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    近3年内发表的文件:90(8.93%)
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    显示项目301-350 / 1008. (共21页)
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    日期题名關聯
    2016-11-18 Cobalt(II)-catalyzed aerobic oxidation of terminal-capped alkynyl alpha-cyano alkanone systems. An oxygen-mediated radical chain reaction Journal of Organic Chemistry. 2016 Nov 18;81(22):10759-10768.
    2016-10 Cytotoxic cardenolides and sesquiterpenoids from the fruits of Reevesia formosana Phytochemistry. 2016 Oct;130:282-290.
    2016-10 BPR1J373, an oral multiple tyrosine kinase inhibitor, targets c-KIT for the treatment of c-KIT driven myeloid leukemia Molecular Cancer Therapeutics. 2016 Oct;15(10):2323-2333.
    2016-10 Multifunctional nanoparticles for oral protein drug delivery Diabetes Research and Clinical Practice. 2016 Oct;120(Suppl. 1):S19.
    2016-09 Mycotoxin patulin suppresses innate immune responses by mitochondrial dysfunction and p62/sequestosome-1-dependent mitophagy Journal of Biological Chemistry. 2016 Sep;291(37):19299-19311.
    2016-09 Activation of delta-opioid receptor contributes to the antinociceptive effect of oxycodone in mice Pharmacological Research. 2016 Sep;111:867-876.
    2016-08 Desferal regulates hCtr1 and transferrin receptor expression through Sp1 and exhibits synergistic cytotoxicity with platinum drugs in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo Oncotarget. 2016 Aug;7(31):49310-49321.
    2016-08 Dipeptidyl peptidase-4 inhibitor LAF-237 improves glucose tolerance and expends graft beta cell mass in diabetic mice transplanted with a sufficient number of islets Diabetologia. 2016 Aug;59(Suppl. 1):S198.
    2016-07-28 Design and synthesis of 1,2,3-triazole-containing N-acyl zanamivir analogs as potent neuraminidase inhibitors European Journal of Medicinal Chemistry. 2016 Jul 28;123:397-406.
    2016-07-22 Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons Nature Communications. 2016 Jul 22;7:Article number 12199.
    2016-07-01 MPT0B098, a microtubule inhibitor, suppresses JAK2/STAT3 signaling pathway through modulation of SOCS3 stability in oral squamous cell carcinoma PLoS ONE. 2016 Jul 1;11(7):Article number e0158440.
    2016-07 In vitro and in vivo studies of a potent capsid-binding inhibitor of enterovirus 71 Journal of Antimicrobial Chemotherapy. 2016 Jul;71(7):1922-1932.
    2016-07 Therapeutic polymeric nanoparticles and the methods of making and using thereof: A patent evaluation of WO2015036792 Expert Opinion on Therapeutic Patents. 2016 Jul;26(7):751-755.
    2016-07 Total synthesis of the naturally occurring glycosylflavone aciculatin Journal of Natural Products. 2016 Jul;79(7):1719-1723.
    2016-06 The sigma-1 receptor-zinc finger protein 179 pathway protects against hydrogen peroxide-induced cell injury Neuropharmacology. 2016 Jun;105:1-9.
    2016-05-19 Non-small-cell lung cancer cells combat epidermal growth factor receptor tyrosine kinase inhibition through immediate adhesion-related responses OncoTargets and Therapy. 2016 May 19;9:2961-2973.
    2016-05 N-Indolylglycosides bearing modifications at the glucose C6-Position as Sodium-Dependent Glucose Co-transporter 2 inhibitors Bioorganic and Medicinal Chemistry. 2016 May;24(10):2242-2250.
    2016-05 An early granulocyte colony-stimulating factor treatment attenuates neuropathic pain through activation of mu opioid receptors on the injured nerve Scientific Reports. 2016 May;6:Article number 25490.
    2016-04-12 Pyrazolylamine derivatives reveal the conformational switching between type I and type II binding modes of Anaplastic Lymphoma Kinase (ALK) Journal of Medicinal Chemistry. 2016 Apr 12;59(8):3906-3919.
    2016-04 Discovery and development of tylophorine derived dibenzoquinolines-33b compounds into therapeutic agents The FASEB Journal. 2016 Apr;30(1, Suppl.):Meeting Abstract lb56.
    2016-03 Probing for improved selectivity with dipeptide-derived inhibitors of dipeptidyl peptidases 8 and 9: The impact of P1-variation MedChemComm. 2016 Mar;7(3):433-438.
    2016-03 Disruption of protein-protein interactions: Hot spot detection, structure-based virtual screening and in vitro testing for the anti-cancer drug target survivin RSC Advances. 2016 Mar;6(38):31947-31959.
    2016-02-26 Using mutagenesis to explore conserved residues in the RNA-binding groove of influenza A virus nucleoprotein for antiviral drug development Scientific Reports. 2016 Feb 26;6:Article number 21662.
    2016-02-22 Guidelines for the use and interpretation of assays for monitoring autophagy [Erratum to: Autophagy. 2016 Jan 2;12(1):1-222.] Autophagy. 2016 Feb 22;12(2):443.
    2016-02 Antibacterial flavonoids from medicinal plants covalently inactivate type III protein secretion substrates Journal of the American Chemical Society. 2016 Feb 24;138(7):2209-2218.
    2016-02 Multifunctional nanoparticles for oral protein drug delivery Nanomedicine: Nanotechnology, Biology and Medicine. 2016 Feb;12(2):463.
    2016-01-02 Guidelines for the use and interpretation of assays for monitoring autophagy Autophagy. 2016 Jan 2;12(1):1-222.
    2016-01-01 Bispecific antibody conjugated manganese-based magnetic engineered iron oxide for imaging of HER2/neu- and EGFR-expressing tumors Theranostics. 2016 Jan 1;6(1):118-130.
    2016-01 Synthesis of (E)-oxindolylidene acetate using tandem palladium-catalyzed Heck and alkoxycarbonylation reactions Organic and Biomolecular Chemistry. 2016 Jan;14(1):220-228.
    2016-01 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition Organic and Biomolecular Chemistry. 2016 Jan;14(2):716-723.
    2016-01 Important hydrogen bond networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) inhibitor design revealed by crystal structures of imidazoleisoindole derivatives with IDO1 Journal of Medicinal Chemistry. 2016 Jan;59 (1):282-293.
    2016-01 Phenyl benzenesulfonylhydrazides exhibit selective Indoleamine 2,3-Dioxygenase inhibition with potent in vivo pharmacodynamic activity and antitumor efficacy Journal of Medicinal Chemistry. 2016 Jan;59(1):419-430.
    2015-12 The dnaJ gene as a molecular discriminator to differentiate among species and strain within the Lactobacillus casei group Molecular and Cellular Probes. 2015 Dec;29(6):479-484.
    2015-12 Simultaneous discrimination of species and strains in Lactobacillus rhamnosus using species-specific PCR combined with multiplex mini-sequencing technology Molecular and Cellular Probes. 2015 Dec;29(6):531-533.
    2015-12 Novel oxime-bearing coumarin derivatives act as potent Nrf2/ARE activators in vitro and in mouse model European Journal of Medicinal Chemistry. 2015 Dec;106:60-74.
    2015-10 Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening Journal of Medicinal Chemistry. 2015 Oct;58 (19):7807-7819.
    2015-09 O6-Methylguanine DNA methyltransferase repairs platinum-DNA adducts following cisplatin treatment and predicts prognoses of nasopharyngeal carcinoma International Journal of Cancer. 2015 Sep;137(6):1291-1305.
    2015-09 Self-assembling bubble carriers for oral protein delivery Biomaterials. 2015 Sep;64:115-124.
    2015-08-14 Studies on antibiotics active against resistant bacteria. Total synthesis of MRSA-active tetarimycin A and its analogues Organic Letters. 2015 Aug 14;17(17):4248-4251.
    2015-08 Sun1 deficiency leads to cerebellar ataxia in mice Disease Models and Mechanisms. 2015 Aug;8(8):957-967.
    2015-08 Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes Bioorganic and Medicinal Chemistry. 2015 Aug;23(15):4230-4236.
    2015-08 Novel Nrf2/ARE activator, trans-coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38alpha/MAPKAPK-2 and PK-N3 signaling pathway Chemical Research in Toxicology. 2015 Aug ;28(9):1681-1692.
    2015-08 BPR2P001S0, a Coumarin derivative, induced cell cycle arrest in A549 through inhibiting PDPK1 activity Cancer Research. 2015 Aug;75:Abstract number 1754.
    2015-08 Zinc-dipicolylamine directed pharmaceutical delivery system (ZAPS) as an innovative cancer drug delivery platform Cancer Research. 2015 Aug;75(Suppl. 15):Abstract number 4413.
    2015-08 Optimization of quinazoline-based kinase inhibitors: Identification of a dual FLT3/AURKA kinase inhibitor for the treatment of acute myeloid leukemia Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 490.
    2015-08 Optimization of furanopyrimidine-based kinase inhibitors: Identification of a BTK kinase inhibitor for the treatment of B cell lymphoma Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 180.
    2015-08 Discovery of 2,4-diaminopyrimidines bearing a unique pharmacophore as anaplastic lymphoma kinase inhibitors Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 182.
    2015-07-31 作為極光激酶抑制劑的稠合雙環嘧啶化合物 HK1151694/2015-07-31
    2015-07-29 脯氨酸衍生物 ZL201080002506.6/2015-07-29
    2015-07-22 作为酪胺酸激酶抑制剂的稠合双环及多环嘧啶化合物 ZL200980144458.1/2015-07-22

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