| 2009-04-01 |
Design, synthesis, and anti-HCV activity of thiourea compounds |
Bioorganic and Medicinal Chemistry Letters. 2009 Apr 1;19(7):1950-1955. |
 |
| 2009-03 |
Discovery and development of novel furano-pyrimidine analogs as Aurora kinase inhibitors |
Abstracts of Papers - American Chemical Society. 2009 Mar;237:MEDI 221. |
|
| 2009-02-26 |
Structure-based drug design of novel aurora kinase a inhibitors: Structural basis for potency and specificity |
Journal of Medicinal Chemistry. 2009 Feb 26;52(4):1050-1062. |
|
| 2009-02 |
Aurintricarboxylic acid inhibits influenza virus neuraminidase |
Antiviral Research. 2009 Feb;81(2):123-131. |
|
| 2008-12-11 |
吲哚化合物 |
I304066/2008-12-11 |
|
| 2008-12 |
Mana-Hox displays anticancer activity against prostate cancer cells through tubulin depolymerization and DNA damage stress |
Naunyn-Schmiedeberg's Archives of Pharmacology. 2008 Dec;378(6):599-608. |
|
| 2008-11-11 |
Indole compounds |
US7449478B2/2008-11-11 |
|
| 2008-11 |
Amantadine as a regulator of internal ribosome entry site |
Acta Pharmacologica Sinica. 2008 Nov;29(11):1327-1333. |
|
| 2008-08-01 |
Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents |
Bioorganic and Medicinal Chemistry. 2008 Aug 1;16(15):7388-7398. |
|
| 2008-07 |
Anti-HSV activity of digitoxin and its possible mechanisms |
Antiviral Research. 2008 Jul;79(1):62-70. |
|
| 2008-06-01 |
A cell-based high-throughput screen for epidermal growth factor receptor pathway inhibitors |
Analytical Biochemistry. 2008 Jun;377(1):89-94. |
|
| 2008-05 |
Bioassay-guided purification and identification of PPARa/gamma agonists from Chlorella sorokiniana |
Phytotherapy Research. 2008 May;22(5):605-613. |
|
| 2008-04-01 |
A mammalian cell-based reverse two-hybrid system for functional analysis of 3C viral protease of human enterovirus 71 |
Analytical Biochemistry. 2008 Apr;375(1):115-123. |
|
| 2008-03-01 |
Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold |
Bioorganic and Medicinal Chemistry Letters. 2008 Mar;18(5):1623-1627. |
|
| 2008-02-11 |
一種抗病毒之醫藥組合物 |
I293248/2008-02-11 |
|
| 2007-12 |
Strategies of development of antiviral agents directed against influenza virus replication |
Current Pharmaceutical Design. 2007 Dec;13(34):3531-3542. |
|
| 2007-09 |
Sf-Caspase-I-repressed stable cells: resistance to apoptosis and augmentation of recombinant protein production |
Biotechnology and Applied Biochemistry. 2007 Sep;48(Pt. 1):11-19. |
|
| 2007-07 |
Anti-influenza drug discovery |
Drugs of the Future. 2007 Jul;32(Suppl. A):97. |
|
| 2007-03-01 |
用於治療黃病毒科病毒感染之醫藥組合物、套組、及包裝產品 |
I274585/2007-03-01 |
|
| 2007-02-08 |
Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells |
Cancer Letters. 2007 Feb;246(1-2):237-252. |
|
| 2006-11-25 |
The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes |
Life Sciences. 2006 Nov;79(26):2432-2440. |
|
| 2006-10-19 |
Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists |
Journal of Medicinal Chemistry. 2006 Oct;49(21):6421-6424. |
|
| 2006-08-01 |
抗腸病毒化合物 |
I259083/2006-08-01 |
|
| 2006-07 |
Antiviral drug discovery against SARS-CoV |
Current Medicinal Chemistry. 2006 Jul;13(17):2003-2020. |
|
| 2006-05-04 |
Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities |
Journal of Medicinal Chemistry. 2006 May;49(9):2703-2712. |
|
| 2006-04-19 |
用於治療黃病毒科病毒感染之醫藥組合物、套組、及包裝產品 |
ZL03138694.6/2006-04-19 |
|
| 2006-02-09 |
Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies |
Journal of Medicinal Chemistry. 2006 Feb;49(3):1212-1216. |
|
| 2006-02 |
Stable RNA interference in Spodoptera frugiperda cells by a DNA vector-based method |
Biotechnology Letters. 2006 Feb;28(4):271-277. |
|
| 2006-01-01 |
Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system |
Bioorganic and Medicinal Chemistry. 2006 Jan 1;14(1):83-91. |
|
| 2006 |
Antiviral drug discovery targeting to viral proteases |
Current Pharmaceutical Design. 2006;12(11):1301-1314. |
|
| 2005-12-29 |
Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities |
Journal of Medicinal Chemistry. 2005 Dec;48(26):8194-8208. |
|
| 2005-11 |
Emergence of mutation clusters in the HCV genome during sequential viral passages in Sip-L expressing cells |
Journal of Virological Methods. 2005 Nov;129(2):170-177. |
|
| 2005-10 |
Inhibition of hepatitis C virus replication by antimonial compounds |
Antimicrobial Agents and Chemotherapy. 2005 Oct;49(10):4197-4202. |
|
| 2005-08-02 |
Papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV): Expression, purification, characterization, and inhibition |
Biochemistry. 2005 Aug;44(30):10349-10359. |
|
| 2005-08 |
High-throughput cell-based screening for hepatitis C virus NS3/4A protease inhibitors |
ASSAY and Drug Development Technologies. 2005 Aug;3(4):385-392. |
|
| 2005-06-05 |
High-efficiency protein expression mediated by enterovirus 71 internal ribosome entry |
Biotechnology and Bioengineering. 2005 Jun;90(5):656-662. |
|
| 2005-04-22 |
Anti-HCV activities of selective polyunsaturated fatty acids [Erratum: Biochemical and Biophysical Research Communications. 2004 May;318(1):275-280.] |
Biochemical and Biophysical Research Communications. 2005 Apr;329(4):1360. |
|
| 2005-03 |
Promazine analogues as potential anti SARS-CoV drugs |
Abstracts of Papers of the American Chemical Society. 2005 Mar;229(Part 2):U168. |
|
| 2005-03 |
Design, synthesis and sar of indole-based PPAR agonists |
Abstracts of Papers of the American Chemical Society. 2005 Mar;229(Part 2):U141. |
|
| 2005-03 |
Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents |
Abstracts of Papers of the American Chemical Society. 2005 Mar;229(Part 2):U141. |
|
| 2005 |
Inhibition of SARS-CoV 3C-like protease activity by theaflavin-3,3 '- digallate (TF3) |
Evidence-based Complementary and Alternative Medicine. 2005;2:209-215. |
|
| 2004-11-09 |
Anti-enterovirus compounds |
US6815444B2/2004-11-09 |
|
| 2004-10 |
Biosynthesis of human-type N-glycans in heterollogous systems |
Current Opinion in Structural Biology. 2004 Oct;14(5):601-606. |
|
| 2004-10 |
Emergence of mutation clusters in HCV genome during continuous passage of the virus in Sip-L expressing cells |
Hepatology. 2004 Oct;40(4):255A. |
|
| 2004-09-10 |
Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV |
FEBS Letters. 2004 Sep;574(1-3):116-120. |
|
| 2004-08 |
Inhibition of hepatitis C virus replication by arsenic trioxide |
Antimicrobial Agents and Chemotherapy. 2004 Aug;48(8):2876-2882. |
|
| 2004-07-23 |
Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate [Erratum: Biochemical and Biophysical Research Communications. 2004 Jun;318(4):862-867.] |
Biochemical and Biophysical Research Communications. 2004 Jul;320(2):623-623. |
|
| 2004-07 |
Inhibition of severe acute respiratory syndrome coronavirus replication by niclosamide |
Antimicrobial Agents and Chemotherapy. 2004 Jul;48(7):2693-2696. |
|
| 2004-06-11 |
Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate |
Biochemical and Biophysical Research Communications. 2004 Jun;318(4):862-867. |
|
| 2004-05-21 |
Anti-HCV activities of selective polyunsaturated fatty acids |
Biochemical and Biophysical Research Communications. 2004 May;318(1):275-280. |
|
