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    日期題名關聯
    2024-11-08 Endosomes serve as signaling platforms for RIG-I ubiquitination and activation Science Advances. 2024 Nov 08;10(45):Article number eadq0660.
    2024-06-14 DUSP22 inhibits lung tumorigenesis by suppression of EGFR/c-Met signaling Cell Death Discovery. 2024 Jun 14;10:Article number 285.
    2024-06 UHRF1P contributes to IL-17A-mediated systemic lupus erythematosus via UHRF1-MAP4K3 axis Journal of Autoimmunity. 2024 Jun;146:Article number 103221.
    2024-03-27 Association of TRAIL receptor with phosphatase SHP-1 enables repressing T cell receptor signaling and T cell activation through inactivating Lck Journal of Biomedical Science. 2024 Mar 27;31:Article number 33.
    2024-01-15 The phosphatase DUSP22 inhibits UBR2-mediated K63-ubiquitination and activation of Lck downstream of TCR signalling Nature Communications. 2024 Jan 15;15:Article number 532.
    2023-12-05 Dual-specificity phosphatase 6 deficiency attenuates arterial-injury-induced intimal hyperplasia in mice International Journal of Molecular Sciences. 2023 Dec 05;24(24):Article number 17136.
    2023-11-01 DUSP8 induces TGF-beta–stimulated IL-9 transcription and Th9-mediated allergic inflammation by promoting nuclear export of Pur-Alpha Journal of Clinical Investigation. 2023 Nov 01;133(21):Article number e166269.
    2023-08-22 ACE2 in chronic disease and COVID-19: Gene regulation and post-translational modification Journal of Biomedical Science. 2023 Aug 22;30:Article number 71.
    2023-06 Hematopoietic progenitor kinase 1 inhibits the development and progression of pancreatic intraepithelial neoplasia Journal of Clinical Investigation. 2023 Jun 15;133(12):Article number e163873.
    2023-05-01 DUSP8 induces TGF-Beta-stimulated IL-9 transcription and Th9-mediated immune responses by inactivating a transcriptional repressor Journal of Immunology. 2023 May 01;210(Suppl. 1):Abstract number 243.04.
    2023-04-22 DUSP6 deficiency attenuates neurodegeneration after global cerebral ischemia International Journal of Molecular Sciences. 2023 Apr 22;24(9):Article number 7690.
    2023-02-10 Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis BMC Medicine. 2023 Feb 10;21:Article number 46.
    2022-07-27 SARS-CoV-2 spike protein enhances MAP4K3/GLK-induced ACE2 stability in COVID-19 EMBO Molecular Medicine. 2022 Jul 27:Article number e15904.
    2022-07-18 MAP4K3/GLK inhibits Treg differentiation by direct phosphorylating IKK beta and inducing IKK beta-mediated FoxO1 nuclear export and Foxp3 downregulation Theranostics. 2022 Jul 18;12(12):5744-5760.
    2022-06-15 DUSP3 regulates phosphorylation-mediated degradation of occludin and is required for maintaining epithelial tight junction Journal of Biomedical Science. 2022 Jun 15;29:Article number 40.
    2022-02-18 Single-cell RNA sequencing uncovers the individual alteration of intestinal mucosal immunocytes in Dusp6 knockout mice iScience. 2022 Feb 18;25(2):Article number 103738.
    2022-02 Genomic sequencing and functional analyses identify MAP4K3/GLK germline and somatic variants associated with systemic lupus erythematosus Annals of the Rheumatic Diseases. 2022 Feb;81(2):243-254.
    2022-01 Induction of interferon-gamma and tissue inflammation by overexpression of eosinophil cationic protein in T cells and exosomes Arthritis and Rheumatology. 2022 Jan;74(1):92-104.
    2021-11-23 Identification of a gut microbiota member that ameliorates DSS-induced colitis in intestinal barrier enhanced Dusp6-deficient mice Cell Reports. 2021 Nov 23;37(8):Article number 110016.
    2021-10-25 BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus Theranostics. 2021 Oct 25;11(20):9953-9966.
    2020-10-12 Structural insights into the active site formation of dusp22 in n-loop-containing protein tyrosine phosphatases International Journal of Molecular Sciences. 2020 Oct 12;21(20):Article number 7515.
    2020-08-12 DUSP11 attenuates lipopolysaccharide-induced macrophage activation by targeting TAK1 Journal of Immunology. 2020 Aug 12;205(6):1644-1652.
    2019-12 DUSP22 suppresses prostate cancer proliferation by targeting the EGFR-AR axis FASEB Journal. 2019 Dec 5;33(12):14653-14667.
    2019-11-13 MAP4K family kinases and DUSP family phosphatases in T-Cell signaling and systemic lupus erythematosus Cells. 2019 Nov 13;8(11):Article number 1433.
    2019-10-22 MAP4K3/GLK in autoimmune disease, cancer and aging Journal of Biomedical Science. 2019 Oct 22;26:Article number 82.
    2019-10 AhR-ROR-gammat complex is a therapeutic target for MAP4K3/GLK(high)IL-17A(high) subpopulation of systemic lupus erythematosus FASEB Journal. 2019 Oct;3(10):11469-11480.
    2019-10 MAP4K3/GLK promotes lung cancer metastasis by phosphorylating and activating IQGAP1 Cancer Research. 2019 Oct;79(19):4978-4993.
    2019-07 PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency Cell Death and Differentiation. 2019 Jul;26 (7):1221-1234.
    2019-05-30 Regulation of Dual-Specificity Phosphatase (DUSP) ubiquitination and protein stability International Journal of Molecular Sciences. 2019 May 30;20(11):Article number 2668.
    2019-05 MAP4K3/GLK-induced AhR-RORyt complex is a novel therapeutic target for GLIC(high)IL-17A(high) subpopulation of SLE patients Journal of Immunology. 2019 May;202(1, Suppl. S):Meeting Abstract 132.2.
    2019-05 T-cell signaling in Th17-mediated inflammation Journal of Immunology. 2019 May;202(1, Suppl. S):Meeting Abstract 124.7.
    2019-05 Control of mucosal barrier functions and gut microbiome homeostasis by DUSP6 in colitis Journal of Immunology. 2019 May;202(1, Suppl. S):Meeting Abstract 191.8.
    2019-04 MAP4K4 inhibition promotes survival of human stem cell-derived cardiomyocytes and reduces infarct size in vivo Cell Stem Cell. 2019 Apr;24(4):579-591.e12.
    2018-12 RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell Biochimica et Biophysica Acta-Molecular Cell Research. 2018 Feb;1865(2):259-272.
    2018-12 Induction of DUSP14 ubiquitination by PRMT5-mediated arginine methylation FASEB Journal. 2018 Dec;32(12):6760-6770.
    2018-12 Induction of TRAF2-mediated DUSP14/MKP6 ubiquitination by PRMT5-mediated arginine methylation Molecular Biology of the Cell. 2018 Dec;29(26):Abstract number P1574.
    2018-09-12 GLK-IKKbeta signaling induces dimerization and translocation of the AhR-RORgammat complex in IL-17A induction and autoimmune disease Science Advances. 2018 Sep 12;4(9):Article number eaat5401.
    2018-09-06 RBM4A-SRSF3-MAP4K4 splicing cascade constitutes a molecular mechanism for regulating brown adipogenesis International Journal of Molecular Sciences. 2018 Sep 6;19(9):Article number 2646.
    2018-08-21 DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation Proceedings of the National Academy of Sciences of the United States of America. 2018 Aug 21;115(34):E8027-E8036.
    2018 MAP4K3 (GLK) Encyclopedia of Signaling Molecules. 2018 :2947-2951.
    2017-11 Deficiency in VHR/DUSP3, a suppressor of focal adhesion kinase, reveals its role in regulating cell adhesion and migration Oncogene. 2017 Nov;36(47):6509-6517.
    2017-02 Dual-specificity phosphatase 6 deficiency regulates gut microbiome and transcriptome response against diet-induced obesity in mice Nature Microbiology. 2017 Feb;2(2):Article number 16220.
    2017-01-07 MAP4K4 and IL-6+ Th17 cells play important roles in non-obese type 2 diabetes Journal of Biomedical Science. 2017 Jan 7;24:Article number 4.
    2016-08 Downregulation of the phosphatase JKAP/DUSP22 in T Cells as a potential new biomarker of systemic lupus erythematosus nephritis Oncotarget. 2016 Aug;7(36):57593-57605.
    2016-08 Roles of innate immune regulator TAPE in RIG-I signaling and antiviral defenses European Journal of Immunology. 2016 Aug;46(Suppl. 1):569.
    2016-08 Emerging roles of an innate immune regulator TAPE in Toll-like receptors, RIG-I-like receptors, and beyond European Journal of Immunology. 2016 Aug;46(Suppl. 1):646.
    2016-08 Serine/threonine phosphatase PP4 is required for class switch recombination through recruitment of gammaH2AX European Journal of Immunology. 2016 Aug;46(Suppl. 1):62.
    2016-08 Molecular mechanisms of DUSP22 ablation in enhancing EGFR-mediated lung tumor development: Potential involvement of immunosuppression European Journal of Immunology. 2016 Aug;46(Suppl. 1):240.
    2016-08 HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to T-cell-mediated type 2 diabetes European Journal of Immunology. 2016 Aug;46(Suppl. 1):84-85.
    2016-07 GLK/MAP4K3 overexpression associates with recurrence risk for non-small cell lung cancer Oncotarget. 2016 Jul;7(27):41748-41757.

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