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显示项目101-125 / 152. (共7页) << < 1 2 3 4 5 6 7 > >> 每页显示[10|25|50]项目

日期	题名	關聯
2013-01	3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor	ChemMedChem. 2013 Jan;8(1):136-148.
2012-12-13	Synthesis and biological evaluation of tylophorine-derived dibenzoquinolines as orally active agents: Exploration of the role of tylophorine e ring on biological activity	Journal of Medicinal Chemistry. 2012 Dec 13;55(23):10363-10377.
2012-11	BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia	European Journal of Cancer. 2012 Nov;48(Suppl. 6):53-54.
2012-09	Synthesis and biological evaluation of novel C-indolylxylosides as sodium-dependent glucose co-transporter 2 inhibitors	European Journal of Medicinal Chemistry. 2012 Sep;55:32-38.
2012-09	Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization	ChemMedChem. 2012 Sep;7(9):1546-1550.
2012-06-07	3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	Bioorganic and Medicinal Chemistry Letters. 2012 Jun 7;22(14):4654-4659.
2012-06	Effects of Bu-Zhong-Yi-Qi-Tang on hepatic drug-metabolizing enzymes and plasma tolbutamide concentration in rats	Journal of Ethnopharmacology. 2012 Jun;142(1):121-128.
2012-04	Synthesis and biological evaluation of 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indoles as potent histone deacetylase inhibitors with antitumor activity in vivo	Journal of Medicinal Chemistry. 2012 Apr;55(8):3777-3791.
2012-02-01	Kinetics and tissue distribution of neutron-activated zinc oxide nanoparticles and zinc nitrate in mice: Effects of size and particulate nature	Nanotechnology. 2012 Feb 1;23(8):Article number 085102.
2012-01	Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor	Antimicrobial Agents and Chemotherapy. 2012 Jan;56(1):44-53.
2012-01	BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML	British Journal of Cancer. 2012 Jan;106(3):475-481.
2011-09-27	Formulations of indol-3-yl-2-oxoacetamide compounds	US8026271B2/2011-09-27
2011-08	BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells	PLoS ONE. 2011 Aug;6(8):Article number e23485.
2011-07	Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	Bioorganic and Medicinal Chemistry. 2011 Jul;19(14):4173-4182 .
2011-04-28	Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents	Journal of Medicinal Chemistry. 2011 Apr 28;54(8):3076-3080.
2011-03-27	Design and synthesis of potent Aurora kinase inhibitors	Abstracts of Papers - American Chemical Society. 2011 Mar 27;241:258-MEDI.
2011-03	Comparative tissue distributions of cadmium chloride and cadmium-based quantum dot 705 in mice: Safety implications and applications	Nanotoxicology. 2011 Mar;5(1):91-97.
2011-03	Effect of shengmai san on insulin resistance, tumor necrosis factor-alpha and oxidative stress in rats fed on a high-fat diet	Journal of Food and Drug Analysis. 2011 Mar;19(1):40-48.
2011-03	Potent EGFR tyrosine kinase inhibitors as anticancer agents	Abstracts of Papers - American Chemical Society. 2011 Mar;241:257-MEDI.
2011-01-13	Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes	Journal of Medicinal Chemistry. 2011 Jan 13;54(1):166-178.
2011-01	BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities	Cancer Science. 2011 Jan;102(1):182-191.
2010-11	Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus	Antiviral Research. 2010 Nov;88(2):160-168.
2010-10-28	Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency	Journal of Medicinal Chemistry. 2010 Oct 28;53(20):7316-7326.
2010-10	Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities	Pharmacological Research. 2010 Oct;62(4):337-343.
2010-09-01	Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors	Bioorganic and Medicinal Chemistry. 2010 Sep ;18(17):6414-6421.

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