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2024-09-10
Boosting DNA vaccine power by lipid nanoparticles surface engineered with amphiphilic bioresorbable copolymer
Molecular Therapy Nucleic Acids. 2024 Sep 10;35(3):Article number 102261.
2024-03-14
Lipid nanoparticle-encapsulated DNA vaccine robustly induce superior immune responses to the mRNA vaccine in Syrian hamsters
Molecular Therapy Methods and Clinical Development. 2024 Mar 14;32(1):Article number 101169.
2024-03
Inhibition of ADAM9 promotes the selective degradation of KRAS and sensitizes pancreatic cancers to chemotherapy
Nature Cancer. 2024 Mar;5(3):400-419.
2024
ADAM9 drives the immunosuppressive microenvironment by cholesterol biosynthesis-mediated activation of IL6-STAT3 signaling for lung tumor progression
American Journal of Cancer Research. 2024;14(4):1850-1865.
2023-12
A broad-spectrum pneumococcal vaccine induces mucosal immunity and protects against lethal Streptococcus pneumoniae challenge
Emerging Microbes and Infections. 2023 Dec;12(2):Article number 2272656.
2023-08-27
Co-delivery of a trimeric spike DNA and protein vaccine with aluminum hydroxide enhanced Th1-dominant humoral and cellular immunity against SARS-CoV-2
Journal of Medical Virology. 2023 Aug 27;95(8):Article number e29040.
2023-08-16
A TLR9 agonist synergistically enhances protective immunity induced by an Alum-adjuvanted H7N9 inactivated whole-virion vaccine
Emerging Microbes and Infections. 2023 Aug 16;12(2):Article number 2249130.
2023-08
Humoral and cellular immunity in three different types of COVID-19 vaccines against SARS-CoV-2 variants in a real-world data analysis
Journal of Microbiology, Immunology and Infection. 2023 Aug;56(4):705-717.
2023-06-02
Recombinant lipidated FLIPr effectively enhances mucosal and systemic immune responses for various vaccine types
npj Vaccines. 2023 Jun 02;8:Article number 82.
2023-05-29
TLR9 and STING agonists cooperatively boost the immune response to SARS-CoV-2 RBD vaccine through an increased germinal center B cell response and reshaped T helper responses
International Journal of Biological Sciences. 2023 May 29;19(9):2897-2913.
2023-01-23
A flexible liposomal polymer complex as a platform of specific and regulable immune regulation for individual cancer immunotherapy
Journal of Experimental and Clinical Cancer Research. 2023 Jan 23;42:Article number 29.
2022-12-02
Omicron-specific mRNA vaccine induced cross-protective immunity against ancestral SARS-CoV-2 infection with low neutralizing antibodies
Journal of Medical Virology. 2022 Dec 2;95:Article number e28370.
2022-11-21
Formulation of SARS-CoV-2 spike protein with CpG oligodeoxynucleotides and squalene nanoparticles modulates immunological aspects following intranasal delivery
Pharmaceutics. 2022 Nov 21;14(11):Article number 2539.
2022-06-09
Induction of high affinity monoclonal antibodies against SARS-CoV-2 variant infection using a DNA prime-protein boost strategy
Journal of Biomedical Science. 2022 Jun 9;29:Article number 37.
2022-06-03
A DNA vaccine candidate delivered by an electroacupuncture machine provides protective immunity against SARS-CoV-2 infection
npj Vaccines. 2022 Jun 03;7:Article number 60.
2022-05-02
Furin and TMPRSS2 resistant spike induces robust humoral and cellular immunity against SARS-CoV-2 lethal infection
Frontiers in Immunology. 2022 May 2;13:Article number 872047.
2022-04-28
Low-dose SARS-CoV-2 S-trimer with an emulsion adjuvant induced th1-biased protective immunity
International Journal of Molecular Sciences. 2022 Apr 28;23(9):Article number 4902.
2022-04-22
Monoclonal antibody targeting the conserved region of the SARS-CoV-2 spike protein to overcome viral variants
JCI Insight. 2022 Apr 22;7(8):Article number e157597.
2021-10-11
Intranasal vaccination with recombinant antigen-FLIPr fusion protein alone induces long-lasting systemic antibody responses and broad T cell responses
Frontiers in Immunology. 2021 Oct 11;12:Article number 751883.
2021-10-05
A novel rapid test to detect anti-SARS-CoV-2 n protein IgG based on shear horizontal surface acoustic wave (SH-SAW)
Diagnostics. 2021 Oct 5;11(10):Article number 1838.
2021-10
Activation of GM-CSF and TLR2 signaling synergistically enhances antigen-specific antitumor immunity and modulates the tumor microenvironment
Journal for Immunotherapy of Cancer. 2021 Oct;9(10):Article number e002758.
2021-09-25
Assessment of adjuvantation strategy of lipid squalene nanoparticles for enhancing the immunogenicity of a SARS-CoV-2 spike subunit protein against COVID-19
International Journal of Pharmaceutics. 2021 Sep 25;607:Article number 121024.
2021-09
Squalene nanoemulsion reinforces mucosal and immunological fingerprints following intravaginal delivery
Biomedicine and Pharmacotherapy. 2021 Sep;141:Article number 111799.
2021-08-11
Characterization of virus replication, pathogenesis, and cytokine responses in syrian hamsters inoculated with SARS-CoV-2
Journal of Inflammation Research. 2021 Aug 11;14:3781-3795.
2021-07-12
A novel recombinant Fc gamma receptor-targeted survivin combines with chemotherapy for efficient cancer treatment
Biomedicines. 2021 Jul 12;9(7):Article number 806.
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