國家衛生研究院 NHRI:
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    Last Update: 2024-11-28 14:48


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    Showing items 1-25 of 73. (3 Page(s) Totally)
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    DateTitleRelation
    2023-03-17 A convenient diels-alder approach toward potential polyketide-like antibiotics using alpha-activated alpha,Beta-unsaturated 4,4-dimethyl-1-tetralones as dienophiles Molecules. 2023 Mar 17;28(6):Article number 2739.
    2023-01 Modulating the affinity and signaling bias of cannabinoid receptor 1 antagonists Bioorganic Chemistry. 2023 Jan;130:Article number 106236.
    2022-10-03 Protective effect of CXCR4 antagonist DBPR807 against ischemia-reperfusion injury in a rat and porcine model of myocardial infarction: Potential adjunctive therapy for percutaneous coronary intervention International Journal of Molecular Sciences. 2022 Oct 3;23(19):Article number 11730.
    2022-03-02 Discovery of potential neuroprotective agents against paclitaxel-induced peripheral neuropathy Journal of Medicinal Chemistry. 2022 Mar 2;65(6):4767-4782.
    2021-07-21 Anionic diels-alder chemistry of cyclic sodium dien-1-olates delivering highly stereoselective and functionalized polycyclic adducts Organic Letters. 2021 Jul 21;23(15):5709-5713.
    2021-03-30 A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment Proceedings of the National Academy of Sciences of the United States of America. 2021 Mar 30;118(13):Article number e2015433118.
    2021-03-02 Total synthesis of landomycins Q and R and related core structures for exploration of the cytotoxicity and antibacterial properties RSC Advances. 2021 Mar 2;11(16):9426-9432.
    2020-09-25 Protective effect of CXCR4 antagonist CX807 in a rat model of hemorrhagic stroke International Journal of Molecular Sciences. 2020 Sep 25;21(19):Article number 7085.
    2020-04 Development of a cross-conjugated vinylogous [4+2] anionic annulation and application to the total synthesis of natural antibiotic (±)-ABX Angewandte Chemie. 2020 Apr;59(16):6540-6545.
    2020-02-10 Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors Journal of Medicinal Chemistry. 2020 Feb 10;63(4):1642-1659.
    2020-01-16 Development of a cross-conjugated vinylogous [4+2] anionic annulation and application to the total synthesis of natural antibiotic (±)-ABX Advanced Materials. 2020 Jan 16;132(16):6602-6607.
    2020-01-06 Biosynthetic engineering of the antifungal, anti-MRSA auroramycin Microbial Cell Factories. 2020 Jan 6;19:Article number 3.
    2019-07-11 Linker optimization and therapeutic evaluation of phosphatidylserine-targeting zinc dipicolylamine-based drug conjugates Journal of Medicinal Chemistry. 2019 Jul 11;62(13):6047-6062.
    2019-05 Characterization, dynamics, and mechanism of CXCR4 antagonists on a constitutively active mutant Cell Chemical Biology. 2019 May;26(5):662-673.e7.
    2019-01-01 Fluorine-18 isotope labeling for positron emission tomography imaging. Direct evidence for DBPR211 as a peripherally restricted CB1 inverse agonist Bioorganic and Medicinal Chemistry. 2019 Jan 1;27(1):216-223.
    2018-12-07 Temperature-controlled thiation of alpha-Cyano-beta-Alkynyl carbonyl derivatives for de vovo synthesis of 2-Aminothiophenes and thieno[2,3- c]isothiazoles Journal of Organic Chemistry. 2018 Dec 7;83(23):14688-14697.
    2018-08 Auroramycin: A potent antibiotic from streptomyces roseosporus by CRISPR-Cas9 activation Chembiochem: A European Journal of Chemical Biology. 2018 Aug;19(16):1716-1719.
    2018-07 Harnessing CXCR4 antagonists in stem cell mobilization, HIV infection, ischemic diseases, and oncology Medicinal Research Reviews. 2018 Jul;38(4):1188-1234.
    2018-07 Synergic effect of curcumin and its structural analogue (Monoacetylcurcumin) on anti-influenza virus infection Journal of Food and Drug Analysis. 2018 Jul;26(3):1015-1023.
    2018-05-22 Total synthesis of tetarimycin A, (±)-Naphthacemycin A9, and (±)-Fasamycin A: structure-activity relationship studies against drug-resistant bacteria Journal of Organic Chemistry. 2018 May 22;83(12):6508-6523.
    2018-02-08 Development of stem-cell-mobilizing agents targeting CXCR4 receptor for peripheral blood stem cell transplantation and beyond Journal of Medicinal Chemistry. 2018 Feb 8;61(3):818-833.
    2017-07 Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates Bioconjugate Chemistry. 2017 Jul;28(7):1878-1892.
    2017-04 A novel CXCR4 antagonist CX549 induces neuroprotection in stroke brain Cell Transplantation. 2017 Apr;26(4):571-583.
    2016-12-08 Bromomethylthioindole inspired carbazole hybrids as promising class of anti-MRSA agents ACS Medicinal Chemistry Letters. 2016 Dec 8;7(12):1191-1196.
    2016-11-18 Cobalt(II)-catalyzed aerobic oxidation of terminal-capped alkynyl alpha-cyano alkanone systems. An oxygen-mediated radical chain reaction Journal of Organic Chemistry. 2016 Nov 18;81(22):10759-10768.

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