| 2024-10-29 |
DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration |
Journal of Medicinal Chemistry. 2024 Oct 29;Article in Press. |
 |
| 2024-09 |
Enhanced non-viral gene delivery via calcium phosphate/DNA co-precipitates with low-voltage pulse electroporation in NK-92 cells for immunocellular therapy |
APL Bioengineering. 2024 Sep;8:Article number 036107. |
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| 2024-08-14 |
Induction of thymus atrophy and disruption of thymocyte development by fipronil through dysregulation of IL-7-associated genes |
Chemical Research in Toxicology. 2024 Aug 14;Article in Press. |
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| 2024-08-02 |
A novel multitask learning algorithm for tasks with distinct chemical space: zebrafish toxicity prediction as an example |
Journal of Cheminformatics. 2024 Aug 02;16:Article number 91. |
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| 2024-07-31 |
Incorporating tissue-specific gene expression data to improve chemical-disease inference of in silico toxicogenomics methods |
Journal of Xenobiotics. 2024 Jul 31;14(3):1023-1035. |
|
| 2024-07-17 |
Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia |
Cell Chemical Biology. 2024 Jul 17;Article in Press. |
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| 2024-07-04 |
Development of a humanized antibody targeting extracellular HSP90alpha to suppress endothelial-mesenchymal transition-enhanced tumor growth of pancreatic adenocarcinoma cells |
Cells. 2024 Jul 04;13(13):Article number 1146. |
|
| 2024-06-24 |
Macrophage-mediated controlled release of cysteine protease inhibitor from PLGA-PEG/hydroxyapatite microspheres for targeting cathepsin S in Alzheimer's disease |
European Polymer Journal. 2024 Jun 24;214:Article number 113151. |
|
| 2024-06-24 |
Discovery of dual MER/AXL kinase inhibitors as bifunctional small molecules for inhibiting tumor growth and enhancing tumor immune microenvironment |
Journal of Medicinal Chemistry. 2024 Jun 24;Article in Press. |
|
| 2024-06-01 |
Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus |
Molecular Cancer Therapeutics. 2024 Jun 01;23(6):766-779. |
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| 2024-05-28 |
Chlorine-containing polyacetoxybriarane diterpenoids from the octocoral Junceella fragilis |
RSC Advances. 2024 May 28;14:17195-17201. |
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| 2024-05-09 |
Targeting cathepsin S promotes activation of OLF1-BDNF/TrkB axis to enhance cognitive function |
Journal of Biomedical Science. 2024 May 09;31:Article number 46. |
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| 2024-04 |
Design, synthesis, and anticancer evaluation of 1-benzo[1,3]dioxol-5-yl-3-N-fused heteroaryl indoles |
Molecular Diversity. 2024 Apr;28(2):595-608. |
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| 2024-04 |
BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase inhibitor, inhibits SARS-CoV-2 variants of concern and exerts synergistic antiviral activity in combination with remdesivir |
Antimicrobial Agents and Chemotherapy. 2024 Apr 3;68(4):Article number e0095623 |
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| 2024-04 |
Reducing brain Abeta burden ameliorates high-fat diet-induced fatty liver disease in APP/PS1 mice |
Biomedicine and Pharmacotherapy. 2024 Apr;173:Article number 116404. |
|
| 2024-03 |
Probing the hair detectability of prohibited substances in sports: An in vivo-in silico-clinical approach and analytical implications compared with plasma, urine, and faeces |
Archives of Toxicology. 2024 Mar;98(3):779-790. |
|
| 2024-03 |
Multitask learning for predicting pulmonary absorption of chemicals |
Food and Chemical Toxicology. 2024 Mar;185:Article number 114453. |
|
| 2024-03 |
Immunomodulatory and anti-angiogenesis effects of excavatolide B and its derivatives in alleviating atopic dermatitis |
Biomedicine and Pharmacotherapy. 2024 Mar;172:Article number 116279. |
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| 2024-02-16 |
Postfermented tea extract potently alleviates glucose metabolism disorders in vitro and in vivo |
ACS Food Science and Technology. 2024 Feb 16;4(2):479-490. |
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| 2024-02-15 |
Vitamin B12 inhibits peptidylarginine deiminases and ameliorates rheumatoid arthritis in CAIA mice |
Biochemical and Biophysical Research Communications. 2024 Feb 15;704:Article number 149668. |
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| 2024-01-23 |
Decrypting orphan GPCR drug discovery via multitask learning |
Journal of Cheminformatics. 2024 Jan 23;16:Article number 10. |
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| 2024-01-22 |
Fipronil disturbs the antigen-specific immune responses and GABAergic gene expression in the ovalbumin-immunized BALB/c mice |
BMC Veterinary Research. 2024 Jan 22;20:Article number 30. |
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| 2024-01-10 |
Exploring the relationship between gut microbiome composition and blood indole-3-acetic acid in hemodialysis patients |
Biomedicines. 2024 Jan 10;12(1):Article number 148. |
|
| 2023-12 |
Pulmonary delivery of remdesivir and dexamethasone encapsulated nanostructured lipid carriers for enhanced inflammatory suppression in lung |
Journal of Drug Delivery Science and Technology. 2023 Dec;90:Article number 105144. |
|
| 2023-11-15 |
Analysis of structure–activity relationship of indol-3-yl-N-phenylcarbamic amides as potent STING inhibitors |
Bioorganic and Medicinal Chemistry. 2023 Nov 15;95:Article number 117502. |
|
| 2023-11-03 |
Influence of ring strain on the formation of rearrangement vs cyclization isotwistane products in the acyl radical reaction of bicyclo[2.2.2]octanone |
Organic Letters. 2023 Nov 3;25(43):7757-7762. |
|
| 2023-11-01 |
MicroRNA regulators of vascular pathophysiology in chronic kidney disease |
Clinica Chimica Acta. 2023 Nov 1;551:Article number 117610. |
|
| 2023-11 |
Lysosomal-targeted doxorubicin delivery using RBC-derived vesicles to overcome drug-resistant cancer through mitochondrial-dependent cell death |
Pharmacological Research. 2023 Nov;197:Article number 106945. |
|
| 2023-10-26 |
Canine diffuse large b-cell lymphoma downregulates the activity of CD8 + T-cells through tumor-derived extracellular vesicles |
Cancer Cell International. 2023 Oct 26;23:Article number 252. |
|
| 2023-10-05 |
Discovery of tetrasubstituted thiophenes as Cisd2 activators: A potential novel therapeutic option in nonalcoholic fatty liver disease |
European Journal of Medicinal Chemistry. 2023 Oct 05;258:Article number 115583. |
|
| 2023-10-05 |
A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects |
European Journal of Medicinal Chemistry. 2023 Oct 05;258:Article number 115608. |
|
| 2023-10 |
16-Hydroxybriaranes from the octocoral Briareum stechei |
Phytochemistry Letters. 2023 Oct;57:92-95. |
|
| 2023-10 |
Discovery of novel AXL and MER inhibitors as potential anticancer and immune modulator drugs |
Annals of Oncology. 2023 Oct;34(Suppl. 2):S214. |
|
| 2023-08 |
Machine learning for predicting chemical migration from food packaging materials to foods |
Food and Chemical Toxicology. 2023 Aug;178:Article number 113942. |
|
| 2023-08 |
Mechanical transmission of dengue virus by Aedes aegypti may influence disease transmission dynamics during outbreaks |
eBioMedicine. 2023 Aug;Article number 104723. |
|
| 2023-07-20 |
Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin |
Biochemical Pharmacology. 2023 Jul 20;215:Article number 115688. |
|
| 2023-07-18 |
Marine diterpenoid targets STING palmitoylation in mammalian cells |
Communications Chemistry. 2023 Jul 18;6:Article number 153. |
|
| 2023-05-11 |
Induction of immune responses and phosphatidylserine exposure by TLR9 activation results in a cooperative antitumor effect with a phosphatidylserine-targeting prodrug |
International Journal of Biological Sciences. 2023 May 11;19(9):2648-2662. |
|
| 2023-03-28 |
Synthesis and structure–activity relationship of salvinal derivatives as potent microtubule inhibitors |
International Journal of Molecular Sciences. 2023 Mar 28;24(7):Article number 6386. |
|
| 2023-03-17 |
A convenient diels-alder approach toward potential polyketide-like antibiotics using alpha-activated alpha,Beta-unsaturated 4,4-dimethyl-1-tetralones as dienophiles |
Molecules. 2023 Mar 17;28(6):Article number 2739. |
|
| 2023-02-28 |
How to deal with frenemy NRF2: Targeting NRF2 for chemoprevention and cancer therapy |
Journal of Food and Drug Analysis. 2023 Feb 28;31(3):387-407. |
|
| 2023-02-13 |
Briavioid D, a rare 7Beta,8Beta-epoxybriarane from Briareum violaceum |
Tetrahedron Letters. 2023 Feb 13:Article number 154407. |
|
| 2023-02-07 |
Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer |
Journal of Medicinal Chemistry. 2023 Feb 7;66(4):2566-2588. |
|
| 2023-02-06 |
Using random forest to predict antimicrobial minimum inhibitory concentrations of nontyphoidal Salmonella in Taiwan |
Veterinary Research. 2023 Feb 06;54(1):Article number 11. |
|
| 2023-02-03 |
MiR-455-5p suppresses PDZK1IP1 to promote the motility of oral squamous cell carcinoma and accelerate clinical cancer invasion by regulating partial epithelial-to-mesenchymal transition |
Journal of Experimental and Clinical Cancer Research. 2023 Feb 3;42:Article number 40. |
|
| 2023-01-19 |
The synergistic inhibition of coronavirus replication and induced cytokine production by ciclesonide and the tylophorine-based compound dbq33b [Erratum:Pharmaceutics. 2022 Jul 21;14(7):Article number 1511.] |
Pharmaceutics. 2023 Jan 19;15(2):Article number 342. |
|
| 2023-01 |
Two new chromones and a new coumarin from the fruit of Cnidium monnieri (L.) Cusson |
Natural Product Research. 2023 Jan;37(1):47-55. |
|
| 2023-01 |
Modulating the affinity and signaling bias of cannabinoid receptor 1 antagonists |
Bioorganic Chemistry. 2023 Jan;130:Article number 106236. |
|
| 2022-12-05 |
Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation |
European Journal of Medicinal Chemistry. 2022 Dec 5;243:Article number 114728. |
|
| 2022-12-05 |
2,6-Difluorobenzamide derivatives as store-operated calcium channel (SOC) inhibitors |
European Journal of Medicinal Chemistry. 2022 Dec 5;243:Article number 114773. |
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