| 2013-09 |
MPT0B098, a novel microtubule inhibitor that destabilizes the hypoxia-inducible factor-1α mrna through decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR [Erratum: Molecular Cancer Therapeutics. 2013 Jul;12(7):1202-1212.] |
Molecular Cancer Therapeutics. 2013 Sep;12(9):1919. |
 |
| 2013-09 |
Furanylazaindoles: Potent anticancer agents in vitro and in vivo |
Journal of Medicinal Chemistry. 2013 Sep;56(20):8008-8018. |
|
| 2013-07-15 |
Microtubule-associated histone deacetylase 6 supports the calcium store sensor STIM1 in mediating malignant cell behaviors |
Cancer Research. 2013 Jul 15;73(14):4500-4509. |
|
| 2013-07 |
Epigenetic regulation of the X-linked tumour suppressors BEX1 and LDOC1 in oral squamous cell carcinoma |
Journal of Pathology. 2013 Jul;230(3):298-309. |
|
| 2013-07 |
MPT0B098, a novel microtubule inhibitor that destabilizes the hypoxia-inducible factor-1 alpha mRNA through decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR |
Molecular Cancer Therapeutics. 2013 Jul;12(7):1202-1212. |
|
| 2013-06-27 |
Dissecting the EGFR-PI3K-AKT pathway in oral cancer highlights the role of the EGFR variant III and its clinical relevance |
Journal of Biomedical Science. 2013 Jun 27;20(1):Article number 43. |
|
| 2013-06-13 |
Cholestane-3beta, 5alpha, 6beta-triol suppresses proliferation, migration, and invasion of human prostate cancer cells |
PLoS ONE. 2013 Jun 13;8(6):Article number e65734. |
|
| 2013-06 |
Oral hygiene and risk of head and neck cancer |
American Journal of Epidemiology. 2013 Jun;177(Suppl. 11):S58. |
|
| 2013-05 |
Activation of PPAR-alpha induces cell cycle arrest and inhibits transforming growth factor-beta1 induction of smooth muscle cell phenotype in 10T1/2 mesenchymal cells |
Cellular Signalling. 2013 May;25(5):1252-1263. |
|
| 2013-04-24 |
Caffeic acid phenethyl ester suppresses proliferation and survival of TW2.6 human oral cancer cells via inhibition of Akt signaling |
International Journal of Molecular Sciences. 2013 Apr 24;14(5):8801-8817. |
|
| 2013-04 |
Functional implication of TGFBR3 dysregulation and its clinical application in oral cancer |
Cancer Research. 2013 Apr;73(8 Suppl. 1):Abstract number 3987. |
|
| 2013-04 |
Generation and characterization of highly selective cathepsin S inhibitors with potentials against pancreatic cancer |
Cancer Research. 2013 Apr;73(8 Suppl. 1):Abstract number 5562. |
|
| 2013-04 |
EGFR variant III act as the major determinant factors in the EGFR/PI3K/AKT pathway for the survival outcome of oral cancer patients |
Cancer Research. 2013 Apr;73(8 Suppl. 1):Abstract number 2390. |
|
| 2013-04 |
Autophagy induced by cathepsin S inhibition causes early ROS production for oxidative DNA damage and subsequent cell death |
Cancer Research. 2013 Apr;73(8 Suppl. 1):Abstract number 1661. |
|
| 2013-03-12 |
A novel synthetic microtubule inhibitor, MPT0B214 exhibits antitumor activity in human tumor cells through mitochondria-dependent intrinsic pathway |
PLoS ONE. 2013 Mar 12;8(3):Article number e58953. |
|
| 2013-02-01 |
Allergies and risk of head and neck cancer: An original study plus meta-analysis |
PLoS ONE. 2013 Feb 1;8(2):Article number e55138. |
|
| 2013-01 |
Randomised clinical trial: Comparison of two everolimus dosing schedules in patients with advanced hepatocellular carcinoma |
Alimentary Pharmacology and Therapeutics. 2013 Jan;37(1):62-73. |
|
| 2012-12 |
Arginine deprivation as a new treatment strategy for head and neck cancer |
Oral Oncology. 2012 Dec;48(12):1227-1235. |
|
| 2012-12 |
Application of Suzuki arylation, Sonogashira ethynylation and Rosenmund-von Braun cyanation in the exploration of substitution effects on the anticancer activity of 2-aroylquinolines |
Organic and Biomolecular Chemistry. 2012 Dec;10(48):9593-9600. |
|
| 2012-11 |
Overexpression of Discoidin Domain Receptor 1 (DDR1) in oral squamous cell carcinoma |
European Journal of Cancer. 2012 Nov;48(Suppl. 6):167. |
|
| 2012-11 |
Blockage of Nrf2/AKR1C axis enhanced therapeutic efficacy of oxaliplatin in oxaliplatin resistant gastric cancer cells |
European Journal of Cancer. 2012 Nov;48(Suppl. 6):48. |
|
| 2012-11 |
MicroRNA-99a, a tumor suppressor in oral squamous cell carcinoma regulates insulin-like growth factors I receptor in a double-negative feedback loop |
European Journal of Cancer. 2012 Nov;48(Suppl. 6):120. |
|
| 2012-06-15 |
Targeted Casp8AP2 methylation increases drug resistance in mesenchymal stem cells and cancer cells |
Biochemical and Biophysical Research Communications. 2012 Jun 15;422(4):578-585. |
|
| 2012-04 |
Targeting cathepsin S induces tumor cell autophagy via the EGFR-Erk signaling pathway |
Cancer Letters. 2012 Apr;317(1):89-98. |
|
| 2012-04 |
DNA polymerase eta and a novel anticancer selenophene compound |
Cancer Research. 2012 Apr;72:Abstract number 3813. |
|
| 2012-03-06 |
Indole compounds |
CA2437104/2012-03-06 |
|
| 2012-03 |
Modulation of chemotactic and pro-inflammatory activities of endothelial progenitor cells by hepatocellular carcinoma |
Cellular Signalling. 2012 Mar;24(3):779-793. |
|
| 2012-02 |
Phase I study of biweekly liposome irinotecan (PEP02, MM-398) in metastatic colorectal cancer failed on firstline oxaliplatin-based chemotherapy |
Journal of Clinical Oncology. 2012 Feb;30(4):613. |
|
| 2012-01 |
Differences in the frequencies of K-ras c12-13 genotypes by gender and pathologic phenotypes in colorectal tumors measured using the allele discrimination method |
Environmental and Molecular Mutagenesis. 2012 Jan;53(1):22-31. |
|
| 2011-12-22 |
5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2 |
Journal of Medicinal Chemistry. 2011 Dec 22;54(24):8517-8525. |
|
| 2011-12-15 |
Combination of arsenic trioxide and BCNU synergistically triggers redox-mediated autophagic cell death in human solid tumors |
Free Radical Biology and Medicine. 2011 Dec 15;51(12):2195-2209. |
|
| 2011-12 |
Induction chemotherapy with gemcitabine, oxaliplatin, and 5-Fluorouracil/Leucovorin followed by concomitant chemoradiotherapy in patients with locally advanced pancreatic cancer: A Taiwan cooperative oncology group phase II study |
International Journal of Radiation Oncology, Biology, Physics. 2011 Dec;81(5):e749-e757. |
|
| 2011-11-15 |
Novel phosphoinositide 3-kinase/mTOR dual inhibitor, NVP-BGT226, displays potent growth-inhibitory activity against human head and neck cancer cells in vitro and in vivo |
Clinical Cancer Research. 2011 Nov 15;17(22):7116-7126. |
|
| 2011-11-15 |
Coumarin compounds and their use for treating cancer |
US8058427B2/2011-11-15 |
|
| 2011-10-01 |
Enhancement of non-homologous end joining DNA repair capacity confers cancer cells resistance to the novel selenophene compound, D-501036 |
Cancer Letters. 2011 Oct 1;309(1):110-118. |
|
| 2011-10 |
Novel terpenoids from calocedrus macrolepis var. formosana |
Chemistry and Biodiversity. 2011 Oct;8(10):1901-1907. |
|
| 2011-09-23 |
BPR1K653, a novel Aurora Kinase Inhibitor, exhibits potent anti-proliferative activity in P-gp170 (MDR1)-mediated VX680-resistant cancer cells in vitro and in vivo |
European Journal of Cancer. 2011 Sep 23;47:S127. |
|
| 2011-09-23 |
A phase II study of neoadjuvant bio-chemotherapy with Cetuximab, Paclitaxel, and Cisplatin (CPC) followed by Cetuximab-based concurrent bio-radiotherapy in high-risk locally advanced head and neck cancer - representative of head and neck cancer study grou |
European Journal of Cancer. 2011 Sep 23;47:S547-S548. |
|
| 2011-09 |
Synthesis and biological evaluation of 1-(4′-Indolyl and 6′-Quinolinyl) indoles as a new class of potent anticancer agents |
European Journal of Medicinal Chemistry. 2011 Sep;46(9):3623-3629. |
|
| 2011-09 |
DNA repair enzyme, O6-methylguanine DNa methyltransferase, modulates therapeutic efficacy of platinum drugs with radiation and its clinical significance |
European Journal of Cancer. 2011 Sep;47:S132. |
|
| 2011-08 |
Identification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer |
Oncogene. 2011 Aug;30(33):3570-3584. |
|
| 2011-08 |
BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells |
PLoS ONE. 2011 Aug;6(8):Article number e23485. |
|
| 2011-07 |
MicroRNA signature and aberrant methylation in human oral squamous cell carcinomas |
Oral Oncology. 2011 Jul;47(Suppl. 1):S92. |
|
| 2011-06 |
Antimutagenic constituents of adlay ( Coix lachryma-jobi L. var. ma-yuen Stapf) with potential cancer chemopreventive activity |
Journal of Agricultural and Food Chemistry. 2011 Jun;59(12):6444-6452. |
|
| 2011-06 |
Aurora kinase inhibitor patents and agents in clinical testing: an update (2009-10) |
Expert Opinion on Therapeutic Patents. 2011 Jun;21(6):857-884. |
|
| 2011-05 |
Pharmacokinetic study with novel anticanacer agents, MPTOB124 and MPTOB214 |
Drug Metabolism Reviews. 2011 May;43(Suppl. 1):73. |
|
| 2011-04-28 |
Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents |
Journal of Medicinal Chemistry. 2011 Apr 28;54(8):3076-3080. |
|
| 2011-04-06 |
Indole compounds as inhibitors of tubulin polymerisation for the treatment of angiogenesis related disorders |
EP1506960/2011-04-06 |
|
| 2011-04 |
Concise syntheses of N-aryl-5,6,7-trimethoxyindoles as antimitotic and vascular disrupting agents: application of the copper-mediated Ullmann-type arylation |
Organic and Biomolecular Chemistry. 2011 Apr;9(9):3154-3157. |
|
| 2011-04 |
Activation of Akt/FoxO axis confers resistance to cisplatin in human nasopharyngeal carcinomas |
Cancer Research. 2011 Apr;71:Abstract number 1701. |
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