| 2019-07-03 |
Delineating the active site architecture of G9a lysine methyltransferase through substrate and inhibitor binding mode analysis: A molecular dynamics study |
Journal of Biomolecular Structure and Dynamics. 2019 Jul 3;37(10):2581-2592. |
 |
| 2019-07 |
Nucleoside analogs with selective antiviral activity against dengue fever and Japanese encephalitis viruses |
Antimicrobial Agents and Chemotherapy. 2019 Jul;63(7):e00397-19. |
|
| 2019-07 |
Citronellol induces necroptosis of human lung cancer cells via TNF-alpha pathway and reactive oxygen species accumulation |
In Vivo. 2019 Jul-Aug;33(4):1193-1201. |
|
| 2019-07 |
Dual Kit/Aur inhibitors as chemosensitizing agents for the treatment of melanoma: Design, synthesis, docking studies and functional investigation |
Scientific Reports. 2019 Jul;9:Article number 9943. |
|
| 2019-07 |
Use of integrated genomic analyses in patient-derived tumor model to discover new clinical indications for the multikinase inhibitor drug candidate, DBPR216 |
Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 4626. |
|
| 2019-07 |
BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy |
Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 227. |
|
| 2019-07 |
An Aurora kinase inhibitor BPR6K471 inhibits tumor growth and reduces the cancer stem cell-like properties of small cell lung cancer |
Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 3851. |
|
| 2019-06-15 |
Strategies for improving diabetic therapy via alternative administration routes that involve stimuli-responsive insulin-delivering systems |
Advanced Drug Delivery Reviews. 2019 Jan 15;139(SI):71-82. |
|
| 2019-06-05 |
Delta-opioid receptor antagonist naltrindole reduces oxycodone addiction and constipation in mice |
European Journal of Pharmacology. 2019 Jun 5;852:265-273. |
|
| 2019-06 |
Identification of the PCA29 gene signature as a predictor in prostate cancer |
Journal of Bioinformatics and Computational Biology. 2019 Jun;17(3, SI):Article number 1940006. |
|
| 2019-05-29 |
Insights for the design of protein lysine methyltransferase G9a inhibitors |
Future Medicinal Chemistry. 2019 May 29;11(9):993-1014. |
|
| 2019-05-28 |
Identification of novel anti-liver cancer small molecules with better therapeutic index than sorafenib via zebrafish drug screening platform |
Cancers. 2019 May 28;11(6):Article number 739. |
|
| 2019-05 |
Synthesis and evaluation of novel 7H-pyrrolo-[2,3-d]pyrimidine derivatives as potential anticancer agents |
Future Medicinal Chemistry. 2019 May;11(9):959-974. |
|
| 2019-05 |
Characterization, dynamics, and mechanism of CXCR4 antagonists on a constitutively active mutant |
Cell Chemical Biology. 2019 May;26(5):662-673.e7. |
|
| 2019-05 |
A novel mechanism of miRNA-mediated CBX8 associated with tumorigenesis in head and neck squamous cell carcinoma |
Journal of Clinical Oncology. 2019 May;37(15, Suppl. S):Abstract number e17534. |
|
| 2019-04-10 |
Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants |
Journal of Medicinal Chemistry. 2019 Apr 10;62(8):3940-3957. |
|
| 2019-04-01 |
A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus |
European Journal of Medicinal Chemistry. 2019 Apr 1;167:245-268. |
|
| 2019-04-01 |
The in vivo antinociceptive and mu-opioid receptor activating effects of the combination of N-phenyl-2′,4′-dimethyl-4,5′-bi-1,3-thiazol-2-amines and naloxone |
European Journal of Medicinal Chemistry. 2019 Apr 1;167:312-323. |
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| 2019-03-28 |
Phase-changeable nanoemulsions for oral delivery of a therapeutic peptide: Toward targeting the pancreas for antidiabetic treatments using lymphatic transport |
Advanced Functional Materials. 2019 Mar 28;29(13): Article number 1809015. |
|
| 2019-03-15 |
Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation |
Communications Biology. 2019 Mar 15;2:Article number 105. |
|
| 2019-03-01 |
Interference of DNAJB6/MRJ isoform switch by morpholino inhibits replication of HIV-1 and RSV |
Molecular Therapy. Nucleic Acids. 2019 Mar 1;14:251-261. |
|
| 2019-03 |
Synthesis and biological evaluation of N-glucosyl indole derivatives as sodium-dependent glucose co-transporter 2 inhibitors |
Bioorganic Chemistry. 2019 Mar;83:520-525. |
|
| 2019-03 |
Mutagenesis of the dengue virus NS4A protein reveals a novel cytosolic N-terminal domain responsible for virus-induced cytopathic effects and intramolecular interactions within the N-terminus of NS4A |
Journal of General Virology. 2019 Mar;100(3):457-470. |
|
| 2019-02-20 |
Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice |
Scientific Reports. 2019 Feb 20;9:Article number 2405. |
|
| 2019-01-03 |
KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC |
Oncogene. 2019 Jan 3;38(1):17-32. |
|
| 2019-01-01 |
Fluorine-18 isotope labeling for positron emission tomography imaging. Direct evidence for DBPR211 as a peripherally restricted CB1 inverse agonist |
Bioorganic and Medicinal Chemistry. 2019 Jan 1;27(1):216-223. |
|
| 2019-01 |
CSC-3436 inhibits TWIST-induced epithelial-mesenchymal transition via the suppression of Twist/Bmi1/Akt pathway in head and neck squamous cell carcinoma |
Journal of Cellular Physiology. 2019 Jan;234(6):9118-9129. |
|
| 2019-01 |
CCM111 prevents hepatic fibrosis via cooperative inhibition of TGF-Beta Wnt and STAT3 signaling pathways |
Journal of Food and Drug Analysis. 2019 Jan;27(1):184-194. |
|
| 2018-12-07 |
Temperature-controlled thiation of alpha-Cyano-beta-Alkynyl carbonyl derivatives for de vovo synthesis of 2-Aminothiophenes and thieno[2,3- c]isothiazoles |
Journal of Organic Chemistry. 2018 Dec 7;83(23):14688-14697. |
|
| 2018-12 |
Helicobacter pylori cholesterol glucosylation modulates autophagy for increasing intracellular survival in macrophages |
Cellular Microbiology. 2018 Dec;20(12):Article number e12947. |
|
| 2018-12 |
Ubiquitin-conjugating enzyme E2 B regulates the ubiquitination of O(6)-methylguanine-DNA methyltransferase and BCNU sensitivity in human nasopharyngeal carcinoma cells |
Biochemical Pharmacology. 2018 Dec;158:327-338. |
|
| 2018-12 |
Dendritic cell-derived exosomes increase the efficacy of anti-PD-L1 antibody in melanoma model |
Cancer Science. 2018 Dec;109(Suppl. 2):1322. |
|
| 2018-12 |
Establishment and characterization of novel syngeneic oral squamous cell carcinoma mouse cell lines |
Cancer Science. 2018 Dec;109(Suppl. 2):386. |
|
| 2018-12 |
Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer |
Cancer Science. 2018 Dec;109(SI, Suppl. 2):210. |
|
| 2018-12 |
Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer |
Cancer Science. 2018 Dec;109(Suppl. 2, SI):1257. |
|
| 2018-11 |
Biomimetic Syntheses of (±)‐Isopalhinine A, (±)‐Palhinine A, and (±)‐Palhinine D |
Angewandte Chemie. 2018 Nov;57(47):15572-15576. |
|
| 2018-10-26 |
Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction |
Communications Biology. 2018 Oct 26;1:Article number 178. |
|
| 2018-10-06 |
Median nerve stimulation induces analgesia via orexin-initiated endocannabinoid disinhibition in the periaqueductal gray |
Proceedings of the National Academy of Sciences of the United States of America. 2018 Nov;115(45):E10720-E10729. |
|
| 2018-10 |
The cardenolide ouabain suppresses coronaviral replication via augmenting a Na(+)/K(+)-ATPase-dependent PI3K_PDK1 axis signaling |
Toxicology and Applied Pharmacology. 2018 Oct;56:90-97. |
|
| 2018-10 |
Identification of novel Cdc7 kinase inhibitors as anti-cancer agents that target the interaction with Dbf4 by the fragment complementation and drug repositioning approach |
EBioMedicine. 2018 Oct;36:241-251. |
|
| 2018-10 |
Identification of the PCa28 gene signature as a predictor in prostate cancer |
Proceedings 2018 Ieee 18th International Conference on Bioinformatics and Bioengineering. 2018 Oct:155-158. |
|
| 2018-09 |
Development of robust genotype 1a hepatitis C replicons harboring adaptive mutations for facilitating the antiviral drug discovery and study of virus replication |
Journal of Virological Methods. 2018 Sep;259:10-17. |
|
| 2018-08-24 |
BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor |
Cancer Science. 2018 Nov;109(11):3591-3601. |
|
| 2018-08-23 |
5-aroylindoles act as selective histone deacetylase 6 inhibitors ameliorating alzheimer's disease phenotypes |
Journal of Medicinal Chemistry. 2018 Aug 23;61(16):7087-7102. |
|
| 2018-08-21 |
DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation |
Proceedings of the National Academy of Sciences of the United States of America. 2018 Aug 21;115(34):E8027-E8036. |
|
| 2018-08-04 |
Upregulation of Znf179 acetylation by SAHA protects cells against oxidative stress |
Redox Biology. 2018 Aug 4;19:74-80. |
|
| 2018-08 |
Auroramycin: A potent antibiotic from streptomyces roseosporus by CRISPR-Cas9 activation |
Chembiochem: A European Journal of Chemical Biology. 2018 Aug;19(16):1716-1719. |
|
| 2018-07-26 |
The conserved stem-loop II structure at the 3' untranslated region of Japanese encephalitis virus genome is required for the formation of subgenomic flaviviral RNA |
PLoS ONE. 2018 Jul 26;13(7):Article number e0201250. |
|
| 2018-07 |
Harnessing CXCR4 antagonists in stem cell mobilization, HIV infection, ischemic diseases, and oncology |
Medicinal Research Reviews. 2018 Jul;38(4):1188-1234. |
|
| 2018-07 |
Synergic effect of curcumin and its structural analogue (Monoacetylcurcumin) on anti-influenza virus infection |
Journal of Food and Drug Analysis. 2018 Jul;26(3):1015-1023. |
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