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http://ir.nhri.org.tw/handle/3990099045/1964
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| Title: | Variety of TEM-, SHV-, and CTX-M-type beta-lactamases present in recent clinical isolates of Escherichia coli, Klebsiella pneumoniae, and Enterobacter cloacae from Taiwan |
| Authors: | Ma, L;Chang, FY;Fung, CP;Chen, TL;Lin, JC;Lu, PL;Huang, LY;Chang, JC;Siu, LK |
| Contributors: | Division of Clinical Research |
| Abstract: | A total of 171 hospitals' isolates of E. coli, K. pneumoniae, and E. cloacae with a minimum inhibitory concentration (MIC) of >= 2 mu g/ml for ceftazidime or cefotaxime were evaluated for the production of beta-lactamases. PCR amplification with specific primers for the bla(SHV), bla(TEM), and bla(CTX) genes revealed that a total of 53, 81, and 43 of these genes were amplified, respectively. Sequencing results confirmed that TEM-1, CTX-M-3 and -14, SHV-1, -5, -11, -12, and -33, OXY-1a, and LEN-1 were presented among these isolates. No specific large cluster of isolates carried the same beta-lactamases, indicating the wide diversity of the collected strains. Plasmid spread between E. coli and K. neumoniae was identified in few isolates. Combinations of TEM, SHV, and CTX beta-lactamase genes, including extended-spectrum beta-lactamase genes, were observed in all three species. |
| Keywords: | Infectious Diseases;Microbiology;Pharmacology & Pharmacy |
| Date: | 2005-SPR |
| Relation: | Microbial Drug Resistance. 2005 Spr;11(1):31-39. |
| Link to: | http://dx.doi.org/10.1089/mdr.2005.11.31 |
| JIF/Ranking 2023: | http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1076-6294&DestApp=IC2JCR |
| Cited Times(WOS): | https://www.webofscience.com/wos/woscc/full-record/WOS:000227602500006 |
| Cited Times(Scopus): | http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=14944370004 |
| Appears in Collections: | [蕭樑基] 期刊論文
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| 000227602500006.pdf | | 192Kb | Adobe PDF | 337 | View/Open |
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