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Development of a humanized antibody...
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2013-08-13
Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors
US8507502B2/2013-08-13
2013-06-28
Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor
Journal of Medicinal Chemistry. 2013 Jun 28;56(13):5247-5260.
2013-06
Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)
Bioorganic and Medicinal Chemistry. 2013 Jun;21(11):2856-2867.
2013-06
Synthesis of acylguanidine zanamivir derivatives as neuraminidase inhibitors and the evaluation of their bio-activities
Organic and Biomolecular Chemistry. 2013 Jun;11(24):3943-3948.
2013-05
Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules
Proceedings of the National Academy of Sciences of the United States of America. 2013 May;110(19):E1779-E1787.
2013-05
Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors
Journal of Medicinal Chemistry. 2013 May;56(10):3889-3903.
2013-04-29
A novel Aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatment
International Journal of Biological Sciences. 2013 Apr 29;9(4):403-411.
2013-04-07
BPR000K, a novel Aurora kinase inhibitor
Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 300-MEDI.
2013-04-07
3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor
Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 87-MEDI.
2013-04-07
Development drug candidate targeting EGFR kinase: DBPR112
Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 299-MEDI.
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