國家衛生研究院 NHRI:
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    Patents [0/8]
    Periodical Articles [119/120]
    Conference Papers/Meeting Abstract [14/24]

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    Showing items 101-125 of 152. (7 Page(s) Totally)
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    DateTitleRelation
    2013-01 3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor ChemMedChem. 2013 Jan;8(1):136-148.
    2012-12-13 Synthesis and biological evaluation of tylophorine-derived dibenzoquinolines as orally active agents: Exploration of the role of tylophorine e ring on biological activity Journal of Medicinal Chemistry. 2012 Dec 13;55(23):10363-10377.
    2012-11 BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia European Journal of Cancer. 2012 Nov;48(Suppl. 6):53-54.
    2012-09 Synthesis and biological evaluation of novel C-indolylxylosides as sodium-dependent glucose co-transporter 2 inhibitors European Journal of Medicinal Chemistry. 2012 Sep;55:32-38.
    2012-09 Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization ChemMedChem. 2012 Sep;7(9):1546-1550.
    2012-06-07 3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) Bioorganic and Medicinal Chemistry Letters. 2012 Jun 7;22(14):4654-4659.
    2012-06 Effects of Bu-Zhong-Yi-Qi-Tang on hepatic drug-metabolizing enzymes and plasma tolbutamide concentration in rats Journal of Ethnopharmacology. 2012 Jun;142(1):121-128.
    2012-04 Synthesis and biological evaluation of 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indoles as potent histone deacetylase inhibitors with antitumor activity in vivo Journal of Medicinal Chemistry. 2012 Apr;55(8):3777-3791.
    2012-02-01 Kinetics and tissue distribution of neutron-activated zinc oxide nanoparticles and zinc nitrate in mice: Effects of size and particulate nature Nanotechnology. 2012 Feb 1;23(8):Article number 085102.
    2012-01 Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor Antimicrobial Agents and Chemotherapy. 2012 Jan;56(1):44-53.
    2012-01 BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML British Journal of Cancer. 2012 Jan;106(3):475-481.
    2011-09-27 Formulations of indol-3-yl-2-oxoacetamide compounds US8026271B2/2011-09-27
    2011-08 BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells PLoS ONE. 2011 Aug;6(8):Article number e23485.
    2011-07 Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) Bioorganic and Medicinal Chemistry. 2011 Jul;19(14):4173-4182 .
    2011-04-28 Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents Journal of Medicinal Chemistry. 2011 Apr 28;54(8):3076-3080.
    2011-03-27 Design and synthesis of potent Aurora kinase inhibitors Abstracts of Papers - American Chemical Society. 2011 Mar 27;241:258-MEDI.
    2011-03 Comparative tissue distributions of cadmium chloride and cadmium-based quantum dot 705 in mice: Safety implications and applications Nanotoxicology. 2011 Mar;5(1):91-97.
    2011-03 Effect of shengmai san on insulin resistance, tumor necrosis factor-alpha and oxidative stress in rats fed on a high-fat diet Journal of Food and Drug Analysis. 2011 Mar;19(1):40-48.
    2011-03 Potent EGFR tyrosine kinase inhibitors as anticancer agents Abstracts of Papers - American Chemical Society. 2011 Mar;241:257-MEDI.
    2011-01-13 Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes Journal of Medicinal Chemistry. 2011 Jan 13;54(1):166-178.
    2011-01 BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities Cancer Science. 2011 Jan;102(1):182-191.
    2010-11 Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus Antiviral Research. 2010 Nov;88(2):160-168.
    2010-10-28 Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency Journal of Medicinal Chemistry. 2010 Oct 28;53(20):7316-7326.
    2010-10 Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities Pharmacological Research. 2010 Oct;62(4):337-343.
    2010-09-01 Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors Bioorganic and Medicinal Chemistry. 2010 Sep ;18(17):6414-6421.

    Showing items 101-125 of 152. (7 Page(s) Totally)
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