國家衛生研究院 NHRI:
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    近3年内发表的文件:6(10.91%)
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    日期题名關聯
    2024-09-18 Crosstalk between FTH1 and PYCR1 dysregulates proline metabolism and mediates cell growth in KRAS-mutant pancreatic cancer cells Experimental and Molecular Medicine. 2024 Sep 18;56:2065-2081.
    2024-07-04 Development of a humanized antibody targeting extracellular HSP90alpha to suppress endothelial-mesenchymal transition-enhanced tumor growth of pancreatic adenocarcinoma cells Cells. 2024 Jul 04;13(13):Article number 1146.
    2024-03-15 Epstein-barr virus BRLF1 induces PD-L1 expression in nasopharyngeal carcinoma cells Viral Immunology. 2024 Mar 15;37(2):115-123.
    2023-07-13 Screening and identification of emodin as an EBV DNase inhibitor to prevent its biological functions Virology Journal. 2023 Jul 13;20:Article number 148.
    2023-06-12 Kruppel-like factor 10 modulates stem cell phenotypes of pancreatic adenocarcinoma by transcriptionally regulating notch receptors Journal of Biomedical Science. 2023 Jun 12;30:Article number 39.
    2022-01-11 Extracellular HSP90alpha induces MyD88-IRAK complex-associated IKKalpha/Beta−NF-KappaB/IRF3 and JAK2/TYK2−STAT-3 signaling in macrophages for tumor-promoting M2-polarization Cells. 2022 Jan 11;11(2):Article number 229.
    2020-01 Octyl gallate induces pancreatic ductal adenocarcinoma cell apoptosis and suppresses endothelial-mesenchymal transition-promoted M2-Macrophages, HSP90alpha secretion, and tumor growth Cells. 2020 Jan;9(1):Article number 91.
    2019-12-17 Endothelial-mesenchymal transition harnesses HSP90alpha-secreting M2-macrophages to exacerbate pancreatic ductal adenocarcinoma Journal of Hematology and Oncology. 2019 Dec 17;12:Article number 138.
    2018-12-22 Osteopontin-integrin engagement induces HIF-1α-TCF12- mediated endothelial-mesenchymal transition to exacerbate colorectal cancer Oncotarget. 2018 Dec 22;9(4):4998-5015.
    2018-02-01 Myeloid-derived macrophages and secreted HSP90alpha induce pancreatic ductal adenocarcinoma development OncoImmunology. 2018 Feb 1;7(5):Article number e1424612.
    2016-05 Bone marrow derived macrophages fuse with intestine stromal cells and contribute to chronic fibrosis after radiation Radiotherapy and Oncology. 2016 May;119(2):250-258.
    2014-07 Oestrogen-induced angiogenesis promotes adenomyosis by activating the Slug-VEGF axis in endometrial epithelial cells Journal of Cellular and Molecular Medicine. 2014 Jul;18(7):1358-1371.
    2014-04 The endothelin-integrin axis is involved in macrophage-induced breast cancer cell chemotactic interactions with endothelial cells Journal of Biological Chemistry. 2014 Apr;289(14):10029-10044.
    2013-09 Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents Cancer Letters. 2013 Sep;337(2):218-225.
    2013-07-19 Surface alpha-enolase promotes extracellular matrix degradation and tumor metastasis and represents a new therapeutic target PLoS ONE. 2013 Jul 19;8(7):Article number e69354.
    2013-03-29 Secreted heat shock protein 90alpha (HSP90alpha) induces nuclear factor-kappaB-mediated TCF12 protein expression to down-regulate E-cadherin and to enhance colorectal cancer cell migration and invasion Journal of Biological Chemistry. 2013 Mar 29;288(13):9001-9010.
    2012-01-20 TCF12 protein functions as transcriptional repressor of E-cadherin, and its overexpression is correlated with metastasis of colorectal cancer Journal of Biological Chemistry. 2012 Jan 20;287(4):2798-2809.
    2011-08 Identification of heat shock protein 90alpha as an IMH-2 epitope-associated protein and correlation of its mRNA overexpression with colorectal cancer metastasis and poor prognosis International Journal of Colorectal Disease. 2011 Aug;26(8):1009-1017.
    2011-06 Sesamin inhibits macrophage-induced vascular endothelial growth factor and matrix metalloproteinase-9 expression and proangiogenic activity in breast cancer cells Inflammation. 2011 Jun;34(3):209-221.
    2011-02 Modulation of the development of human monocyte-derived dendritic cells by lithium chloride Journal of Cellular Physiology. 2010 Feb;226(2):424-433.
    2010-08 Secreted heat shock protein 90alpha induces colorectal cancer cell invasion through CD91/LRP-1 and NF-kappaB-mediated integrin alpha(V) expression Journal of Biological Chemistry. 2010 Aug;285(33):25458-25466.
    2010-04 Biochemical characterization of an acid phosphatase from thermus thermophilus Bioscience Biotechnology and Biochemistry. 2010 Apr;74(4):727-735.
    2007 Induction of FADD expression and caspase cascades involved in RC-RNase-induced apoptosis in human cervival cancer cells Journal of Cancer Molecules. 2007;3(3):81-89.
    2006-08 Tumor necrosis factor-alpha, Interleukin-8 and Interleukin-6 are involved in vascular endothelial cell capillary tube and network formation induced by tumor-associated macrophages Journal of Cancer Molecules. 2006 Aug;2(4):155-160.
    2006-08 Tumor-associated macrophage: Its role in tumor angiogenesis Journal of Cancer Molecules. 2006 Aug;2(4):135-140.
    2006 Sesamin inhibits vascular endothelial cell growth and angiogenic activity of lung adenocarcinoma cells Journal of Cancer Molecules. 2006;2(5):199-205.
    2005-12-15 Tumor beta-1,4-galactosyltransferase IV overexpression is closely associated with colorectal cancer metastasis and poor prognosis Clinical Cancer Research. 2005 Dec;11(24 Pt. 1):8615-8622.
    2005-09 Novel rapid tissue lysis method to evaluate cancer proteins: Correlation between elevated Bcl-XL expression and colorectal cancer cell proliferation World Journal of Gastroenterology. 2005 Sep;11(33):5162-5168.
    2005 Plasminogen activator inhibitor-1: the expression, biological function, and effects on tumorigenesis and tumor cell adhesion and migration Journal of Cancer Molecules. 2005;1(1):25-36.
    2005 Prognostic significance of elevated cyclin B1 expression in colorectal cancer: A rapid tissue lysis and immunoblot study Journal of Cancer Molecules. 2005;1(1):47-51.
    2004-11 Elevated level of spindle checkprotein MAD2 correlates with cellular mitotic arrest, but not with aneuploidy and clinicopathological characteristics in gastric cancer World Journal of Gastroenterology. 2004 Nov;10(22):3240-3244.
    2004-09 Advantages of assaying telomerase activity in ascites for diagnosis of digestive tract malignancies World Journal of Gastroenterology. 2004 Sep;10(17):2468-2471.
    2004-01 A G-quadruplex ligand 3,3 '-diethyloxadicarbocyanine iodide induces mitochondrion-mediated apoptosis but not decrease of telomerase activity in nasopharyngeal carcinoma NPC-TW01 cells Pharmaceutical Research. 2004 Jan;21(1):93-100.
    2003-01-24 Shortening of microsatellite deoxy(CA) repeats involved in GL331-induced down-regulation of matrix metalloproteinase-9 gene expression Biochemical and Biophysical Research Communications. 2003 Jan;300(4):901-907.
    2002-04 Detecting cytokeratin 19 mRNA in the peripheral blood cells of cervical cancer patients and its clinical-pathological correlation Gynecologic Oncology. 2002 Apr;85(1):148-153.
    2001-10 GL331 induces down-regulation of cyclin D1 expression via enhanced proteolysis and repressed transcription Molecular Pharmacology. 2001 Oct;60(4):768-775.
    2001-06 A novel topoisomerase II poison GL331 preferentially induces DNA cleavage at (C/G)T sites and can cause telomere DNA damage Pharmaceutical Research. 2001 Jun;18(6):846-851.
    2001-03 Evaluation of GL331 in combination with paclitaxel: GL331's interference with paclitaxel-induced cell cycle perturbation and apoptosis Anti-Cancer Drugs. 2001 Mar;12(3):259-266.
    2000-06 Activation of MAD 2 checkprotein and persistence of cyclin B1/CDC 2 activity associate with paclitaxel-induced apoptosis in human nasopharyngeal carcinoma cells Apoptosis. 2000 Jun;5(3):235-241.
    2000-02 In vitro evaluation of GL331's cancer cell killing and apoptosis-inducing activity in combination with other chemotherapeutic agents Apoptosis. 2000 Feb;5(1):79-85.
    1999-09 Analysis of astrocytoma heterogeneity: Detection of telomere shortening, BCL-2 expression, and multiple gains and losses of genetIc material in four primary cultures of astrocytoma Journal of Genetics and Molecular Biology. 1999 Sep;10(3):102-109.
    1999-07 A novel podophyllotoxin-derived compound GL331 is more potent than its congener VP-16 in killing refractory cancer cells Pharmaceutical Research. 1999 Jul;16(7):997-1002.
    1999-05-03 Inhibition of DNA synthesis by downregulation of cyclin A but not Skp 2 overexpression in human hepatocellular carcinoma cells Cancer Letters. 1999 May;139(1):1-6.
    1998-10-29 Bcl-2 prevents topoisomerase II inhibitor GL331-induced apoptosis is mediated by down-regulation of poly(ADP-ribose)polymerase activity Oncogene. 1998 Oct;17(17):2225-2234.
    1998-06 Elevated cytokeratin-19 expression associated with apoptotic resistance and malignant progression of human cervical carcinoma Apoptosis. 1998 Jun;3(3):161-169.
    1998-06 Differential inducibilities of GFAP expression, cytostasis and apoptosis in primary cultures of human astrocytic tumours Apoptosis. 1998 Jun;3(3):171-182.
    1998-03-01 Overexpression of cyclin A but not Skp 2 correlates with the tumor relapse of human hepatocellular carcinoma Cancer Research. 1998 Mar;58(5):985-990.
    1998-01 Taxol-induced p34(cdc2) kinase activation and apoptosis inhibited by 12-O-tetradecanoylphorbol-13-acetate in human breast MCF-7 carcinoma cells Cell Growth and Differentiation. 1998 Jan;9(1):23-29.
    1997-10 Cell cycle G(2)/M arrest and activation of cyclin-dependent kinases associated with low-dose paclitaxel-induced sub-G(1) apoptosis Apoptosis. 1997 Oct;2(5):463-470.
    1997-07-15 Activation of CDC 25 phosphatase and CDC 2 kinase involved in GL331-induced apoptosis Cancer Research. 1997 Jul;57(14):2974-2978.

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