國家衛生研究院 NHRI:
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    日期題名關聯
    2016-12 Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation Oncotarget. 2016 Dec;7(52):86239-86256.
    2016-12 Novel cKIT kinase inhibitor, BPRCKJ001, as an advanced therapeutic candidate for GIST Annals of Oncology. 2016 Dec;27(Suppl. 9):Meeting Abstract 2P.
    2016-10 BPR1J373, an oral multiple tyrosine kinase inhibitor, targets c-KIT for the treatment of c-KIT driven myeloid leukemia Molecular Cancer Therapeutics. 2016 Oct;15(10):2323-2333.
    2016-10 Multifunctional nanoparticles for oral protein drug delivery Diabetes Research and Clinical Practice. 2016 Oct;120(Suppl. 1):S19.
    2016-08 Dipeptidyl peptidase-4 inhibitor LAF-237 improves glucose tolerance and expends graft beta cell mass in diabetic mice transplanted with a sufficient number of islets Diabetologia. 2016 Aug;59(Suppl. 1):S198.
    2016-05 N-Indolylglycosides bearing modifications at the glucose C6-Position as Sodium-Dependent Glucose Co-transporter 2 inhibitors Bioorganic and Medicinal Chemistry. 2016 May;24(10):2242-2250.
    2016-02 Multifunctional nanoparticles for oral protein drug delivery Nanomedicine: Nanotechnology, Biology and Medicine. 2016 Feb;12(2):463.
    2015-09 Self-assembling bubble carriers for oral protein delivery Biomaterials. 2015 Sep;64:115-124.
    2015-08 Novel Nrf2/ARE activator, trans-coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38alpha/MAPKAPK-2 and PK-N3 signaling pathway Chemical Research in Toxicology. 2015 Aug ;28(9):1681-1692.
    2015-08 Zinc-dipicolylamine directed pharmaceutical delivery system (ZAPS) as an innovative cancer drug delivery platform Cancer Research. 2015 Aug;75(Suppl. 15):Abstract number 4413.
    2015-08 Optimization of quinazoline-based kinase inhibitors: Identification of a dual FLT3/AURKA kinase inhibitor for the treatment of acute myeloid leukemia Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 490.
    2015-07 Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations European Journal of Medicinal Chemistry. 2015 Jul;100:151-161.
    2015-04 IL-1beta promotes malignant transformation and tumor aggressiveness in oral cancer Journal of Cellular Physiology. 2015 APR;230(4):875-884.
    2015-03 Stem cell mobilizers targeting chemokine receptor CXCR4: Renoprotective application in acute kidney injury Journal of Medicinal Chemistry. 2015 Mar;58(5):2315-2325.
    2014-11 Discovery of multiple kinases inhibitors, DBPR114, as the novel anti-cancer agent European Journal of Cancer. 2014 Nov;50(Suppl. 6):92-93.
    2014-10 YYEI motif is critical to oncogenicity of 14-3-3 proteins Cancer Research. 2014 Oct;74(19 Suppl.):Abstract No. 3527.
    2014-10 Novel irreversible EGFR tyrosine kinase inhibitor, DBPR112, as a therapeutic candidate for lung adenocarcinoma Cancer Research. 2014 Oct;74(19 Suppl.):Abstract No. 1756.
    2014-08-15 Anticancer oral formulation 特許第5596680號/2014-08-15
    2014-08-04 Effects of dipeptidyl peptidase-4 inhibition with MK-0431 on syngeneic mouse islet transplantation International Journal of Endocrinology. 2014 Aug 4;2014:Article ID 795283.
    2014-06-04 抗癌口服制剂 ZL200980126979.4/2014-06-04
    2014-04 Treatment of chemotherapy-induced neutropenia in a rat model by using multiple daily doses of oral administration of G-CSF-containing nanoparticles Biomaterials. 2014 Apr;35(11):3641-3649.
    2014-03 DBPR112, a potent and selective EGFR kinase inhibitor in preclinical study Abstracts of Papers - American Chemical Society. 2014 Mar;247:Article number 315-MEDI.
    2014-01-08 Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer PLoS ONE. 2014 Jan 8;9(1):Article number e83160.
    2013-11 BPR0C305, an orally active microtubule-disrupting anticancer agent Anticancer Drugs. 2013 Nov;24(10):1047-1057.
    2013-11 A development drug candidate targeting EGFR kinase for lung cancer: DBPR112 Journal of Thoracic Oncology. 2013 Nov;8(Suppl. 2):S779-S780.

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