2014-08-15 |
Anticancer oral formulation |
特許第5596680號/2014-08-15 |
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2014-08-04 |
Effects of dipeptidyl peptidase-4 inhibition with MK-0431 on syngeneic mouse islet transplantation |
International Journal of Endocrinology. 2014 Aug 4;2014:Article ID 795283. |
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2014-08-01 |
Pyrrolidine derivatives |
特許第5,586,484號/2014-08-01 |
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2014-08 |
CDKN1A-mediated responsiveness of MLL-AF4-positive acute lymphoblastic leukemia to Aurora kinase-A inhibitors |
International Journal of Cancer. 2014 Aug;135(3):751-762. |
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2014-08 |
Cloning of a novel specific SCAR marker for species identification in Lactobacillus pentosus |
Molecular and Cellular Probes. 2014 Aug;28(4):192-194. |
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2014-08 |
Discovery and structure-activity relationships of phenyl benzenesulfonylhydrazides as novel indoleamine 2,3-dioxygenase inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2014 Aug;24(15):3403-3406. |
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2014-08 |
Ligand efficiency based approach for efficient virtual screening of compound libraries |
European Journal of Medicinal Chemistry. 2014 Aug;83:226-235. |
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2014-08 |
Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells |
Oncotarget. 2014 Aug;5(15):6087-6101. |
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2014-08 |
A novel mechanism for acupuncture-induced analgesia: involvement of orexins and endocannabinoids |
Journal of Neurochemistry. 2014 Aug;130(Suppl. s1):38. |
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2014-07-30 |
Pyrazole compounds |
ZA201303800B/2014-07-30 |
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2014-07 |
A novel approach to propagate flavivirus infectious cDNA clones in bacteria by introducing tandem repeat sequences upstream of virus genome |
Journal of General Virology. 2014 Jul;95(Pt 7):1493-1503. |
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2014-07 |
Anaplastic lymphoma kinase (ALK) inhibitors: A review of design and discovery |
MedChemComm. 2014 Jul;5(9):1266-1279. |
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2014-06-26 |
Baicalin, a metabolite of baicalein with antiviral activity against dengue virus |
Scientific Reports. 2014 Jun 26;4:Article number 5452. |
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2014-06-09 |
EDEM2 and OS-9 are required for ER-associated degradation of non-glycosylated sonic hedgehog |
PLoS ONE. 2014 Jun 9;9(6):Article number e92164. |
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2014-06-04 |
抗癌口服制剂 |
ZL200980126979.4/2014-06-04 |
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2014-05-12 |
Pyrrolidine derivatives |
J001349/2014-05-12 |
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2014-05-11 |
二苯並〔f,h〕異喹啉衍生物及其醫藥組成物 |
I436983/2014-05-11 |
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2014-05-08 |
Pyrrolidine derivatives |
AU2009222198/2014-05-08 |
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2014-05 |
Facile identification of dual FLT3-Aurora A inhibitors: A computer-guided drug design approach |
ChemMedChem. 2014 May;9(5):953-961. |
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2014-05 |
Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells |
Journal of Medicinal Chemistry. 2014 May;57(10):4009-4022. |
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2014-05 |
Cover Picture: Facile identification of dual FLT3–aurora a inhibitors: A computer-guided drug design approach (ChemMedChem 5/2014) |
ChemMedChem. 2014 May;9(5):861. |
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2014-05 |
High expression of Hsp90-beta and GRP 94 association with poor survival in resected non-small cell lung cancer patients |
Journal of Clinical Oncology. 2014 May;32(15, Suppl.):e13522. |
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2014-04-29 |
Quinoline compounds and their use for treating viral infection |
US8710079B2/2014-04-29 |
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2014-04-25 |
Pyrrolidine derivatives |
HK1149261/2014-04-25 |
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2014-04-21 |
咪唑-4-酮及咪唑-4-硫酮化合物 |
I434686/2014-04-21 |
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2014-04-21 |
作為蛋白質激酶抑制劑之吡唑化合物及噻唑化合物、其醫藥組成物及用途 |
I434834/2014-04-21 |
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2014-04-15 |
Glycoside compounds |
US8697658B2/2014-04-15 |
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2014-04 |
Treatment of chemotherapy-induced neutropenia in a rat model by using multiple daily doses of oral administration of G-CSF-containing nanoparticles |
Biomaterials. 2014 Apr;35(11):3641-3649. |
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2014-04 |
Antimitotic and vascular disrupting agents: 2-hydroxy-3,4,5-trimethoxybenzophenones |
European Journal of Medicinal Chemistry. 2014 Apr 22;77(2):306-314. |
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2014-04 |
Dysregulated affinity of lamin A to SUN1 induces nuclear and endoplasmic reticulum aberrancies in progeric laminopathies |
FASEB Journal. 2014 Apr;28(1 Suppl.):Article number 1009.1. |
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2014-03-21 |
菲并吲哚啶類似物 |
I430794/2014-03-21 |
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2014-03-20 |
Fused bicyclic pyrimidine compounds as aurora kinase inhibitors |
JP5502072/2014-03-20 |
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2014-03-11 |
脯胺酸衍生物 |
I429645/2014-03-11 |
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2014-03 |
Double michael addition reactions of the nazarov reagent with 2-cyano-2-cycloalkenones: An alternative approach to cis-fused bicyclic systems |
Synlett. 2014 Mar;25(4):543-546. |
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2014-03 |
DBPR112, a potent and selective EGFR kinase inhibitor in preclinical study |
Abstracts of Papers - American Chemical Society. 2014 Mar;247:Article number 315-MEDI. |
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2014-03 |
Efficient virtual screening using ligand efficiency based approach |
Abstracts of Papers - American Chemical Society. 2014 Mar;247:Article number 55-MEDI. |
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2014-02-19 |
Pyrrolidine derivatives |
EP2252582/2014-02-19 |
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2014-02 |
Utilization of elongation factor Tu gene (tuf) sequencing and species-specific PCR (SS-PCR) for the molecular identification of Acetobacter species complex |
Molecular and Cellular Probes. 2014 Feb;28(1):31-33. |
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2014-02 |
Role of HERP and a HERP-related protein in HRD1-dependent protein degradation at the endoplasmic reticulum |
Journal of Biological Chemistry. 2014 Feb 14;289 (7):4444-4454. |
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2014-02 |
Fibroblast activation protein (FAP) is essential for the migration of bone marrow mesenchymal stem cells through RhoA activation |
PLoS ONE. 2014 Feb 13;9(2):Article number e88772. |
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2014-02 |
Epstein-Barr virus BALF3 has nuclease activity and mediates mature virion production during the lytic cycle |
Journal of Virology. 2014 Feb;88(9):4962-4975. |
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2014-01-08 |
Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer |
PLoS ONE. 2014 Jan 8;9(1):Article number e83160. |
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2014-01-07 |
JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1alpha-mediated glucose metabolism |
Proceedings of the National Academy of Sciences of the United States of America. 2014 Jan 7;111(1):279-284. |
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2014-01 |
Molecular discrimination and identification of Acetobacter genus based on the partial heat shock protein 60 gene (hsp60) sequences |
Journal of the Science of Food and Agriculture. 2014 Jan;94(2):213-218. |
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2014-01 |
The gyrase B gene as a molecular marker to resolve interspecific relationships within the Acetobacter pasteurianus group and a novel target for species-specific PCR |
European Food Research and Technology. 2014 Jan;238(1):27-33. |
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2014-01 |
A novel dengue virus inhibitor, BP13944, discovered by high-throughput screening with dengue virus replicon cells selects for resistance in the viral NS2B/NS3 protease |
Antimicrobial Agents and Chemotherapy. 2014 Jan;58(1):110-119. |
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2014-01 |
Urinary metabolites of DEET after dermal application on child and adult subjects |
Journal of Environmental Health. 2014 Jan-Feb;76(6):162-169. |
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2013-12-18 |
吡咯烷化合物 |
ZL200980107941.2/2013-12-18 |
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2013-12 |
Evolutionarily conserved residues at an oligomerization interface of the influenza A virus neuraminidase are essential for viral survival |
Virology. 2013 Dec;447(1-3):32-44. |
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2013-12 |
Diterpenoids from the wood of Cunninghamia konishii |
Helvetica Chimica Acta. 2013 Dec;96(12):2282-2287. |
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