國家衛生研究院 NHRI:
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    近3年内发表的文件:13(5.63%)
    含全文笔数:171(74.03%)

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    显示项目151-175 / 231. (共10页)
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    日期题名關聯
    2009-07-23 Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4221-4233.
    2009-07-03 Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers Molecular Cancer. 2009 Jul 3;8:Article number 43.
    2009-06-09 Treatment of coronavirus infection US7544712B1/2009-06-09
    2009-05-05 Indole compounds US7528165B2/2009-05-05
    2009-05 Down-regulation of survivin enhances sensitivity to BPROL075 in human cancer cells via caspase-independent mechanisms Cancer Research. 2009 May;69:Abstract number 5542.
    2009-04-24 Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway Journal of Biological Chemistry. 2009 Apr 24;284(17):11121-11133.
    2009-04-23 Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists Journal of Medicinal Chemistry. 2009 Apr 23;52(8):2618-2622.
    2009-04-17 Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents ChemMedChem. 2009 Apr 17;4(4):588-593.
    2009-04 Aurora kinase inhibitors in preclinical and clinical testing Expert Opinion on Investigational Drugs. 2009 Apr;18(4):379-398.
    2009-03 Advances in Aurora kinase inhibitor patents Expert Opinion on Therapeutic Patents. 2009 Mar;19(3):321-356.
    2009-03 Discovery and development of novel furano-pyrimidine analogs as Aurora kinase inhibitors Abstracts of Papers - American Chemical Society. 2009 Mar;237:MEDI 221.
    2009-02-26 Structure-based drug design of novel aurora kinase a inhibitors: Structural basis for potency and specificity Journal of Medicinal Chemistry. 2009 Feb 26;52(4):1050-1062.
    2009-02 Aurintricarboxylic acid inhibits influenza virus neuraminidase Antiviral Research. 2009 Feb;81(2):123-131.
    2009-01-22 Pyrrolidine compounds AU2005221678/2009-01-22
    2008-12-25 Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents Journal of Medicinal Chemistry. 2008 Dec 25;51(24):8163-8167.
    2008-12-11 吲哚化合物 I304066/2008-12-11
    2008-11-25 Anti-tumor compounds US7456289B2/2008-11-25
    2008-11-11 Indole compounds US7449478B2/2008-11-11
    2008-09-16 Pyrrolidine compounds US7425633B2/2008-09-16
    2008-07-24 Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors Journal of Medicinal Chemistry. 2008 Jul;51(14):4351-4355.
    2008-07-21 吡咯啉啶化合物 I299039/2008-07-21
    2008-07-01 Pyrrolidine compounds KR10-0844593/2008-07-01
    2008-07 Anti-HSV activity of digitoxin and its possible mechanisms Antiviral Research. 2008 Jul;79(1):62-70.
    2008-06-01 A cell-based high-throughput screen for epidermal growth factor receptor pathway inhibitors Analytical Biochemistry. 2008 Jun;377(1):89-94.
    2008-05-01 抗腫瘤化合物 I296195/2008-05-01

    显示项目151-175 / 231. (共10页)
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