國家衛生研究院 NHRI:
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    显示项目26-50 / 212. (共9页)
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    日期题名關聯
    2021-08 A noninvasive gut-to-brain oral drug delivery system for treating brain tumors Advanced Materials. 2021 Aug;33(34):Article number e2100701.
    2021-05-19 Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins Journal of Medicinal Chemistry. 2021 May 19;64(11):7312-7330.
    2021-01 BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy Translational Oncology. 2021 Jan;14(1):Article number 100897.
    2021-01 Potent and orally active purine-based fetal hemoglobin inducers for treating Beta-thalassemia and sickle cell disease European Journal of Medicinal Chemistry. 2021 Jan;209:Article number 112938.
    2020-12-14 Inhibition of SARS-CoV-2 by highly potent broad-spectrum anti-coronaviral tylophorine-based derivatives Frontiers in Pharmacology. 2020 Dec 14;11:Article number 606097.
    2020-11 Molecular profiling of afatinib-resistant non-small cell lung cancer cells in vivo derived from mice Pharmacological Research. 2020 Nov;161:Article number 105183.
    2020-10-08 Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery Scientific Reports. 2020 Oct 8;10:Article number 16771.
    2020-10 A bubble bursting-mediated oral drug delivery system that enables concurrent delivery of lipophilic and hydrophilic chemotherapeutics for treating pancreatic tumors in rats Biomaterials. 2020 Oct;255:Article number 120157.
    2020-08-20 Discovery of M protease inhibitors encoded by SARS-CoV-2 Antimicrobial Agents and Chemotherapy. 2020 Aug 20;64(9):e00872-20.
    2020-08 Artificial intelligence approach fighting COVID-19 with repurposing drugs Biomedical Journal. 2020 Aug;43(4):355-362.
    2020-08 Repurposing old drugs as antiviral agents for coronaviruses Biomedical Journal. 2020 Aug;43(4):368-374.
    2020-08 BPR6K609: An Aurora kinase inhibitor targeting small cell lung cancer with MYC amplification Cancer Research. 2020 Aug;80(16):1937.
    2020-02-18 Impacts of intralipid on nanodrug abraxane therapy and on the innate immune system Scientific Reports. 2020 Feb 18;10:Article number 2838.
    2019-12 A novel flavivirus entry inhibitor, BP34610, discovered through high-throughput screening with dengue reporter viruses Antiviral Research. 2019 Dec;172:Article number 104636.
    2019-12 Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia Journal of Medicinal Chemistry. 2019 Dec;62(24):11135-11150.
    2019-11-27 Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer Journal of Medicinal Chemistry. 2019 Nov 27;62(22):10108-10123.
    2019-10 Inhibition of Rspo-Wnt pathway facilitates checkpoint blockade therapy by anti-RSPO3 antibody (DBPR117) Annals of Oncology. 2019 Oct;30(Suppl. 5):191.
    2019-09 Effects of boschnaloside from Boschniakia rossica on dysglycemia and islet dysfunction in severely diabetic mice through modulating the action of glucagon-like peptide-1 Phytomedicine. 2019 Sep;62:Article number 152946.
    2019-08-27 A dengue virus type 2 (DENV-2) NS4B-interacting host factor, SERP1, reduces DENV-2 production by suppressing viral RNA replication Viruses. 2019 Aug 27;11(9):Article number 787.
    2019-07-11 Linker optimization and therapeutic evaluation of phosphatidylserine-targeting zinc dipicolylamine-based drug conjugates Journal of Medicinal Chemistry. 2019 Jul 11;62(13):6047-6062.
    2019-07 Citronellol induces necroptosis of human lung cancer cells via TNF-alpha pathway and reactive oxygen species accumulation In Vivo. 2019 Jul-Aug;33(4):1193-1201.
    2019-07 Use of integrated genomic analyses in patient-derived tumor model to discover new clinical indications for the multikinase inhibitor drug candidate, DBPR216 Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 4626.
    2019-07 BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 227.
    2019-07 An Aurora kinase inhibitor BPR6K471 inhibits tumor growth and reduces the cancer stem cell-like properties of small cell lung cancer Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 3851.
    2019-06-15 Strategies for improving diabetic therapy via alternative administration routes that involve stimuli-responsive insulin-delivering systems Advanced Drug Delivery Reviews. 2019 Jan 15;139(SI):71-82.

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