國家衛生研究院 NHRI:Item 3990099045/4846

NHRI > Institute of Biomedical Engineering and Nanomedicine > Others > Conference Papers/Meeting Abstract > Item 3990099045/4846

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/4846

Title:	A novel approach to identify the thermal mechanism in high- and low- frequency focused ultrasound thermal ablation process
Other Titles:	6th International Symposium on Therapeutic Ultrasound
Authors:	Liu, H;Chen, Y;Chen, W;Shih, T;Chen, J;Lin, W
Contributors:	Division of Medical Engineering Research
Abstract:	The purpose of this study is to propose a novel approach to identify the thermal mechanism during the high- and low- frequency focused ultrasound thermal ablation process, and to verify that the occurrence of the ultrasound-induced macroscopically visible bubbles exert another key effect in thermal lesion formation during the focused ultrasound thermal ablation process. In our experiments, consecutive sonications with orthogonal intersections were applied to observe the thermal lesion interaction induced by 577- or 1155-kHz ultrasound. Results showed that the 1155-kHz heating was dominated by ultrasound energy absorption, with blocking of consecutive sonications being evident only rarely. However, in 577-kHz sonications, the thermal process was dominated by inertial cavitation and the corresponding ultrasound-induced macroscopic visible bubbles, which was verified form the later lesion been blocked by the former one and direct observation from light microscopy. This study demonstrates that the operating frequency for ultrasound thermal ablation should be selected based on the intended specific thermal mechanisms to be induced.
Date:	2007-05
Relation:	6th International Symposium on Therapeutic Ultrasound. 2007 May;911:144-149.
Link to:	http://dx.doi.org/10.1063/1.2744265
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000247342200023
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=34548707895
Appears in Collections:	[Others] Conference Papers/Meeting Abstract

Files in This Item:

File	Description	Size	Format
SCP34548707895.pdf		875Kb	Adobe PDF	751	View/Open

Loading...