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生技與藥物研究所
陳新(2002-2015)
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徐祖安
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李靜琪
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林書玉
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洪明秀
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潘秀玲(2009-2013)
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王文傑
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王鴻俊
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石全(2014-2017)
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童俊維
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郭靜娟
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陳志豪
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顏婉菁
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許明珠(1997-2001)
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陳淑貞(1998-2001)
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陳華鍵(1997-2001)
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最後更新時間: 2024-12-01 03:12
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Probing for improved selectivity wi...
吡咯啶化合物
Pyrrolidine compounds
Pyrrolidine compounds
吡咯烷化合物
Pyrrolidine compounds
Pyrrolidine compounds
吲哚化合物
吡咯啉啶化合物
吲哚化合物
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Showing items 26-50 of 67. (3 Page(s) Totally)
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Date
Title
Relation
2009-06
A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitiors [Erratum: European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.]
European Journal of Medicinal Chemistry. 2009 Jun;44(6):2763-2763.
2009-05-15
Biochemical properties and expression profile of human prolyl dipeptidase DPP9
Archives of Biochemistry and Biophysics. 2009 May 15;485(2):120-127.
2009-04-23
Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists
Journal of Medicinal Chemistry. 2009 Apr 23;52(8):2618-2622.
2009-04-01
Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors
Bioorganic and Medicinal Chemistry Letters. 2009 Apr 1;19(7):1908-1912.
2009-03-15
Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors
Bioorganic and Medicinal Chemistry. 2009 Mar 15;17(6):2388-2399.
2009-01-22
Pyrrolidine compounds
AU2005221678/2009-01-22
2009
Thiopurine analogue inhibitors of severe acute respiratory syndrome-coronavirus papain-like protease, a deubiquitinating and deISGylating enzyme
Antiviral Chemistry and Chemotherapy. 2009;19(4):151-156.
2008-12-11
吲哚化合物
I304066/2008-12-11
2008-11-11
Indole compounds
US7449478B2/2008-11-11
2008-08
A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors
European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.
2008-07-21
吡咯啉啶化合物
I299039/2008-07-21
2008-07-15
Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 1: Identification of dipeptide derived leads
Bioorganic and Medicinal Chemistry Letters. 2008 Jul;18(14):4154-4158.
2008-07-15
Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: Isoindoline containing inhibitors
Bioorganic and Medicinal Chemistry Letters. 2008 Jul;18(14):4159-4162.
2008-07-01
Pyrrolidine compounds
KR10-0844593/2008-07-01
2008-05-01
Purification and characterization of a dipeptidyl peptidase 9-like enzyme from bovine testes
Frontiers in Bioscience. 2008 May 1;13(9):3558-3568.
2008-05
Bioassay-guided purification and identification of PPARa/gamma agonists from Chlorella sorokiniana
Phytotherapy Research. 2008 May;22(5):605-613.
2008-04-15
Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus
Biochemical Pharmacology. 2008 Apr;75(8):1601-1609.
2008-04-06
COMP 266-Structure, function and inhibitors of prolyl dipeptidase DPP8
Abstracts of Papers - American Chemical Society. 2008 Apr 6;235:266-COMP.
2007-11-15
Irreversible inhibition of dipeptidyl peptidase 8 by dipeptide-derived diaryl phosphonates
Journal of Medicinal Chemistry. 2007 Nov;50(23):5568-5570.
2007-05
Dipeptidyl peptidase 8/9-like activity in human leukocytes
Journal of Leukocyte Biology. 2007 May;81(5):1252-1257.
2007-03-01
3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes
Bioorganic and Medicinal Chemistry Letters. 2007 Mar;17(5):1274-1279.
2006-12-15
Investigation of the dimer interface and substrate specificity of prolyl dipeptidase DPP8
Journal of Biological Chemistry. 2006 Dec;281(50):38653-38662.
2006-12
Biochemical properties of recombinant prolyl dipeptidases DPP-IV and DPP8
Advances in Experimental Medicine and Biology. 2006 Dec;575:27-32.
2006-10-19
Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists
Journal of Medicinal Chemistry. 2006 Oct;49(21):6421-6424.
2006-09
MEDI 416-3- 2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino -3-methyl-butyr amide analogs as DPP-IV inhibitors for the treatment of type-II diabetes
Abstracts of Papers - American Chemical Society. 2006 Sep;232:MEDI 416.
Showing items 26-50 of 67. (3 Page(s) Totally)
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