| 2014-02 |
Epstein-Barr virus BALF3 has nuclease activity and mediates mature virion production during the lytic cycle |
Journal of Virology. 2014 Feb;88(9):4962-4975. |
 |
| 2014-01-08 |
Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer |
PLoS ONE. 2014 Jan 8;9(1):Article number e83160. |
|
| 2013-12 |
Evolutionarily conserved residues at an oligomerization interface of the influenza A virus neuraminidase are essential for viral survival |
Virology. 2013 Dec;447(1-3):32-44. |
|
| 2013-10-01 |
喹啉化合物及包含其之治療病毒感染之醫藥組成物 |
I410245/2013-10-01 |
|
| 2013-09-22 |
A novel Aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatment [Erratum:International Journal of Biological Sciences. 2013 Apr 29;9(4):403-411] |
International Journal of Biological Sciences. 2013 Sep 22;9(9):947. |
|
| 2013-08-13 |
Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors |
US8507502B2/2013-08-13 |
|
| 2013-06-28 |
Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor |
Journal of Medicinal Chemistry. 2013 Jun 28;56(13):5247-5260. |
|
| 2013-06 |
Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) |
Bioorganic and Medicinal Chemistry. 2013 Jun;21(11):2856-2867. |
|
| 2013-06 |
Synthesis of acylguanidine zanamivir derivatives as neuraminidase inhibitors and the evaluation of their bio-activities |
Organic and Biomolecular Chemistry. 2013 Jun;11(24):3943-3948. |
|
| 2013-05 |
Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules |
Proceedings of the National Academy of Sciences of the United States of America. 2013 May;110(19):E1779-E1787. |
|
| 2013-05 |
Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors |
Journal of Medicinal Chemistry. 2013 May;56(10):3889-3903. |
|
| 2013-04-29 |
A novel Aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatment |
International Journal of Biological Sciences. 2013 Apr 29;9(4):403-411. |
|
| 2013-04-07 |
BPR000K, a novel Aurora kinase inhibitor |
Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 300-MEDI. |
|
| 2013-04-07 |
3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor |
Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 87-MEDI. |
|
| 2013-04-07 |
Development drug candidate targeting EGFR kinase: DBPR112 |
Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 299-MEDI. |
|
| 2013-04 |
Design and synthesis of Aurora kinase inhibitors as anticancer agents |
Abstracts of Papers - American Chemical Society. 2013 Apr;245:Article number 301-MEDI. |
|
| 2013-02-20 |
Parallel screening of Wild-Type and drug-resistant targets for anti-resistance neuraminidase inhibitors |
PLoS ONE. 2013 Feb 20;8(2):Article number e56704. |
|
| 2013-02-11 |
作為酪胺酸激酶抑制劑之稠合雙環及多環嘧啶化合物 |
I385174/2013-02-11 |
|
| 2013-02 |
Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems |
Antimicrobial Agents and Chemotherapy. 2013 Feb; 57(2):723-733. |
|
| 2013-01 |
3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor |
ChemMedChem. 2013 Jan;8(1):136-148. |
|
| 2012-12 |
An efficient, mild and scalable synthesis of bioactive compounds containing the angelicin scaffold |
Journal of the Chinese Chemical Society. 2012 Dec;59(12):1548-1554. |
|
| 2012-11-07 |
Enhanced recombinant protein production and differential expression of molecular chaperones in sf-caspase-1-repressed stable cells after baculovirus infection |
BMC Biotechnology. 2012 Nov 7;12(1):Ariticle number 83. |
|
| 2012-11 |
BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia |
European Journal of Cancer. 2012 Nov;48(Suppl. 6):53-54. |
|
| 2012-09 |
Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization |
ChemMedChem. 2012 Sep;7(9):1546-1550. |
|
| 2012-08 |
Development of an anti-influenza drug screening assay targeting nucleoproteins with tryptophan fluorescence quenching |
Analytical Chemistry. 2012 Aug;84(15):6391-6399. |
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