrier system for enhancing the oral bioavailability of poorly water-soluble drugs ACS Nano. 2018 Jul;12(7):6389-6397.
    2018-04 Effects of female sex hormones on folic acid-induced anti-angiogenesis Acta Physiologica. 2018 Apr;222:Article number e13001.
    2018-04 PSPC1 mediates TGF-beta1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis Nature Cell Biology. 2018 Apr;20(4):479-491.
    2018-02-08 Development of stem-cell-mobilizing agents targeting CXCR4 receptor for peripheral blood stem cell transplantation and beyond Journal of Medicinal Chemistry. 2018 Feb 8;61(3):818-833.
    2018-01-01 Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2 European Journal of Medicinal Chemistry. 2018 Jan 1;143:611-620.
    2017-12 Enhanced B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II poison-resistant cancer cells Free Radical Biology and Medicine. 2017 Dec;113:505-518.
    2017-07-07 CCM111, the water extract of Antrodia cinnamomea, regulates immune-related activity through STAT3 and NF-kappaB pathways Scientific Reports. 2017 Jul 07;7(1):Article number 4862.
    2017-07 Design, synthesis, and evaluation of thiazolidine-2,4-dione derivatives as a novel class of glutaminase inhibitors Journal of Medicinal Chemistry. 2017 Jul;60(13):5599-5612.
    2017-07 Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates Bioconjugate Chemistry. 2017 Jul;28(7):1878-1892.
    2017-05 1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: A novel opioid receptor agonist with less accompanying gastrointestinal dysfunction than morphine Anesthesiology. 2017 May;126(5):952-966.
    2017-04 A novel CXCR4 antagonist CX549 induces neuroprotection in stroke brain Cell Transplantation. 2017 Apr;26(4):571-583.
    2016-12 Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation Oncotarget. 2016 Dec;7(52):86239-86256.
    2016-10 BPR1J373, an oral multiple tyrosine kinase inhibitor, targets c-KIT for the treatment of c-KIT driven myeloid leukemia Molecular Cancer Therapeutics. 2016 Oct;15(10):2323-2333.
    2016-05 N-Indolylglycosides bearing modifications at the glucose C6-Position as Sodium-Dependent Glucose Co-transporter 2 inhibitors Bioorganic and Medicinal Chemistry. 2016 May;24(10):2242-2250.
    2015-09 Self-assembling bubble carriers for oral protein delivery Biomaterials. 2015 Sep;64:115-124.
    2015-08 Novel Nrf2/ARE activator, trans-coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38alpha/MAPKAPK-2 and PK-N3 signaling pathway Chemical Research in Toxicology. 2015 Aug ;28(9):1681-1692.
    2015-07 Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations European Journal of Medicinal Chemistry. 2015 Jul;100:151-161.
    2015-04 IL-1beta promotes malignant transformation and tumor aggressiveness in oral cancer Journal of Cellular Physiology. 2015 APR;230(4):875-884.
    2015-03 Stem cell mobilizers targeting chemokine receptor CXCR4: Renoprotective application in acute kidney injury Journal of Medicinal Chemistry. 2015 Mar;58(5):2315-2325.
    2014-08-04 Effects of dipeptidyl peptidase-4 inhibition with MK-0431 on syngeneic mouse islet transplantation International Journal of Endocrinology. 2014 Aug 4;2014:Article ID 795283.
    2014-04 Treatment of chemotherapy-induced neutropenia in a rat model by using multiple daily doses of oral administration of G-CSF-containing nanoparticles Biomaterials. 2014 Apr;35(11):3641-3649.

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