| 2020-08-19 |
Lamin A-mediated nuclear lamina integrity is required for proper ciliogenesis |
EMBO Reports. 2020 Oct 05;21(10):Article number e49680. |
 |
| 2020-08 |
Two new diprenylated flavanones from Derris laxiflora Benth |
Natural Product Research. 2020 Aug;34(15):2101-2108. |
|
| 2020-08 |
Design of a potent anticancer lead inspired by natural products from traditional Indian medicine |
Journal of Biomolecular Structure and Dynamics. 2020 Aug;38(12):3563-3577. |
|
| 2020-08 |
Polyketide synthase gene expression in relation to chloromonilicin and melanin production in Monilinia fructicola |
Phytopathology. 2020 Aug;110(8):1465-1475. |
|
| 2020-08 |
Artificial intelligence approach fighting COVID-19 with repurposing drugs |
Biomedical Journal. 2020 Aug;43(4):355-362. |
|
| 2020-08 |
Repurposing old drugs as antiviral agents for coronaviruses |
Biomedical Journal. 2020 Aug;43(4):368-374. |
|
| 2020-08 |
BPR6K609: An Aurora kinase inhibitor targeting small cell lung cancer with MYC amplification |
Cancer Research. 2020 Aug;80(16):1937. |
|
| 2020-07-22 |
Globo H-KLH vaccine adagloxad simolenin (OBI-822)/OBI-821 in patients with metastatic breast cancer: Phase II randomized, placebo-controlled study |
Journal for Immunotherapy of Cancer. 2020 Jul 22;8(2):Article number e000342. |
|
| 2020-07-11 |
Granulocyte Colony Stimulating Factor (GCSF) can attenuate neuropathic pain by suppressing monocyte Chemoattractant Protein-1 (MCP-1) expression, through upregulating the early MicroRNA-122 expression in the dorsal root ganglia |
Cells. 2020 Jul 11;9(7):Article number 1669. |
|
| 2020-07 |
Design of drug-like hepsin inhibitors against prostate cancer and kidney stones |
Acta Pharmaceutica Sinica B. 2020 Jul;10(7):1309-1320. |
|
| 2020-06-02 |
Zika virus NS3 protease pharmacophore anchor model and drug discovery |
Scientific Reports. 2020 Jun 2;10:Article number 8929. |
|
| 2020-06 |
Morphine produces potent antinociception, sedation, and hypothermia in humanized mice expressing human mu opioid receptor splice variants |
Pain. 2020 Jun;161(6):1177-1190. |
|
| 2020-05 |
Antiviral activity of llama-inspired single domain antibody against Enterovirus A71 |
Antimicrobial Agents and Chemotherapy. 2020 May;64(5):Article number e01922-19. |
|
| 2020-05 |
Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors |
Bioorganic Chemistry. 2020 May;98:Article number 103689. |
|
| 2020-04-15 |
Betulinic acid-mediated tuning of PERK/CHOP signaling by Sp1 inhibition as a novel therapeutic strategy for glioblastoma |
Cancers. 2020 Apr 15;12(4):Article number 981. |
|
| 2020-04-02 |
MiR-30a and miR-379 modulate retinoic acid pathway by targeting DNA methyltransferase 3B in oral cancer |
Journal of Biomedical Science. 2020 Apr 2;27:Article number 46. |
|
| 2020-04 |
BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine |
Neuropharmacology. 2020 Apr;166:Article number 107678. |
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| 2020-04 |
Development of a cross-conjugated vinylogous [4+2] anionic annulation and application to the total synthesis of natural antibiotic (±)-ABX |
Angewandte Chemie. 2020 Apr;59(16):6540-6545. |
|
| 2020-04 |
Pharmacological studies of morphine in a novel humanized mu opioid receptor mouse model |
FASEB Journal. 2020 Apr;34(S1):Abstract number 02835. |
|
| 2020-03-01 |
A selective Aurora-A 5'-UTR siRNA inhibits tumor growth and metastasis |
Cancer Letters. 2020 Mar 1;472:97-107. |
|
| 2020-03-01 |
Chalcone synthesis, properties and medicinal applications: A review |
Environmental Chemistry Letters. 2020 Mar 1;18(2):433-458. |
|
| 2020-03 |
Upregulation of Cisd2 attenuates Alzheimer's related neuronal loss in mice |
Journal of Pathology. 2020 Mar;250(2):299-311. |
|
| 2020-02-18 |
Impacts of intralipid on nanodrug abraxane therapy and on the innate immune system |
Scientific Reports. 2020 Feb 18;10:Article number 2838. |
|
| 2020-02-10 |
Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors |
Journal of Medicinal Chemistry. 2020 Feb 10;63(4):1642-1659. |
|
| 2020-02-01 |
Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment |
European Journal of Medicinal Chemistry. 2020 Feb 1;187:Article number 111915. |
|
| 2020-02 |
The cardenolides ouabain and reevesioside A promote FGF2 secretion and subsequent FGFR1 phosphorylation via converged ERK1/2 activation |
Biochemical Pharmacology. 2020 Feb;172:Article number 113741. |
|
| 2020-02 |
Design, synthesis and anticancer evaluation of beta-carboline-1-one hydantoins |
Future Medicinal Chemistry. 2020 Feb;12(3):183-192. |
|
| 2020-02 |
Tylophorine-based compounds are therapeutic in rheumatoid arthritis by targeting the caprin-1 ribonucleoprotein complex and inhibiting expression of associated c-Myc and HIF-1alpha |
Pharmacological Research. 2020 Feb;152:Article number 104581. |
|
| 2020-01-16 |
Development of a cross-conjugated vinylogous [4+2] anionic annulation and application to the total synthesis of natural antibiotic (±)-ABX |
Advanced Materials. 2020 Jan 16;132(16):6602-6607. |
|
| 2020-01-06 |
Biosynthetic engineering of the antifungal, anti-MRSA auroramycin |
Microbial Cell Factories. 2020 Jan 6;19:Article number 3. |
|
| 2020-01-01 |
Delayed intervention with a novel SGLT2 inhibitor NGI001 suppresses diet-induced metabolic dysfunction and nonalcoholic fatty liver disease in mice |
British Journal of Pharmacology. 2020 Jan 1;177(2):239-253. |
|
| 2020-01 |
Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening |
Biochimie. 2020 Jan;168:220-230. |
|
| 2019-12-24 |
ERK activation modulates cancer stemness and motility of a novel mouse oral squamous cell carcinoma cell line |
Cancers. 2019 Dec 24;12(1):Article number 61. |
|
| 2019-12 |
Lysosomal cysteine protease cathepsin S is involved in cancer cell motility by regulating store-operated Ca(2+) entry |
Biochimica et Biophysica Acta. Molecular Cell Research. 2019 Dec;1866(12):Article number 118517. |
|
| 2019-12 |
A novel flavivirus entry inhibitor, BP34610, discovered through high-throughput screening with dengue reporter viruses |
Antiviral Research. 2019 Dec;172:Article number 104636. |
|
| 2019-12 |
Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis |
Aging Cell. 2019 Dec;Article number e13090. |
|
| 2019-12 |
Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia |
Journal of Medicinal Chemistry. 2019 Dec;62(24):11135-11150. |
|
| 2019-11-27 |
Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer |
Journal of Medicinal Chemistry. 2019 Nov 27;62(22):10108-10123. |
|
| 2019-10-08 |
Identification of two novel small compounds that inhibit liver cancer formation in zebrafish and analysis of their conjugation to nanodiamonds to further reduce toxicity |
Advanced Therapeutics. 2019 Oct 8;2(12):Article number 1900105. |
|
| 2019-10 |
In vivo efficacy of cannabinoid receptor 1 antagonist, CPD1, in treating non-alcoholic fatty liver disease |
Hepatology. 2019 Oct;70:1333A. |
|
| 2019-10 |
Discovery of clinical candidate DBPR112, a furanopyrimidine-based epidermal growth factor receptor inhibitor for the treatment of non-small cell lung cancer |
Annals of Oncology. 2019 Oct;30(Suppl. 5):789. |
|
| 2019-10 |
The molecular mechanisms of EpCAM in regulating tumor progression and development of anti-EpCAM antibodies for colon cancer diagnosis and therapy |
Annals of Oncology. 2019 Oct;30(Suppl. 5):786. |
|
| 2019-10 |
Inhibition of Rspo-Wnt pathway facilitates checkpoint blockade therapy by anti-RSPO3 antibody (DBPR117) |
Annals of Oncology. 2019 Oct;30(Suppl. 5):191. |
|
| 2019-09 |
Effects of boschnaloside from Boschniakia rossica on dysglycemia and islet dysfunction in severely diabetic mice through modulating the action of glucagon-like peptide-1 |
Phytomedicine. 2019 Sep;62:Article number 152946. |
|
| 2019-08-27 |
A dengue virus type 2 (DENV-2) NS4B-interacting host factor, SERP1, reduces DENV-2 production by suppressing viral RNA replication |
Viruses. 2019 Aug 27;11(9):Article number 787. |
|
| 2019-08-15 |
Sun1 mediates interkinetic nuclear migration and Notch signaling in the neurogenesis of zebrafish |
Stem Cells and Development. 2019 Aug 15;28(16):1116-1127. |
|
| 2019-08-06 |
Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: An identification of a novel oncotarget[Erratum: Oncotarget. 2015 Feb;6(4):2148-2163.] |
Oncotarget. 2019 Aug 6;10(47):4919. |
|
| 2019-08 |
A structure-function approach identifies L-PGDS as a mediator responsible for glucocorticoid-induced leptin expression in adipocytes |
Biochemical Pharmacology. 2019 Aug;166:203-211. |
|
| 2019-08 |
Melatonin promotes neuroblastoma cell differentiation by activating hyaluronan synthase 3-induced mitophagy |
Cancer Medicine. 2019 Aug;8(10):4821-4835. |
|
| 2019-07-11 |
Linker optimization and therapeutic evaluation of phosphatidylserine-targeting zinc dipicolylamine-based drug conjugates |
Journal of Medicinal Chemistry. 2019 Jul 11;62(13):6047-6062. |
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