本發明與一種含有雜原子的新化合物與其組合物以及他們的預防與治療疾病之方法有關。本發明亦提供了如何製造這些化合物的方法。本發明是基於發現一些含有雜原子的化合物，即3-氧乙醯胺吲哚基(3-oxoacetamideindolyl)化合物，具有潛在的抗癌、細胞毒性與抗血管增生的活性。 This invention relates to novel heteroatom containing compounds and compositions thereof, and their use for the prevention and treatment of disease. The invention also provides for methods of making the compounds. The invention is based on the discovery that certain heteroatom containing compounds, 3-oxoacetamideindolyl compounds, have potent anticancer, cytotoxic, and anti-angiogenic activity.
