國家衛生研究院 NHRI:
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    最後更新時間: 2024-11-28 11:33

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    日期題名關聯
    2024-04 Design, synthesis, and anticancer evaluation of 1-benzo[1,3]dioxol-5-yl-3-N-fused heteroaryl indoles Molecular Diversity. 2024 Apr;28(2):595-608.
    2024-01-23 Decrypting orphan GPCR drug discovery via multitask learning Journal of Cheminformatics. 2024 Jan 23;16:Article number 10.
    2023-10-05 Discovery of tetrasubstituted thiophenes as Cisd2 activators: A potential novel therapeutic option in nonalcoholic fatty liver disease European Journal of Medicinal Chemistry. 2023 Oct 05;258:Article number 115583.
    2023-03-17 A convenient diels-alder approach toward potential polyketide-like antibiotics using alpha-activated alpha,Beta-unsaturated 4,4-dimethyl-1-tetralones as dienophiles Molecules. 2023 Mar 17;28(6):Article number 2739.
    2022-03-02 Discovery of potential neuroprotective agents against paclitaxel-induced peripheral neuropathy Journal of Medicinal Chemistry. 2022 Mar 2;65(6):4767-4782.
    2020-02 Design, synthesis and anticancer evaluation of beta-carboline-1-one hydantoins Future Medicinal Chemistry. 2020 Feb;12(3):183-192.
    2020-01-01 Delayed intervention with a novel SGLT2 inhibitor NGI001 suppresses diet-induced metabolic dysfunction and nonalcoholic fatty liver disease in mice British Journal of Pharmacology. 2020 Jan 1;177(2):239-253.
    2019-03 Synthesis and biological evaluation of N-glucosyl indole derivatives as sodium-dependent glucose co-transporter 2 inhibitors Bioorganic Chemistry. 2019 Mar;83:520-525.
    2018-01-01 Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2 European Journal of Medicinal Chemistry. 2018 Jan 1;143:611-620.
    2016-12-08 Bromomethylthioindole inspired carbazole hybrids as promising class of anti-MRSA agents ACS Medicinal Chemistry Letters. 2016 Dec 8;7(12):1191-1196.
    2016-09 Mycotoxin patulin suppresses innate immune responses by mitochondrial dysfunction and p62/sequestosome-1-dependent mitophagy Journal of Biological Chemistry. 2016 Sep;291(37):19299-19311.
    2016-07 Total synthesis of the naturally occurring glycosylflavone aciculatin Journal of Natural Products. 2016 Jul;79(7):1719-1723.
    2016-05 N-Indolylglycosides bearing modifications at the glucose C6-Position as Sodium-Dependent Glucose Co-transporter 2 inhibitors Bioorganic and Medicinal Chemistry. 2016 May;24(10):2242-2250.
    2015-08 Optimization of furanopyrimidine-based kinase inhibitors: Identification of a BTK kinase inhibitor for the treatment of B cell lymphoma Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 180.
    2015-07 Development and application of a fluorescent glucose uptake assay for the high-throughput screening of non-glycoside SGLT2 inhibitors European Journal of Pharmaceutical Sciences. 2015 Jul;74:40-44.
    2014-09 N-Iodosuccinimide and acid-washed molecular sieves (NIS/AW-300 MS) as promoters in thioglycoside activation Tetrahedron. 2014 Sep;70(38):6757-6762.
    2014-08 Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells Oncotarget. 2014 Aug;5(15):6087-6101.
    2014-04-15 Glycoside compounds US8697658B2/2014-04-15
    2012-09 Synthesis and biological evaluation of novel C-indolylxylosides as sodium-dependent glucose co-transporter 2 inhibitors European Journal of Medicinal Chemistry. 2012 Sep;55:32-38.
    2011-08 Colloid-based multiplexed screening for plant biomass-degrading glycoside hydrolase activities in microbial communities Energy and Environmental Science. 2011 Aug;4(8):2884-2893.
    2011-07-25 The first total synthesis of cytopiloyne, an anti-diabetic, polyacetylenic glucoside Chemistry-A European Journal. 2011 Jul 25;17(31):8696-8703.
    2011-06 Development of sodium-dependent glucose co-transporter 2 inhibitors as potential anti-diabetic therapeutics Current Topics In Medicinal Chemistry. 2011 Jun;11(12):1476-1512.
    2011-01-13 Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes Journal of Medicinal Chemistry. 2011 Jan 13;54(1):166-178.
    2010-12 Discovery of non-glycoside sodium-dependent glucose Co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening Journal of Medicinal Chemistry. 2010 Dec;53(24):8770-8774.

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