國家衛生研究院 NHRI:Item 3990099045/9628

NHRI > National Institute of Environmental Health Sciences > Saou-Hsing Liou > Periodical Articles > Item 3990099045/9628

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/9628

Title:	Increased levels of oxidative stress biomarkers in metal oxides nanomaterial-handling workers
Authors:	Liou, SH;Chen, YC;Liao, HY;Wang, CJ;Chen, JS;Lee, HL
Contributors:	National Institute of Environmental Health Sciences
Abstract:	This study assessed oxidatively damaged DNA and antioxidant enzyme activity in workers occupational exposure to metal oxides nanomaterials. Exposure to TiO2, SiO2, and ITO resulted in significant lower antioxidant enzymes (glutathione peroxidase and superoxide dismutase) and higher oxidative biomarkers 8-hydroxydeoxyguanosine (8-oxodG) than comparison workers. Statistically significant correlations were noted between plasma and urine 8-oxodG, between white blood cells (WBC) and urine 8-oxodG, and between WBC and plasma 8-oxodG. In addition, there were significant negative correlations between WBC 8-oxodG and SOD and between urinary 8-oxodG and GPx levels. The results showed that urinary 8-oxodG may be considered to be better biomarker.
Date:	2016-11
Relation:	Biomarkers. 2016 Nov;21(7):600-606.
Link to:	http://dx.doi.org/10.3109/1354750x.2016.1160432
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1354-750X&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000385399600004
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84961392278
Appears in Collections:	[Saou-Hsing Liou] Periodical Articles

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