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显示项目51-75 / 98. (共4页) << < 1 2 3 4 > >> 每页显示[10|25|50]项目

日期	题名	關聯
2012-07	Induction of fatty acid oxidation resists weight gain, ameliorates hepatic steatosis and reduces cardiometabolic risk factors	International Journal of Obesity. 2012 Jul;36(7):999-1006.
2012-07	K2CO3/NaI-induced cyclization of omega-bromo alpha-cyano ketones: A new annulation approach for the formation of carbalkoxycyclohexane ring system	Synlett. 2012 Jul;23(11):1653-1656.
2012-05	Palladium(II) acetate mediated oxidative cyclization of omega-unsaturated alpha-cyano ketones for facile construction of methylenecyclohexane ring system	Organic & Biomolecular Chemistry. 2012 May;10(23):4609-4617.
2012-02	Discovery of novel stem cell mobilizers that target the CXCR4 receptor	ChemMedChem. 2012 Feb;7(2):209-212.
2011-10-01	硒吩化合物及其醫藥組成物	I349668/2011-10-01
2011-08-11	噁二唑化合物	I346662/2011-08-11
2011-07	Conia-ene annulation of the alpha-cyano Beta-TMS-capped alkynyl cycloalkanone system and its synthetic application	Organic and Biomolecular Chemistry. 2011 Jul;9(13):4778-4781.
2011-06	Hot topic: Opportunities and potential challenges for the treatment of metabolic syndrome	Current Topics In Medicinal Chemistry. 2011 Jun;11(12):1420.
2011-03-21	吡唑化合物及其醫藥組成物	I339205/2011-03-21
2011-03-04	Autoxidative annulation cascade of the alpha-cyano beta-TMS-capped alkynyl cycloalkanone system	Organic Letters. 2011 Mar 4;13(5):896-899.
2010-11-16	Thiophene compounds	US7834046B2/2010-11-16
2010-10	Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities	Pharmacological Research. 2010 Oct;62(4):337-343.
2010-09-28	Selenophene compounds	US7803799B2/2010-09-28
2010-09	Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophe n-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist	ChemMedChem. 2010 Sep;5(9):1439-1443.
2010-08	Total synthesis of (-)-Isopisiferin: Confirmation of absolute configuration	Journal of Organic Chemistry. 2010 Aug;2010(22):4271-4275.
2010-06	General approach to 2,3-dibenzyl-gamma-butyrolactone lignans: application to the total synthesis of (+/-)-5 '-methoxyyatein, (+/-)-5 '-methoxyclusin, and (+/-)-4 '-hydroxycubebinone	European Journal of Organic Chemistry. 2010 Jun;2010(18):3473-3480.
2010-04-27	Oxadiazole compounds	US7705024B2/2010-04-27
2010-02	Alpha-activated cross conjugated cycloalkenone systems in organic synthesis	Current Organic Synthesis. 2010 Feb;7(1):78-93.
2009-07-23	Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice	Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4496-4510.
2009-04-16	Polyene cyclization promoted by the cross-conjugated alpha-carbalkoxy cyclohexenone system. An unusual 1,2-hydride shift under lewis acid catalysis	Organic Letters. 2009 Apr 16;11(8):1673-1675.
2009	A concise total synthesis of (±)-acutifolone A	Organic and Biomolecular Chemistry. 2009;7(16):3285-3290.
2008-09-21	Bioisosteric replacement of the pyrazole 3-carboxamide moiety of rimonabant. A novel series of oxadiazoles as CB1 cannabinoid receptor antagonists	Organic and Biomolecular Chemistry. 2008 Sep 21;6(18):3399-3407.
2008-09-11	Bioisosteric replacement of the pyrazole 5-aryl moiety of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A). A novel series of alkynylthiophenes as potent and selective cannabinoid-1 receptor antagonists	Journal of Medicinal Chemistry. 2008 Sep 11;51(17):5397-5412.
2008-03	流感抗病毒藥物介紹	認識H5N1新型流感. 2008 Mar:41-46.
2008-02-07	Design, synthesis, and biological evaluation of novel alkenylthiophenes as potent and selective CB1 cannabinoid receptor antagonists	Organic and Biomolecular Chemistry. 2008 Feb;6(3):447-450.

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