國家衛生研究院 NHRI:
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    近3年内发表的文件:19(8.96%)
    含全文笔数:180(84.91%)

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    日期题名關聯
    2012-02 Discovery of novel stem cell mobilizers that target the CXCR4 receptor ChemMedChem. 2012 Feb;7(2):209-212.
    2012-01 BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML British Journal of Cancer. 2012 Jan;106(3):475-481.
    2011-11 Effects of chitosan-nanoparticle-mediated tight junction opening on the oral absorption of endotoxins Biomaterials. 2011 Nov;32(33):8712-8721.
    2011-10 Antiproliferative effects of N-heterocyclic indolyl glyoxylamide derivatives on human lung cancer cells Anticancer Research. 2011 Oct;31(10):3407-3415.
    2011-09-27 Formulations of indol-3-yl-2-oxoacetamide compounds US8026271B2/2011-09-27
    2011-09 Effects of dipeptidyl peptidase 4 inhibition with MK-0431 on syngeneic mouse islet transplantation Diabetologia. 2011 Sep;54(Suppl. 1):S181.
    2011-07 Immune response and pathophysiological features of Klebsiella pneumoniae liver abscesses in an animal model Laboratory Investigation. 2011 Jul;91(7):1029-1039.
    2011-07 Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) Bioorganic and Medicinal Chemistry. 2011 Jul;19(14):4173-4182 .
    2011-05 Quercetin and rutin reduced the bioavailability of cyclosporine from Neoral, an immunosuppressant, through activating P-glycoprotein and CYP 3A4 Journal of Agricultural and Food Chemistry. 2011 May;59(9):4644-4648.
    2011-05 Study of glioblastoma multiforme metastatic and invasive mechanism by polycistronic imaging probe in tumor implanted animal model Journal of Nuclear Medicine. 2011 May;52(Suppl. 1):Meeting Abstract 1709.
    2011-03-27 Design and synthesis of potent Aurora kinase inhibitors Abstracts of Papers - American Chemical Society. 2011 Mar 27;241:258-MEDI.
    2011-01-13 Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes Journal of Medicinal Chemistry. 2011 Jan 13;54(1):166-178.
    2011-01 BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities Cancer Science. 2011 Jan;102(1):182-191.
    2010-12 Discovery of non-glycoside sodium-dependent glucose Co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening Journal of Medicinal Chemistry. 2010 Dec;53(24):8770-8774.
    2010-11 Self-assembled pH-sensitive nanoparticles: A platform for oral delivery of protein drugs Advanced Functional Materials. 2010 Nov;20(21):3695-3700.
    2010-11 Do neutrophils play a role in establishing liver abscesses and distant metastases caused by Klebsiella pneumoniae? PLoS ONE. 2010 Nov;5(11):Article number e15005.
    2010-10-28 Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency Journal of Medicinal Chemistry. 2010 Oct 28;53(20):7316-7326.
    2010-09 Intravenous paclitaxel against metastasis of human gastric tumors of diffuse type Cancer Chemotherapy and Pharmacology. 2010 Sep;66(4):773-783.
    2010-08 Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models Abstracts of Papers - American Chemical Society. 2010 Aug;240:MEDI 332.
    2010-07 Antiangiogenic Activities and Cisplatin-combined Antitumor Activities of BPR0L075 Anticancer Research. 2010 Jul;30(7):2813-2822.
    2010-06-15 (2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV Bioorganic and Medicinal Chemistry Letters. 2010 Jun 15;20(12):3596-3600.
    2010-05-11 咪唑胺化合物 I324596/2010-05-11
    2010-05-11 咪唑啉酮化合物 I324594/2010-05-11
    2010-04-21 吲哚-3-基-2-氧乙醯胺衍生物之新化合物及其醫藥組合物與製備方法 I323658/2010-04-21
    2010-03 Sex differences in high-fat diet-induced obesity, metabolic alterations and learning, and synaptic plasticity deficits in mice Obesity. 2010 Mar;18(3):463-469.

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