國家衛生研究院 NHRI:
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    Conference Papers/Meeting Abstract [10/19]

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    Showing items 126-150 of 212. (9 Page(s) Totally)
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    DateTitleRelation
    2011-03-27 Design and synthesis of potent Aurora kinase inhibitors Abstracts of Papers - American Chemical Society. 2011 Mar 27;241:258-MEDI.
    2011-03-21 吡唑化合物及其醫藥組成物 I339205/2011-03-21
    2011-03-01 Thiourea derivatives US7897764B2/2011-03-01
    2011-03 Successful propagation of flavivirus infectious cDNAs by a novel method to reduce the cryptic bacterial promoter activity of virus genomes Journal of Virology. 2011 Mar;85(6):2927-2941.
    2011-02 Synthesis of 3,3-dimethylglutamic acid derivatives as DPP-IV inhibitors and evaluation of their chemical stability Journal of the Chinese Chemical Society. 2011 Feb;58(1):108-117.
    2011-01-13 Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes Journal of Medicinal Chemistry. 2011 Jan 13;54(1):166-178.
    2011-01 Novel dengue virus-specific NS2B/NS3 protease inhibitor, BP2109, discovered by a high-throughput screening assay Antimicrobial Agents and Chemotherapy. 2011 Jan;55(1):229-238.
    2011-01 BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities Cancer Science. 2011 Jan;102(1):182-191.
    2010-12-01 吲哚化合物 ZL200480034988.8/2010-12-01
    2010-12-01 抗肿瘤化合物 ZL200580045509.7/2010-12-01
    2010-12 Discovery of non-glycoside sodium-dependent glucose Co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening Journal of Medicinal Chemistry. 2010 Dec;53(24):8770-8774.
    2010-11-16 Thiophene compounds US7834046B2/2010-11-16
    2010-11 Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus Antiviral Research. 2010 Nov;88(2):160-168.
    2010-10-28 Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency Journal of Medicinal Chemistry. 2010 Oct 28;53(20):7316-7326.
    2010-10-06 吡咯烷化合物 ZL200580009891.6/2010-10-06
    2010-10 Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities Pharmacological Research. 2010 Oct;62(4):337-343.
    2010-10 Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists ChemMedChem. 2010 Oct;5(10):1707-1716.
    2010-09-28 Selenophene compounds US7803799B2/2010-09-28
    2010-09-01 Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors Bioorganic and Medicinal Chemistry. 2010 Sep ;18(17):6414-6421.
    2010-09 Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophe n-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist ChemMedChem. 2010 Sep;5(9):1439-1443.
    2010-08-21 硫尿化合物及抑制C型肝炎病毒感染之方法 I329102/2010-08-21
    2010-08 Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein Journal of Medicinal Chemistry. 2010 Aug;53(18):6572-6583.
    2010-08 Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models Abstracts of Papers - American Chemical Society. 2010 Aug;240:MEDI 332.
    2010-07 Antiangiogenic Activities and Cisplatin-combined Antitumor Activities of BPR0L075 Anticancer Research. 2010 Jul;30(7):2813-2822.
    2010-06-15 (2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV Bioorganic and Medicinal Chemistry Letters. 2010 Jun 15;20(12):3596-3600.

    Showing items 126-150 of 212. (9 Page(s) Totally)
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