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生技與藥物研究所
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專利
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期刊論文
[
119
/120]
會議論文/會議摘要
[
14
/24]
Siblings
伍素瑩
[
52
/65]
其他
[
58
/60]
夏克山
[
76
/98]
岳嶽
[
29
/32]
張仲明
[
7
/9]
張俊彥
[
18
/18]
張竣評
[
21
/26]
徐祖安
[
170
/215]
李秀珠
[
75
/105]
李靜琪
[
23
/24]
林書玉
[
19
/20]
洪明秀
[
31
/40]
潘秀玲(2009-2013)
[
16
/17]
王文傑
[
13
/15]
王鴻俊
[
7
/7]
石全(2014-2017)
[
35
/39]
童俊維
[
23
/23]
紀雅惠
[
21
/25]
翁紹華
[
22
/24]
莊宏
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1
/1]
葉修華
[
24
/25]
蔣維棠
[
41
/66]
謝興邦
[
171
/231]
趙宇生(2002-2013)
[
120
/212]
郭靜娟
[
49
/55]
鄒倫
[
28
/29]
陳志豪
[
31
/52]
陳新(2002-2015)
[
53
/67]
陳炯東
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180
/212]
顏婉菁
[
6
/7]
許明珠(1997-2001)
[
3
/10]
陳淑貞(1998-2001)
[
3
/11]
陳華鍵(1997-2001)
[
9
/9]
Community Statistics
近3年內發表的文件:19(12.50%)
含全文筆數:133(87.50%)
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最後更新時間: 2024-12-01 01:43
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DBPR116, a prodrug of BPRMU191, in ...
Discovery of a mu-opioid receptor m...
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Showing items 101-125 of 152. (7 Page(s) Totally)
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Date
Title
Relation
2013-01
3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor
ChemMedChem. 2013 Jan;8(1):136-148.
2012-12-13
Synthesis and biological evaluation of tylophorine-derived dibenzoquinolines as orally active agents: Exploration of the role of tylophorine e ring on biological activity
Journal of Medicinal Chemistry. 2012 Dec 13;55(23):10363-10377.
2012-11
BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia
European Journal of Cancer. 2012 Nov;48(Suppl. 6):53-54.
2012-09
Synthesis and biological evaluation of novel C-indolylxylosides as sodium-dependent glucose co-transporter 2 inhibitors
European Journal of Medicinal Chemistry. 2012 Sep;55:32-38.
2012-09
Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization
ChemMedChem. 2012 Sep;7(9):1546-1550.
2012-06-07
3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)
Bioorganic and Medicinal Chemistry Letters. 2012 Jun 7;22(14):4654-4659.
2012-06
Effects of Bu-Zhong-Yi-Qi-Tang on hepatic drug-metabolizing enzymes and plasma tolbutamide concentration in rats
Journal of Ethnopharmacology. 2012 Jun;142(1):121-128.
2012-04
Synthesis and biological evaluation of 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indoles as potent histone deacetylase inhibitors with antitumor activity in vivo
Journal of Medicinal Chemistry. 2012 Apr;55(8):3777-3791.
2012-02-01
Kinetics and tissue distribution of neutron-activated zinc oxide nanoparticles and zinc nitrate in mice: Effects of size and particulate nature
Nanotechnology. 2012 Feb 1;23(8):Article number 085102.
2012-01
Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor
Antimicrobial Agents and Chemotherapy. 2012 Jan;56(1):44-53.
2012-01
BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML
British Journal of Cancer. 2012 Jan;106(3):475-481.
2011-09-27
Formulations of indol-3-yl-2-oxoacetamide compounds
US8026271B2/2011-09-27
2011-08
BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells
PLoS ONE. 2011 Aug;6(8):Article number e23485.
2011-07
Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)
Bioorganic and Medicinal Chemistry. 2011 Jul;19(14):4173-4182 .
2011-04-28
Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents
Journal of Medicinal Chemistry. 2011 Apr 28;54(8):3076-3080.
2011-03-27
Design and synthesis of potent Aurora kinase inhibitors
Abstracts of Papers - American Chemical Society. 2011 Mar 27;241:258-MEDI.
2011-03
Comparative tissue distributions of cadmium chloride and cadmium-based quantum dot 705 in mice: Safety implications and applications
Nanotoxicology. 2011 Mar;5(1):91-97.
2011-03
Effect of shengmai san on insulin resistance, tumor necrosis factor-alpha and oxidative stress in rats fed on a high-fat diet
Journal of Food and Drug Analysis. 2011 Mar;19(1):40-48.
2011-03
Potent EGFR tyrosine kinase inhibitors as anticancer agents
Abstracts of Papers - American Chemical Society. 2011 Mar;241:257-MEDI.
2011-01-13
Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes
Journal of Medicinal Chemistry. 2011 Jan 13;54(1):166-178.
2011-01
BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities
Cancer Science. 2011 Jan;102(1):182-191.
2010-11
Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus
Antiviral Research. 2010 Nov;88(2):160-168.
2010-10-28
Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency
Journal of Medicinal Chemistry. 2010 Oct 28;53(20):7316-7326.
2010-10
Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities
Pharmacological Research. 2010 Oct;62(4):337-343.
2010-09-01
Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors
Bioorganic and Medicinal Chemistry. 2010 Sep ;18(17):6414-6421.
Showing items 101-125 of 152. (7 Page(s) Totally)
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