| 2021-01 |
Potent and orally active purine-based fetal hemoglobin inducers for treating Beta-thalassemia and sickle cell disease |
European Journal of Medicinal Chemistry. 2021 Jan;209:Article number 112938. |
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| 2020-08 |
Artificial intelligence approach fighting COVID-19 with repurposing drugs |
Biomedical Journal. 2020 Aug;43(4):355-362. |
|
| 2020-08 |
Repurposing old drugs as antiviral agents for coronaviruses |
Biomedical Journal. 2020 Aug;43(4):368-374. |
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| 2020-05 |
Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors |
Bioorganic Chemistry. 2020 May;98:Article number 103689. |
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| 2020-04 |
BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine |
Neuropharmacology. 2020 Apr;166:Article number 107678. |
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| 2020-02-18 |
Impacts of intralipid on nanodrug abraxane therapy and on the innate immune system |
Scientific Reports. 2020 Feb 18;10:Article number 2838. |
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| 2020-02-10 |
Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors |
Journal of Medicinal Chemistry. 2020 Feb 10;63(4):1642-1659. |
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| 2020-02-01 |
Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment |
European Journal of Medicinal Chemistry. 2020 Feb 1;187:Article number 111915. |
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| 2019-12 |
Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia |
Journal of Medicinal Chemistry. 2019 Dec;62(24):11135-11150. |
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| 2019-11-27 |
Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer |
Journal of Medicinal Chemistry. 2019 Nov 27;62(22):10108-10123. |
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| 2019-07-11 |
Linker optimization and therapeutic evaluation of phosphatidylserine-targeting zinc dipicolylamine-based drug conjugates |
Journal of Medicinal Chemistry. 2019 Jul 11;62(13):6047-6062. |
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| 2019-06-05 |
Delta-opioid receptor antagonist naltrindole reduces oxycodone addiction and constipation in mice |
European Journal of Pharmacology. 2019 Jun 5;852:265-273. |
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| 2019-05 |
Synthesis and evaluation of novel 7H-pyrrolo-[2,3-d]pyrimidine derivatives as potential anticancer agents |
Future Medicinal Chemistry. 2019 May;11(9):959-974. |
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| 2019-04-10 |
Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants |
Journal of Medicinal Chemistry. 2019 Apr 10;62(8):3940-3957. |
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| 2019-04-01 |
A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus |
European Journal of Medicinal Chemistry. 2019 Apr 1;167:245-268. |
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| 2019-03 |
Synthesis and biological evaluation of N-glucosyl indole derivatives as sodium-dependent glucose co-transporter 2 inhibitors |
Bioorganic Chemistry. 2019 Mar;83:520-525. |
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| 2018-08-23 |
5-aroylindoles act as selective histone deacetylase 6 inhibitors ameliorating alzheimer's disease phenotypes |
Journal of Medicinal Chemistry. 2018 Aug 23;61(16):7087-7102. |
|
| 2018-06-15 |
2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition [Erratum: Organic and Biomolecular Chemistry. 2016 Jan;14(2):716-723.] |
Organic and biomolecular chemistry. 2018 Jun 15;16:4734. |
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| 2018-04 |
4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy |
Bioorganic Chemistry. 2018 Apr;77:600-607. |
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| 2018-02-08 |
Development of stem-cell-mobilizing agents targeting CXCR4 receptor for peripheral blood stem cell transplantation and beyond |
Journal of Medicinal Chemistry. 2018 Feb 8;61(3):818-833. |
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| 2018-01-01 |
Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2 |
European Journal of Medicinal Chemistry. 2018 Jan 1;143:611-620. |
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| 2017-08-11 |
Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer |
Scientific Reports. 2017 Aug 11;7:Article number 7972. |
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| 2017-07 |
Design, synthesis, and evaluation of thiazolidine-2,4-dione derivatives as a novel class of glutaminase inhibitors |
Journal of Medicinal Chemistry. 2017 Jul;60(13):5599-5612. |
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| 2017-07 |
Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates |
Bioconjugate Chemistry. 2017 Jul;28(7):1878-1892. |
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| 2017-05 |
1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: A novel opioid receptor agonist with less accompanying gastrointestinal dysfunction than morphine |
Anesthesiology. 2017 May;126(5):952-966. |
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