國家衛生研究院 NHRI:
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    显示项目51-75 / 212. (共9页)
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    日期题名關聯
    2013-11-21 治療癌症的醫藥組成物 I415852/2013-11-21
    2013-11-13 Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice Journal of Medicinal Chemistry. 2013 Nov 13;56(24):9920-9933.
    2013-11 BPR0C305, an orally active microtubule-disrupting anticancer agent Anticancer Drugs. 2013 Nov;24(10):1047-1057.
    2013-10-01 喹啉化合物及包含其之治療病毒感染之醫藥組成物 I410245/2013-10-01
    2013-09-27 Pyrrolidine derivatives RU2494094C2/2013-09-27
    2013-09-11 噻吩化合物及其醫藥組成物 I408136/2013-09-11
    2013-08-21 Fused multicyclic compounds as protein kinase inhibitors EP2331530B1/2013-08-21
    2013-08-13 Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors US8507502B2/2013-08-13
    2013-07-16 Dibenzo[f,h]isoquinoline derivatives US8486959B2/2013-07-16
    2013-07-01 做為蛋白質激酶抑制劑之稠合多環化合物 I400242/2013-07-01
    2013-06-28 Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor Journal of Medicinal Chemistry. 2013 Jun 28;56(13):5247-5260.
    2013-06-05 Anticancer oral formulation EP2310363B1/2013-06-05
    2013-06 c-Jun-mediated anti-cancer mechanisms of tylophorine Carcinogenesis. 2013 Jun;34(6):1304-1314.
    2013-06 Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) Bioorganic and Medicinal Chemistry. 2013 Jun;21(11):2856-2867.
    2013-05 Characterization of an efficient dengue virus replicon for development of assays of discovery of small molecules against dengue virus Antiviral Research. 2013 May;98(2):228-241.
    2013-05 Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules Proceedings of the National Academy of Sciences of the United States of America. 2013 May;110(19):E1779-E1787.
    2013-05 Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors Journal of Medicinal Chemistry. 2013 May;56(10):3889-3903.
    2013-04-30 Pyrrolidine derivatives 164613/2013-04-30
    2013-04-13 Exploration of the role of tylophorine E ring in anti-Coronavirus activity-Tylophorine derived dibenzoquinolines impart multi-biological activities as orally active agents FASEB Journal. 2013 Apr 13;27:lb71.
    2013-04-09 Proline derivatives US8415482B2/2013-04-09
    2013-04-07 BPR000K, a novel Aurora kinase inhibitor Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 300-MEDI.
    2013-04-07 3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 87-MEDI.
    2013-04-07 Development drug candidate targeting EGFR kinase: DBPR112 Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 299-MEDI.
    2013-04 Tylophorine induces c-Jun protein accumulation through two discrete prolonged pathways NF-kappaB/PKCdelta/JNK and PI3K/PDK1/PP2A/eEF2 to promote G1 arrest in carcinoma cells FASEB Journal. 2013 Apr;27:lb74.
    2013-04 Identification of a quinone compound inhibits human glutaminase activity and induces autophagy in carcinoma cells FASEB Journal. 2013 Apr;27:lb70.

    显示项目51-75 / 212. (共9页)
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