國家衛生研究院 NHRI:Items for Author
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    Items for Author "Peng, YH" 

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    Showing 25 items.

    Collection Date Title Relation Bitstream
    [伍素瑩] 期刊論文 2020-02-10 Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors -
    [伍素瑩] 期刊論文 2019-04-10 Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants -
    [伍素瑩] 期刊論文 2016-04-12 Pyrazolylamine derivatives reveal the conformational switching between type I and type II binding modes of Anaplastic Lymphoma Kinase (ALK) -
    [伍素瑩] 期刊論文 2016-01 Important hydrogen bond networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) inhibitor design revealed by crystal structures of imidazoleisoindole derivatives with IDO1 -
    [伍素瑩] 期刊論文 2015-10 Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening -
    [伍素瑩] 期刊論文 2006-08-24 Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease -
    [伍素瑩] 期刊論文 2006-05-04 Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities -
    [吳嘉文] 期刊論文 2024-06-07 Enhancing ionic selectivity and osmotic energy by using an ultrathin Zr-MOF-based heterogeneous membrane with trilayered continuous porous structure -
    [徐祖安] 期刊論文 2013-05 Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors -
    [翁紹華] 期刊論文 2022-02-05 Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design -
    [翁紹華] 期刊論文 2016-01 Phenyl benzenesulfonylhydrazides exhibit selective Indoleamine 2,3-Dioxygenase inhibition with potent in vivo pharmacodynamic activity and antitumor efficacy -
    [蔣維棠] 期刊論文 2019-12 Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia -
    [蘇益仁(2002-2015)] 期刊論文 2017-03-21 Low-cell-number, single-tube amplification (STA) of total RNA revealed transcriptome changes from pluripotency to endothelium -
    [許惠恒] 期刊論文 2024-02-13 Age at onset of type 1 diabetes between puberty and 30 years old is associated with increased diabetic nephropathy risk -
    [謝興邦] 會議論文/會議摘要 2005-03 Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents -
    [謝興邦] 期刊論文 2019-11-27 Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer -
    [謝興邦] 期刊論文 2013-05 Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules -
    [謝興邦] 期刊論文 2010-06-15 Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification -
    [謝興邦] 期刊論文 2009-04-23 Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists -
    [謝興邦] 期刊論文 2006-10-19 Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists -
    [謝興邦] 期刊論文 2006-02-09 Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies -
    [謝興邦] 期刊論文 2005-12-29 Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities -
    [趙宇生(2002-2013)] 期刊論文 2010-10 Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists -
    [郭靜娟] 期刊論文 2021-08-12 Xanthine derivatives reveal an allosteric binding site in methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) -
    [陳炯東] 期刊論文 2010-12 Discovery of non-glycoside sodium-dependent glucose Co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening -

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