| 2010-09 |
Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophe n-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist |
ChemMedChem. 2010 Sep;5(9):1439-1443. |
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| 2010-08 |
Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein |
Journal of Medicinal Chemistry. 2010 Aug;53(18):6572-6583. |
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| 2010-07 |
Antiangiogenic Activities and Cisplatin-combined Antitumor Activities of BPR0L075 |
Anticancer Research. 2010 Jul;30(7):2813-2822. |
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| 2010-06-15 |
(2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV |
Bioorganic and Medicinal Chemistry Letters. 2010 Jun 15;20(12):3596-3600. |
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| 2010-02 |
Antitumor activities and pharmacokinetics of silatecans DB-67 and DB-91 |
Pharmacological Research. 2010 Feb;61(2):108-115. |
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| 2009-08-13 |
Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach |
Journal of Medicinal Chemistry. 2009 Aug 13;52(15):4941-4945. |
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| 2009-07-23 |
Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice |
Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4496-4510. |
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| 2009-07-15 |
Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor |
Biochemical Pharmacology. 2009 Jul 15;78(2):203-210. |
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| 2009-07 |
Effect of taurine supplementation on cytochrome P450 2E1 and oxidative stress in the liver and kidneys of rats with streptozotocin-induced diabetes |
Food and Chemical Toxicology. 2009 Jul;47(7):1703-1709. |
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| 2009-04-17 |
Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents |
ChemMedChem. 2009 Apr 17;4(4):588-593. |
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| 2009-04-01 |
Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2009 Apr 1;19(7):1908-1912. |
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| 2009-03-15 |
Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors |
Bioorganic and Medicinal Chemistry. 2009 Mar 15;17(6):2388-2399. |
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| 2009-02 |
Involvement of oxidative stress and activation of aryl hydrocarbon receptor in elevation of CYP1A1 expression and activity in lung cells and tissues by arsenic: An in vitro and in vivo study |
Toxicological Sciences. 2009 Feb;107(2):385-393. |
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| 2008-07-09 |
Enhanced oral bioavailability of paclitaxel by D-alpha-tocopheryl polyethylene glycol 400 succinate in mice |
International Journal of Pharmaceutics. 2008 Jul;359(1-2):174-181. |
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| 2008-07 |
Computational and ultrastructural toxicology of a nanoparticle, Quantum Dot 705, in mice |
Environmental Science and Technology. 2008 Jul;42(16):6264-6270. |
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| 2008-05 |
High-performance liquid chromatography-electrospray mass spectrometry for the simultaneous determination of multiple active components in Sheng-Mai San, a prescription of traditional Chinese medicine |
Phytochemical Analysis. 2008 May-Jun;19(3):258-265. |
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| 2008-02-28 |
Shengmai San reduces hepatic lipids and lipid peroxidation in rats fed on a high-cholesterol diet |
Journal of Ethnopharmacology. 2008 Feb;116(1):49-57. |
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| 2008-02 |
The inhibitory effect of tannic acid on cytochrome P450 enzymes and NADPH-CYP reductase in rat and human liver microsomes |
Food and Chemical Toxicology. 2008 Feb;46(2):645-653. |
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| 2007-10-01 |
Rapid and sensitive determination of fentanyl in dog plasma by on-line solid-phase extraction integrated with a hydrophilic column coupled to tandem mass spectrometry |
Journal of Chromatography B. 2007 Oct;857(2):195-201. |
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| 2007-10 |
Differential effects of arsenic on cyp1 enzymes in vitro and in vivo |
Drug Metabolism Reviews. 2007 Oct;39(Suppl. 1):209. |
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| 2007-09-15 |
Quantitative determination of salidroside in rat plasma by on-line solid-phase extraction integrated with high-performance liquid chromatography/electrospray ionization tandem mass spectrometry |
Journal of Chromatography B. 2007 Sep;857(1):164-169. |
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| 2007-09 |
Persistent tissue kinetics and redistribution of nanoparticles, quantum dot 705, in mice: ICP-MS quantitative assessment |
Environmental Health Perspectives. 2007 Sep;115(9):1339-1343. |
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| 2007-07 |
Biotransformation of 6-methoxy-3-(3 ',4 ',5 '-trimethoxy-benzoyl)-1-hindole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes |
Drug Metabolism and Disposition. 2007 Jul;35(7):1042-1049. |
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| 2007-02-01 |
Development and validation of a liquid chromatography-tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: Application to a pharmacokinetic study |
Journal of Chromatography B. 2007 Feb;846(1-2):162-168. |
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| 2006-12 |
Pharmacokinetics of anti-SARS-CoV agent niclosamide and its analogs in rats |
Journal of Food and Drug Analysis. 2006 Dec;14(4):329-333. |
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